Cryogenic electron tomography reveals helical organization of lipoprotein lipase in storage vesicles. [PDF]
Sci AdvGunn KH +7 more
europepmc +2 more sources
Striated muscle gene therapy for the treatment of lipoprotein lipase deficiency. [PDF]
PLoS ONE, 2018 Excessive circulating triglycerides due to reduction or loss of lipoprotein lipase activity contribute to hypertriglyceridemia and increased risk for pancreatitis.
Katherine E Gadek +7 more
doaj +1 more source
Over-expression of human lipoprotein lipase in mouse mammary glands leads to reduction of milk triglyceride and delayed growth of suckling pups. [PDF]
PLoS ONE, 2011 BACKGROUND: The mammary gland is a conserved site of lipoprotein lipase expression across species and lipoprotein lipase attachment to the luminal surface of mammary gland vascular endothelial cells has been implicated in the direction of circulating ...
Yuanyuan Wang +11 more
doaj +1 more source
Journal of Lipid Research, 2002 Lipoprotein lipase (LPL) regulates the plasma levels of triglyceride and HDL. Three aspects are reviewed. 1) Clinical implications of human LPL gene variations: common mutations and their effects on plasma lipids and coronary heart disease are discussed.
Martin Merkel +2 more
doaj +1 more source
Rat liver contains a limited number of binding sites for hepatic lipase [PDF]
, 1994 The binding of hepatic lipase to rat liver was studied in an ex vivo perfusion model. The livers were perfused with media containing partially purified rat hepatic lipase or bovine milk lipoprotein lipase.
Jansen, H. (Hans) +2 more
core +1 more source
Journal of Lipid Research, 1987 3T3-L1 adipocytes were used to test the hypothesis that hormone-sensitive lipolysis and lipoprotein lipase activity might be regulated in a reciprocal manner.
S S Chernick +3 more
doaj +1 more source
The mechanism of heparin stimulation of rat adipocyte lipoprotein lipase
Journal of Lipid Research, 1969 Free fat cells and stromal-vascular cells were prepared from rat adipose tissue by incubation with collagenase. NH4OH-NH4Cl extracts of acetone-ether powders prepared from fat cells contained lipoprotein lipase activity but extracts of stromal-vascular ...
R.L. Patten, C.H. Hollenberg
doaj +1 more source
Maternal obesity is associated with the formation of small dense LDL and hypoadiponectinemia in the third trimester [PDF]
, 2013 Context: Maternal obesity is associated with high plasma triglyceride, poor vascular function, and an increased risk for pregnancy complications. In normal-weight pregnant women, higher triglyceride is associated with increased small, dense low-density ...
Brown, E.A. +9 more
core +2 more sources
Lipoprotein lipase and hepatic lipase
Journal of Lipid Research, 2003 HDL subspecies Lp(A-I) and Lp(A-I,A-II) have different anti-atherogenic potentials. To determine the role of lipoprotein lipase (LPL) and hepatic lipase (HL) in regulating these particles, we measured these enzyme activities in 28 healthy subjects with ...
Marian C. Cheung +4 more
doaj +1 more source
Moderate exercise increases affinity of large very low density lipoproteins for hydrolysis by lipoprotein lipase [PDF]
, 2015 Context: Postprandial triglyceride (TG) concentration is independently associated with cardiovascular disease risk. Exercise reduces postprandial TG concentrations but the mechanisms responsible are unclear.
Bedford, Dorothy K. +5 more
core +1 more source