Lipoprotein lipase deficiency with pancreatitis in mink: biochemical characterization and pathology
Journal of Lipid Research, 1997 A severe hyperlipemia in mink, with a pattern that suggested recessive inheritance, was observed at a farm in Norway. On a normal mink diet, affected animals had grossly elevated levels of plasma triglycerides which decreased towards normal on a low-fat ...
B Christophersen +4 more
doaj +1 more source
Lipoprotein Lipase Activator NO‐1886 [PDF]
Cardiovascular Drug Reviews, 2003 ABSTRACTLipoprotein lipase (LPL) is a rate‐limiting enzyme that hydrolyzes circulating triglyceride‐rich lipoproteins such as very low‐density lipoproteins and chylomicrons. A decrease in LPL activity is associated with an increase in plasma triglycerides (TG) and a decrease in plasma high‐density lipoprotein cholesterol (HDL‐C). The increase in plasma
Kazuhiko Tsutsumi, Weidong Yin
openaire +3 more sources
Gene-environment interactions due to quantile-specific heritability of triglyceride and VLDL concentrations. [PDF]
, 2020 "Quantile-dependent expressivity" is a dependence of genetic effects on whether the phenotype (e.g., triglycerides) is high or low relative to its distribution in the population.
Williams, Paul T
core +1 more source
Chylomicron protein content and the rate of lipoprotein lipase activity
Journal of Lipid Research, 1976 Chylomicrons isolated from rat intestinal lymph were incubated with plasma. Protein transfer to chylomicrons, reaction rate with purified lipoprotein lipase, and content of lipase cofactor were determined.
C J Fielding, P E Fielding
doaj +1 more source
Recombinant gamma interferon induces hypertriglyceridemia and inhibits post-heparin lipase activity in cancer patients. [PDF]
, 1986 Animals suffering from malignancy or chronic infection develop characteristic metabolic abnormalities, including a well-defined hypertriglyceridemic state.
Bradley, WA +6 more
core
Plasma lipoprotein subfraction concentrations are associated with lipid metabolism and age-related macular degeneration [PDF]
, 2017 10.1194/jlr.M073684Journal of Lipid Research5891785 ...
Apte, Rajendra S. +10 more
core +2 more sources
FEBS Open Bio, EarlyView.Berberine–cinnamic acid co‐crystal (BBR‐CA) inhibits the phosphorylation of the phosphatidylinositol 3‐kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway, suppressing the transfer of pre‐sterol regulatory element‐binding proteins‐1 (SREBP‐1) from the endoplasmic reticulum to the nucleus. This results in a decrease in the expression level of
Wenheng Gao +7 more
wiley +1 more source
Familial chylomicronemia due to a circulating inhibitor of lipoprotein lipase activity
Journal of Lipid Research, 1983 A mother and her son who have lipoprotein phenotype I are described. They differed from subjects with lipoprotein lipase deficiency in that lipoprotein lipase was present in adipose tissue respectively at 30- and 2-fold the levels seen in normal subjects,
J D Brunzell +7 more
doaj +1 more source
Association between skeletal muscle mass and serum concentrations of lipoprotein lipase, GPIHBP1, and hepatic triglyceride lipase in young Japanese men [PDF]
, 2019 学位記番号 ...
Matsumoto, Ryutaro +2 more
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The Carboxyl-Terminal Segment of Apolipoprotein A-V Undergoes a Lipid-Induced Conformational Change [PDF]
, 2010 Apolipoprotein (apo) A-V is a 343-residue, multidomain protein that plays an important role in regulation of plasma triglyceride homeostasis. Primary sequence analysis revealed a unique tetraproline sequence (Pro293-Pro296) near the carboxyl terminus of ...
Lee, B. L. +4 more
core +2 more sources