ABSTRACT Although sphingolipids are key players in lipotoxicity and metabolic diseases, their response to bariatric surgery and their relation to metabolic improvement remain unclear. This pilot study investigated plasma sphingolipid remodeling after Roux‐en‐Y gastric bypass (RYGB) and its associations with clinical and biochemical markers of ...
Gabriela de Oliveira Lemos +3 more
wiley +1 more source
Orthogonal Investigation at Single-Particle and Ensemble Levels Uncovers Lipoprotein-Extracellular Vesicle Binding. [PDF]
Musicò A +12 more
europepmc +1 more source
ABSTRACT This study aimed to explore the differences of peripheral blood (PB) and bone marrow serum lipidomic profiles in severe aplastic anemia (SAA) patients and their significance in predicting earlier immunosuppressive therapy (IST) response. A cohort of 11 newly diagnosed SAA patients and 15 healthy controls were enrolled between June 2020 and ...
Zexing Sun +11 more
wiley +1 more source
Serum HDL subfractions are impaired by COVID-19 vaccine in patients with thymic epithelial tumors. [PDF]
Cernera G +7 more
europepmc +1 more source
ABSTRACT Circadian rhythms orchestrate cardiovascular physiology by regulating immune and inflammatory pathways. Disruption of these rhythms profoundly alters vascular homeostasis, thereby promoting the onset and progression of cardiovascular diseases (CVD).
Tian Zhang +22 more
wiley +1 more source
Enhanced Qualities of High-Density Lipoproteins (HDLs) with Antioxidant Abilities Are Associated with Lower Susceptibility of Hypertension in Middle-Aged Korean Participants: Impaired HDL Quality and Hypertension Risk. [PDF]
Cho KH +4 more
europepmc +1 more source
High-Density Lipoproteins: Nature's Multifunctional Nanoparticles.
Rui Kuai +4 more
semanticscholar +1 more source
Nanoformulated Diacerein Alleviates Hyperlipidemia via Gut Microbiota Modulation In Vivo
A nanoformulation of diacerein (Nano‐DIA) was fabricated with carboxymethyl cellulose, achieving enhanced solubility and rapid dissolution for alternative anti‐hyperlipidemia therapeutics. Mechanistic studies revealed its in vivo lipid‐lowering efficacy is through metabolite‐mediated and microbiota‐dependent manner, highlighting its dual action on host
Zheng Peng +8 more
wiley +1 more source
APOE-containing HDL: A New Window into the HDL Function and Atherosclerosis Progression. [PDF]
Nohara A.
europepmc +1 more source
Intracellular cholesterol transporters and modulation of hepatic lipid metabolism: implications for diabetic dyslipidaemia and steatosis [PDF]
Caridis, Anna-Maria +3 more
core +1 more source

