Results 1 to 10 of about 219,582 (315)

Influence of proteinuria on the lipoprotein (a) metabolism disorder [PDF]

Vojnosanitetski Pregled, 2005
Background/Aim. Proteinuria causes lipid metabolism abnormalities. The aim of the present study was to examine the influence of proteinuria on the lipoprotein (a) metabolism disorder. Methods.
Petrović Dejan, Obrenović Radmila, Stojimirović Biljana   +2 more
doaj   +3 more sources

The metabolism of lipoprotein (a): an ever-evolving story [PDF]

Journal of Lipid Research, 2017
Lipoprotein (a) [Lp(a)] is characterized by apolipoprotein (a) [apo(a)] covalently bound to apolipoprotein B 100. It was described in human plasma by Berg et al.
Gissette Reyes-Soffer, Henry N. Ginsberg, Rajasekhar Ramakrishnan   +2 more
doaj   +3 more sources

The kringle IV type 2 domain variant 4925G>A causes the elusive association signal of the LPA pentanucleotide repeat

Journal of Lipid Research, 2022
Lipoprotein(a) [Lp(a)] concentrations are regulated by the LPA gene mainly via the large kringle IV-type 2 (KIV-2) copy number variation and multiple causal variants.
Rebecca Grüneis, Hansi Weissensteiner, Claudia Lamina, Sebastian Schönherr, Lukas Forer, Silvia Di Maio, Gertraud Streiter, Annette Peters, Christian Gieger, Florian Kronenberg, Stefan Coassin   +10 more
doaj   +1 more source

Reducing saturated fat intake lowers LDL-C but increases Lp(a) levels in African Americans: the GET-READI feeding trial

Journal of Lipid Research, 2023
Reducing dietary saturated fatty acids (SFA) intake results in a clinically significant lowering of low-density lipoprotein cholesterol (LDL-C) across ethnicities.
Hayley G. Law, Muhammad A. Khan, Wei Zhang, Heejung Bang, Jennifer Rood, Marlene Most, Michael Lefevre, Lars Berglund, Byambaa Enkhmaa   +8 more
doaj   +1 more source

Dietary fish oil enriched in very-long-chain polyunsaturated fatty acid reduces cardiometabolic risk factors and improves retinal function

iScience, 2023
Summary: Very-long-chain polyunsaturated fatty acids (VLCPUFAs; C24-38) constitute a unique class of PUFA that have important biological roles, but the lack of a suitable dietary source has limited research in this field.
Zhi-Hong Yang, Aruna Gorusupudi, Todd A. Lydic, Anupam K. Mondal, Seizo Sato, Isao Yamazaki, Hideaki Yamaguchi, Jingrong Tang, Krishna Vamsi Rojulpote, Anna B. Lin, Hannah Decot, Hannah Koch, Daniel C. Brock, Ranganathan Arunkumar, Zhen-Dan Shi, Zu-Xi Yu, Milton Pryor, Julia F. Kun, Rolf E. Swenson, Anand Swaroop, Paul S. Bernstein, Alan T. Remaley   +21 more
doaj   +1 more source

A new phenotypic classification system for dyslipidemias based on the standard lipid panel

Lipids in Health and Disease, 2021
Highlights A new algorithm is described for categorizing dyslipidemic patients into Fredrickson-like lipoprotein phenotypes except for Type III. The new lipoprotein phenotypes were validated by NMR-lipoprotein analysis and by agarose gel electrophoresis ...
Maureen Sampson, Rami A. Ballout, Daniel Soffer, Anna Wolska, Sierra Wilson, Jeff Meeusen, Leslie J. Donato, Erica Fatica, James D. Otvos, Eliot A. Brinton, Robert S. Rosenson, Peter Wilson, Marcelo Amar, Robert Shamburek, Sotirios K. Karathanasis, Alan T. Remaley   +15 more
doaj   +1 more source

A Dynamical Model of Lipoprotein Metabolism [PDF]

Bulletin of Mathematical Biology, 2007
We present a dynamical model of lipoprotein metabolism derived by combining a cascading process in the blood stream and cellular level regulatory dynamics. We analyse the existence and stability of equilibria and show that this low-dimensional, nonlinear model exhibits bistability between a low and a high cholesterol state.
August, E, Parker, KH, Barahona, M
openaire   +6 more sources

Triglyceride Metabolism Modifies Lipoprotein(a) Plasma Concentration

The Journal of Clinical Endocrinology & Metabolism, 2022
AbstractBackgroundLipoprotein(a) (Lp(a)) is a significant cardiovascular risk factor. Knowing the mechanisms that regulate its concentration can facilitate the development of Lp(a)-lowering drugs. This study analyzes the relationship between triglycerides (TGs) and Lp(a) concentrations, cross-sectionally and longitudinally, and the influence of the ...
Maria Ramos-Cáceres, Itziar Lamiquiz-Moneo, Ana Cenarro, Pilar Calmarza, Victoria Marco-Benedí, Ana M Bea, Rocio Mateo-Gallego, Jose Puzo, Jose M Ordovas, Fernando Civeira, Martin Laclaustra   +10 more
openaire   +4 more sources

Lipoprotein metabolism indicators improve cardiovascular risk prediction. [PDF]

PLoS ONE, 2014
BACKGROUND: Cardiovascular disease risk increases when lipoprotein metabolism is dysfunctional. We have developed a computational model able to derive indicators of lipoprotein production, lipolysis, and uptake processes from a single lipoprotein profile
Daniël B van Schalkwijk, Albert A de Graaf, Evgeni Tsivtsivadze, Laurence D Parnell, Bianca J C van der Werff-van der Vat, Ben van Ommen, Jan van der Greef, José M Ordovás   +7 more
doaj   +1 more source

Causal associations between disorders of lipoprotein metabolism and ten cardiovascular diseases

Frontiers in Cell and Developmental Biology, 2022
Disorders of lipoprotein metabolism have been linked with an increased risk of cardiovascular diseases (CVDs) but the causal association is unclear. In this study, we investigated the causal association between disorders of lipoprotein metabolism and ...
Qiannan Gao, Jiang-Shan Tan, Luyun Fan, Xiaoqi Wang, Lu Hua, Jun Cai   +5 more
doaj   +1 more source