Results 1 to 10 of about 2,719,319 (244)
Lipid and Lipoprotein Metabolism in Microglia [PDF]
Frontiers in Physiology, 2020 Microglia, once viewed as static bystanders with limited homeostatic functions, are now considered key players in the development of neuroinflammatory and neurodegenerative diseases.
Bailey A. Loving, Kimberley D. Bruce
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Lipoprotein metabolism in familial hypercholesterolemia [PDF]
Journal of Lipid Research, 2021 Familial hypercholesterolemia (FH) is one of the most common genetic disorders in humans. It is an extremely atherogenic metabolic disorder characterized by lifelong elevations of circulating LDL-C levels often leading to premature cardiovascular events.
Kévin Chemello +5 more
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A new phenotypic classification system for dyslipidemias based on the standard lipid panel
Lipids in Health and Disease, 2021 Highlights A new algorithm is described for categorizing dyslipidemic patients into Fredrickson-like lipoprotein phenotypes except for Type III. The new lipoprotein phenotypes were validated by NMR-lipoprotein analysis and by agarose gel electrophoresis ...
Maureen Sampson +15 more
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Influence of proteinuria on the lipoprotein (a) metabolism disorder [PDF]
Vojnosanitetski Pregled, 2005 Background/Aim. Proteinuria causes lipid metabolism abnormalities. The aim of the present study was to examine the influence of proteinuria on the lipoprotein (a) metabolism disorder. Methods.
Petrović Dejan +2 more
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Lipoprotein metabolism indicators improve cardiovascular risk prediction. [PDF]
PLoS ONE, 2014 BACKGROUND: Cardiovascular disease risk increases when lipoprotein metabolism is dysfunctional. We have developed a computational model able to derive indicators of lipoprotein production, lipolysis, and uptake processes from a single lipoprotein profile
Daniël B van Schalkwijk +7 more
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Causal associations between disorders of lipoprotein metabolism and ten cardiovascular diseases
Frontiers in Cell and Developmental Biology, 2022 Disorders of lipoprotein metabolism have been linked with an increased risk of cardiovascular diseases (CVDs) but the causal association is unclear. In this study, we investigated the causal association between disorders of lipoprotein metabolism and ...
Qiannan Gao +5 more
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Frontiers in Physiology, 2021 Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a convertase enzyme mostly produced by the liver. It is a key regulator of LDL metabolism because of its ability to enhance degradation of the LDL receptor.
Qidi Ying +3 more
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Universal scaling relation and criticality in metabolism and growth of Escherichia coli [PDF]
Phys. Rev. Research 6, 013035 (2024), 2023 The metabolic network plays a crucial role in regulating bacterial metabolism and growth, but it is subject to inherent molecular stochasticity. Previous studies have utilized flux balance analysis and the maximum entropy method to predict metabolic fluxes and growth rates, while the underlying principles governing bacterial metabolism and growth ...
arxiv +1 more source
Journal of Lipid Research, 2022 Lipoprotein(a) [Lp(a)] concentrations are regulated by the LPA gene mainly via the large kringle IV-type 2 (KIV-2) copy number variation and multiple causal variants.
Rebecca Grüneis +10 more
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Antioxidants and lipoprotein metabolism [PDF]
Proceedings of the Nutrition Society, 1999 Lipoprotein metabolism plays a significant role in the pathogenesis of atherosclerosis and risk of vascular disease. Elevated levels of LDL and low levels of HDL are linked to the risk of cardiovascular disease. It is now widely accepted that oxidative modification of LDL affects the metabolism of lipoproteins, leading to their increased accumulation ...
Mridula Chopra, David I. Thurnham
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