Results 161 to 170 of about 244,000 (301)

Ixekizumab With Tirzepatide Achieved Greater Disease Control Than Ixekizumab Alone in Adults With Psoriatic Arthritis and Overweight or Obesity: Results From a Randomized Clinical Trial

Arthritis &Rheumatology, EarlyView.
Objective Overweight or obesity is prevalent in 72% to 82% of individuals with psoriatic arthritis (PsA). We assessed the efficacy and safety of ixekizumab (IXE) concomitantly administered with tirzepatide (TZP) compared with IXE alone in adult participants with active PsA and overweight with at least one weight‐related comorbidity or obesity.
Joseph F. Merola, Philip Mease, Alan Kivitz, Naveed Sattar, Laura C. Coates, Daniel Aletaha, Cynthia E. Kartman, Peter Fischer, Luna Sun, Píndaro Martínez‐Osuna, Andris Kronbergs, Purvi Prajapati, Anabela Cardoso, Mark C. Genovese, Alexis Ogdie   +14 more
wiley   +1 more source

Lipoprotein Metabolism in Hematological Malignancies: A Role in Shaping the Tumor Cell Microenvironment? [PDF]

Metabolites
Sellam M, Lambert M, Varin-Blank N, Saitoski K.   +3 more
europepmc   +1 more source

Role of apolipoprotein C1 in lipoprotein metabolism, atherosclerosis and diabetes: a systematic review. [PDF]

Cardiovasc Diabetol, 2022
Rouland A, Masson D, Lagrost L, Vergès B, Gautier T, Bouillet B.   +5 more
europepmc   +1 more source

T cells, the Next Big Target in Axial Spondyloarthritis?

Arthritis &Rheumatology, EarlyView.
Axial spondyloarthritis (axSpA) is a chronic inflammatory disease characterized by complex immune dysregulation, with T cells playing a central role in its pathogenesis. In this review, we synthesize current knowledge on diverse T cell subsets in axSpA, their pathogenic mechanisms, and emerging therapeutic strategies targeting these cells. We highlight
Mansi K. Aparnathi, Nigil Haroon
wiley   +1 more source

Tomatoes, lysophosphatidic acid, and the small intestine: new pieces in the puzzle of apolipoprotein mimetic peptides?1

Journal of Lipid Research, 2013
A.T. Remaley
doaj   +1 more source

From lipoprotein metabolism to blood clotting: Highlights of the 2025 Fredrickson lipid research conference. [PDF]

J Lipid Res
Smith AN, Beg MA, Hur WS, Ginsburg D, Kullo IJ, Davies SS, Tabas I, Williams JW, Mineo C, Cai B, Gupta RK, Amengual J, Schwendeman A, Graf GA, Sorci Thomas M, Zheng Z.   +15 more
europepmc   +1 more source

Seasonal Factors Are Associated with Activities of Enzymes Involved in High-Density Lipoprotein Metabolism among Pregnant Females in Ghana. [PDF]

Curr Dev Nutr, 2023
Hong BV, Zheng JJ, Romo EZ, Agus JK, Tang X, Arnold CD, Adu-Afarwuah S, Lartey A, Okronipa H, Dewey KG, Zivkovic AM.   +10 more
europepmc   +1 more source

Postprandial lipoprotein metabolism in diabetes

, 2001
THESIS 6438Cardiovascular disease is up to four times greater in patients with Type 2 diabetes compared with nonnoglycaemic individuals (Pyorala et al., 1987; Laakso and Lehto 1997).
Phillips, Catherine Mary
core  

Biomaterial design strategies for enhancing mitochondrial transplantation therapy

BMEMat, EarlyView.
Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang, Yushan Zhang, Hang Li, Sirui Peng, Donghao Lyu, Chunxiao Zhou, Sheng Ding, Zujian Feng, Pingsheng Huang, Chuangnian Zhang, Hongjun Wang, Deling Kong, Weiwei Wang   +12 more
wiley   +1 more source

Impact of mRNA and protein isoforms in lipoprotein metabolism and how to modulate them. [PDF]

Curr Opin Lipidol
Martinovich KM, Cale JM, Aung-Htut MT.
europepmc   +1 more source