Results 11 to 20 of about 115,025,331 (252)

Peroxisome Proliferator Activated Receptors and Lipoprotein Metabolism [PDF]

PPAR Research, 2008
Plasma lipoproteins are responsible for carrying triglycerides and cholesterol in the blood and ensuring their delivery to target organs. Regulation of lipoprotein metabolism takes place at numerous levels including via changes in gene transcription.
Sander Kersten
doaj   +2 more sources

Impact of protein glycosylation on lipoprotein metabolism and atherosclerosis [PDF]

, 2021
Protein glycosylation is a post-translational modification consisting of the enzymatic attachment of carbohydrate chains to specific residues of the protein sequence.
Catapano, Alberico Luigi, Svecla, Monika, Catapano, Alberico L, Holleboom, Adriaan G, Holleboom, Adriaan G., Pirillo, Angela, Norata, Giuseppe D, Norata, Giuseppe Danilo   +7 more
core   +1 more source

Conjugated linoleic acid supplementation, insulin sensitivity, and lipoprotein metabolism in patients with type 2 diabetes mellitus. [PDF]

, 2004
BACKGROUND: Some animal studies have suggested that conjugated linoleic acid (CLA) supplementation may have therapeutic potential with respect to insulin sensitivity and lipid metabolism, which are important cardiovascular disease (CVD) risk factors ...
Mullen, Anne, Anne Mullen, John J Nolan, Moloney, F, Yeow, Toh-Peng, Toh-Peng Yeow, Helen M Roche, Yeow, TP, Roche, HM, Fiona Moloney, Mullen, A, Nolen, JJ, Moloney, Fiona, Nolan, John J, Roche, Helen M   +14 more
core   +1 more source

Genome-wide association study of genetic determinants of LDL-c response to atorvastatin therapy: importance of Lp(a)

Journal of Lipid Research, 2012
We carried out a genome-wide association study (GWAS) of LDL-c response to statin using data from participants in the Collaborative Atorvastatin Diabetes Study (CARDS; n = 1,156), the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT; n = 895), and the ...
Harshal A. Deshmukh, Helen M. Colhoun, Toby Johnson, Paul M. McKeigue, D. John Betteridge, Paul N. Durrington, John H. Fuller, Shona Livingstone, Valentine Charlton-Menys, Andrew Neil, Neil Poulter, Peter Sever, Denis C. Shields, Alice V. Stanton, Aurobindo Chatterjee, Craig Hyde, Roberto A. Calle, David A. DeMicco, Stella Trompet, Iris Postmus, Ian Ford, J. Wouter Jukema, Mark Caulfield, Graham A. Hitman   +23 more
doaj   +1 more source

Effect of a high intake of conjugated linoleic acid on lipoprotein levels in healthy human subjects [PDF]

, 2010
Background -Trans fatty acids are produced either by industrial hydrogenation or by biohydrogenation in the rumens of cows and sheep. Industrial trans fatty acids lower high-density lipoprotein (HDL) cholesterol, raise low-density lipoprotein (LDL ...
Wanders Anne J., Siebelink, E., Brouwer, I.A.; id_orcid, Martijn B. Katan, Katan Martijn B., Martijn B Katan, Ingeborg A Brouwer, Brouwer, I.A., Els Siebelink, Anne J. W, Katan, M.B.; id_orcid, Katan, M.B., Anne J Wanders, Siebelink Els, Wanders, A.J., Ingeborg A. Brouwer, Brouwer Ingeborg A.   +16 more
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Dydrogesterone and norethisterone regulate expression of lipoprotein lipase and hormones-sensitive lipase in human subcutaneous abdominal adipocytes [PDF]

, 2007
Aim: In premenopausal women, hyper-androgenicity is associated with central obesity and an increased cardiovascular risk. We investigated the effects of dydrogesterone (DYD)(a non-androgenic progestogen) and norethisterone (NET)(an androgenic progestogen)
Sturdee, D. W., D. W. Sturdee, Palin, SL, Barnett, Anthony, S. L. Palin, K. C. McGee, Kumar, Sudhesh, McTernan, PG, McTernan, P. G., Barnett, A. H., Sturdee, David, Kumar, S, A. H. Barnett, McGee, K. C., McGee, KC, P. G. McTernan, Palin, S. L., S. Kumar   +17 more
core   +1 more source

Mathematical model for low density lipoprotein (LDL) endocytosis by hepatocytes [PDF]

, 2008
Individuals with elevated levels of plasma low density lipoprotein (LDL) cholesterol (LDL-C) are considered to be at risk of developing coronary heart disease.
B. O’Malley, J. A. D. Wattis, H. Blackburn, Wattis, JA, H. M. Byrne, L. Pickersgill, O'Malley, B, Panovska, J, Pickersgill, L, Blackburn, H, Byrne, HM, Byrne, Helen, K. G. Jackson, Wattis, JAD, Jackson, KG, J. Panovska, Panovska, J., O'Malley, B., Pickersgill, L., Wattis, J.A.D., Jackson, K.G., Blackburn, H., Byrne, H.M.   +22 more
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A Role of the Bile Salt Receptor FXR in Atherosclerosis [PDF]

, 2010
This study reviews current insights into the role of bile salts and bile salt receptors on the progression and regression of atherosclerosis. Bile salts have emerged as important modifiers of lipid and energy metabolism.
Albert K. Groen, Hageman, Jurre, Herrema, H.J., Folkert Kuipers, Hageman, J., Kuipers, Folkert, Herrema, Hilde, Hilde Herrema, Kuipers, Folkert; id_orcid, Groen, A.K., Kuipers, F., Groen, Albert K., Jurre Hageman   +12 more
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Plasma lipoproteins: apolipoprotein structure and function.

Journal of Lipid Research, 1984
Plasma lipoprotein metabolism is regulated and controlled by the specific apolipoprotein (apo-) constituents of the various lipoprotein classes. The major apolipoproteins include apoE, apoB, apoA-I, apoA-II, apoA-IV, apoC-I, apoC-II, and apoC-III ...
R W Mahley, T L Innerarity, S C Rall, Jr, K H Weisgraber   +3 more
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Dietary medium chain fatty acid supplementation leads to reduced VLDL lipolysis and uptake rates in comparison to linoleic acid supplementation. [PDF]

PLoS ONE, 2014
Dietary medium chain fatty acids (MCFA) and linoleic acid follow different metabolic routes, and linoleic acid activates PPAR receptors. Both these mechanisms may modify lipoprotein and fatty acid metabolism after dietary intervention.
Daniël B van Schalkwijk, Wilrike J Pasman, Henk F J Hendriks, Elwin R Verheij, Carina M Rubingh, Kees van Bochove, Wouter H J Vaes, Martin Adiels, Andreas P Freidig, Albert A de Graaf   +9 more
doaj   +1 more source