Palmoplantar keratoderma along with neuromuscular and metabolic phenotypes in Slurp1-deficient mice. [PDF]
, 2014 Mutations in SLURP1 cause mal de Meleda, a rare palmoplantar keratoderma (PPK). SLURP1 is a secreted protein that is expressed highly in keratinocytes but has also been identified elsewhere (e.g., spinal cord neurons).
Adeyo, Oludotun +11 more
core +2 more sources
A rapid assay for lipoprotein lipase
Journal of Lipid Research, 1970 A rapid assay for lipoprotein lipase activity employing a (14)C-labeled substrate is described. The method is very sensitive and suitable for routine use.
R J Huebotter +3 more
openaire +4 more sources
Lipoprotein Lipase Activator NO‐1886 [PDF]
Cardiovascular Drug Reviews, 2003 ABSTRACTLipoprotein lipase (LPL) is a rate‐limiting enzyme that hydrolyzes circulating triglyceride‐rich lipoproteins such as very low‐density lipoproteins and chylomicrons. A decrease in LPL activity is associated with an increase in plasma triglycerides (TG) and a decrease in plasma high‐density lipoprotein cholesterol (HDL‐C). The increase in plasma
Kazuhiko Tsutsumi, Weidong Yin
openaire +3 more sources
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Advanced Functional Materials, EarlyView.Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth +2 more
wiley +1 more source
Association between skeletal muscle mass and serum concentrations of lipoprotein lipase, GPIHBP1, and hepatic triglyceride lipase in young Japanese men [PDF]
, 2019 学位記番号 ...
Matsumoto, Ryutaro +2 more
core
Linkage of Low-Density Lipoprotein Size to the Lipoprotein Lipase Gene in Heterozygous Lipoprotein Lipase Deficiency [PDF]
The American Journal of Human Genetics, 1999 Small low-density lipoprotein (LDL) particles are a genetically influenced coronary disease risk factor. Lipoprotein lipase (LpL) is a rate-limiting enzyme in the formation of LDL particles. The current study examined genetic linkage of LDL particle size to the LpL gene in five families with structural mutations in the LpL gene.
Gail P. Jarvik +4 more
openaire +3 more sources
Adjusting Cell‐Surface Interactions Through a Covalent Immobilization of Biomolecules
Advanced Materials Interfaces, EarlyView.This review presents an overview of current and emerging immobilization techniques coupled with an in‐depth investigation of the underlying mechanisms governing the activity and stability of covalently immobilized biomolecules. The aim of this study is to serve as a guide for the development of long‐lasting biomedical coatings with versatile biological
Sara Shakibania +2 more
wiley +1 more source
Recombinant gamma interferon induces hypertriglyceridemia and inhibits post-heparin lipase activity in cancer patients. [PDF]
, 1986 Animals suffering from malignancy or chronic infection develop characteristic metabolic abnormalities, including a well-defined hypertriglyceridemic state.
Bradley, WA +6 more
core
Influence of different fat emulsions with 10 or 20% MCT/LCT or LCT on lipoproteins in plasma of patients after abdominal surgery [PDF]
, 1998 In patients after elective abdominal surgery, different fat emulsions were used to compare their efficacy in total parenteral nutrition and in normalizing plasma lipoprotein levels.
Hailer, Susanne +2 more
core +1 more source
Advanced Science, EarlyView.This study constructs a stacked multimodal machine learning model for nonalcoholic fattly liver disease (NAFLD) by integrating genetic and clinical features, and synthesize an in‐silico quantitative marker (ISNLD) that enables personalized risk stratification for intrahepatic and extrahepatic outcomes of high‐risk individuals of NAFLD.
Lushan Xiao +14 more
wiley +1 more source