Results 1 to 10 of about 95,116 (303)
Lipoprotein lipase (LPL) regulates the plasma levels of triglyceride and HDL. Three aspects are reviewed. 1) Clinical implications of human LPL gene variations: common mutations and their effects on plasma lipids and coronary heart disease are discussed.
Martin Merkel +2 more
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The rate at which lipoprotein lipase hydrolyzes triglycerides in lipQproteins and in synthetic emulsions decreases sharply with the amount of products formed unless albumin is present. Three factors which contribute to this inhibition as follows. (a) The fatty acids and the monoglycerides formed on hydrolysis locate at the lipidâwater interface of the ...
G, Bengtsson, T, Olivecrona
openaire +4 more sources
Lipoprotein lipase and hepatic lipase [PDF]
HDL subspecies Lp(A-I) and Lp(A-I,A-II) have different anti-atherogenic potentials. To determine the role of lipoprotein lipase (LPL) and hepatic lipase (HL) in regulating these particles, we measured these enzyme activities in 28 healthy subjects with ...
Marian C. Cheung +4 more
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The lipoprotein lipase of mammary gland and the correlation of its activity to lactation
The concentration of lipoprotein lipase of guinea pig mammary gland increases markedly just prior to parturition, reaching a maximal level within 2 hr post-partum.
O.W. McBride, Edward D. Korn
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Striated muscle gene therapy for the treatment of lipoprotein lipase deficiency. [PDF]
Excessive circulating triglycerides due to reduction or loss of lipoprotein lipase activity contribute to hypertriglyceridemia and increased risk for pancreatitis.
Katherine E Gadek +7 more
doaj +1 more source
Stabilizing lipoprotein lipase [PDF]
Evidence from several prospective observational studies points toward the independent predictive value of plasma triglycerides in assessing cardiovascular risk (1). Hence, plasma triglycerides are increasingly targeted as a specific cardiovascular treatment outcome.
Kersten, A.H., Bensadoun, A.
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Over-expression of human lipoprotein lipase in mouse mammary glands leads to reduction of milk triglyceride and delayed growth of suckling pups. [PDF]
BACKGROUND: The mammary gland is a conserved site of lipoprotein lipase expression across species and lipoprotein lipase attachment to the luminal surface of mammary gland vascular endothelial cells has been implicated in the direction of circulating ...
Yuanyuan Wang +11 more
doaj +1 more source
3T3-L1 adipocytes were used to test the hypothesis that hormone-sensitive lipolysis and lipoprotein lipase activity might be regulated in a reciprocal manner.
S S Chernick +3 more
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The mechanism of heparin stimulation of rat adipocyte lipoprotein lipase
Free fat cells and stromal-vascular cells were prepared from rat adipose tissue by incubation with collagenase. NH4OH-NH4Cl extracts of acetone-ether powders prepared from fat cells contained lipoprotein lipase activity but extracts of stromal-vascular ...
R.L. Patten, C.H. Hollenberg
doaj +1 more source
To test whether lipoprotein lipase or hepatic lipase activities are associated with lipoprotein subclasses, and to assess the effects of dietary manipulations on these associations, enzyme activities were measured in postheparin plasma (75 U heparin/kg ...
H Campos, D M Dreon, R M Krauss
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