Editorial: Chronic inflammation, oxidative stress and lipoprotein metabolism in cardio-pulmonary continuum. [PDF]
Sorokin AV +3 more
europepmc +1 more source
Generating golden Syrian hamsters with conditional alleles via zygote microinjection of CRISPR/Cas9
We established the first conditional knockout (cKO) model in the golden Syrian hamster by CRISPR/Cas9‐mediated genome editing. Cas9 protein, two sgRNAs, and a donor plasmid carrying loxP‐flanked exon 2 of the ApoF gene were microinjected into one‐cell embryos. The floxed allele was efficiently generated (up to 27%) and transmitted through the germline.
Wei Chen +16 more
wiley +1 more source
Correction: Bioinformatic analysis identifies LPL as a critical gene in diabetic kidney disease via lipoprotein metabolism. [PDF]
Dong Q, Xu H, Xu P, Liu J, Shen Z.
europepmc +1 more source
Impact of Sepsis on High-Density Lipoprotein Metabolism. [PDF]
Reisinger AC +6 more
europepmc +1 more source
Quantitative proteomics identifies clusterin as a novel biomarker for atherosclerosis
This schematic illustrates the proposed mechanism. In advanced atherosclerotic lesions, upregulated CLU on the cell surface activates low‐density lipoprotein (LDL) receptor‐related protein 1 (LRP1). This interaction triggers the phosphorylation and activation of AKT.
Dengfeng Ding +10 more
wiley +1 more source
Hepatic Lipoprotein Metabolism: Current and Future In Vitro Cell-Based Systems. [PDF]
Kiss I +5 more
europepmc +1 more source
Apolipoprotein F is reduced in humans with steatosis and controls plasma triglyceride-rich lipoprotein metabolism. [PDF]
Deprince A +30 more
europepmc +1 more source
Objective Identifying modifiable factors influencing amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) risk is important for prevention. Blood biomarkers, particularly cholesterol, have been associated with neurodegenerative risk, but findings in ALS are inconsistent, and data on FTD are limited.
Christos V. Chalitsios +5 more
wiley +1 more source
Bioinformatic analysis identifies LPL as a critical gene in diabetic kidney disease via lipoprotein metabolism. [PDF]
Dong Q, Xu H, Xu P, Liu J, Shen Z.
europepmc +1 more source

