Results 281 to 290 of about 494,667 (340)

Low‐Density Lipoproteins, High‐Density Lipoproteins (HDL), and HDL‐Associated Proteins Differentially Modulate Chronic Myelogenous Leukemia Cell Viability

Lipids, 2020
AbstractCellular lipid metabolism, lipoprotein interactions, and liver X receptor (LXR) activation have been implicated in the pathophysiology and treatment of cancer, although findings vary across cancer models and by lipoprotein profiles. In this study, we investigated the effects of human‐derived low‐density lipoproteins (LDL), high‐density ...
Catherine J. Andersen, Lydia Dupree, Kristina Murray, Nicholas Ragonesi, Kaley McMullen, Layra Cintrón‐Rivera, Adam Doerr   +6 more
openaire   +2 more sources

The interaction of lipolysis products of very low density lipoprotein with plasma high density lipoprotein (HDL): perfusate HDL with plasma HDL subfractions

Biochemistry and Cell Biology, 1987
The nature of the interaction of high density lipoproteins (HDL), formed during lipolysis of human very low density lipoprotein (VLDL) by perfused rat heart, with subfractions of human plasma HDL was investigated. Perfusate HDL, containing apoliproproteins (apo) E, C-II, and C-III but no apo A-I or A-II, was incubated with a subfraction of HDL (HDL-A)
S P, Tam, W C, Breckenridge
openaire   +2 more sources

Metabolismus und Funktion der Lipoproteine hoher Dichte (HDL)

Praxis, 2019
Zusammenfassung. HDL wurde lange Zeit als das «gute Cholesterin» angesehen, das für die Gesundheit des Gesamtorganismus und speziell des kardiovaskulären Systems essenziell ist. HDL ist jedoch komplex aufgebaut und durchläuft dynamische Umbauprozesse, an dem zahlreiche Komponenten, Enzyme und verschiedene Gewebe beteiligt sind.
Jomard, Anne, Osto, Elena
openaire   +1 more source

Degradation of High-Density Lipoproteins (HDL) In Vitro

Scandinavian Journal of Clinical and Laboratory Investigation, 1974
An isolation procedure is described in which, in the presence of a SH-blocking agent, DTNB, LP-B, and albumin-free HDL2 and HDL3 were isolated. Subfractionation on hydroxylapatite column chromatography of HDL2 and HDL3 respectively, gave three parent fractions of characteristic polypeptide composition.
S O, Olofsson, A, Gustafson
openaire   +2 more sources

High-density Lipoprotein (HDL) Dysfunction and the Future of HDL

Current Vascular Pharmacology, 2018
Although High Density Lipoprotein Cholesterol (HDL-C) levels are inversely proportional to cardiovascular risk in many studies, recent pharmacological interventional studies with HDL-C raising strategies did not show a benefit in terms of vascular events. The HDL particle is heterogenous with anti-atherogenic functions and non-vascular effects.
openaire   +2 more sources

High Density Lipoprotein (HDL) Metabolism in Noninsulin-Dependent Diabetes Mellitus: Measurement of HDL Turnover Using Tritiated HDL*

The Journal of Clinical Endocrinology & Metabolism, 1987
High density lipoprotein (HDL) kinetics were studied by injecting [3H]apoprotein A-I (apoA-I)/HDL into 12 subjects with normal glucose tolerance and 12 patients with noninsulin-dependent diabetes mellitus (NIDDM). The results indicate that the mean fractional catabolic rate (FCR) of apoA-I/HDL was significantly faster [0.63 +/- 0.07 (+/- SEM) vs. 0.39 +
A, Golay, L, Zech, M Z, Shi, Y A, Chiou, G M, Reaven, Y D, Chen   +5 more
openaire   +2 more sources

HDL-binding lipoproteins on human fetal hepatocytes

Bulletin of Experimental Biology and Medicine, 1998
Two types of binding sites for high-density lipoproteins (Kd=1 μg/ml and 20 μg/ml) were identified on human fetal hepatocytes and designated as P1 and P2. Ligand blotting has shown that P1 site is protein with Mr 100 kD and P2 site involves two proteins with Mr 105 and 110 kD.
A. V. Bocharov, T. G. Vishnyakova, I. N. Baranova, V. S. Repin, M. A. Kornyushin, L. N. Kask, G. T. Sukhikh, Yu. A. Blidchenko, M. V. Eremeeva   +8 more
openaire   +1 more source

Non-HDL-cholesterol and apolipoprotein B compared with LDL-cholesterol in atherosclerotic cardiovascular disease risk assessment.

Pathology (Sydney), 2019
Low density lipoprotein (LDL) is the predominant atherogenic lipoprotein particle in the circulation. Conventionally, a fasting lipid profile has been used for atherosclerotic cardiovascular disease (ASCVD) risk assessment.
Stuart S Carr, A. Hooper, D. Sullivan, J. Burnett   +3 more
semanticscholar   +1 more source

Monocyte‐to‐HDL‐cholesterol ratio as a prognostic marker in cardiovascular diseases

Journal of Cellular Physiology, 2018
Inflammation and lipid accumulation are two basic hallmarks of atherosclerosis as a chronic disease. Inflammation not only is a local response but can also be considered as a systemic process followed by an elevation of inflammatory mediators.
S. Ganjali, A. Gotto, M. Ruscica, S. Atkin, A. Butler, M. Banach, A. Sahebkar   +6 more
semanticscholar   +1 more source

Cholesterol, High Density Lipoprotein‐Cholesterol (HDL) and Cholesterol/HDL‐ratio Versus Arterial Blood Pressure.

Acta Medica Scandinavica, 1981
Abstract: In a cardiovascular survey of 928 men and women aged exactly 30, 40, 50 & 60 years, a correlation between serum cholesterol, cholesterol/HDL‐ratio and arterial blood pressure was found. This correlation was indirectly caused by mutual correlations to relative weight and age as a final result found after multiple rank correlation analysis
E, Agner, H I, Mørck, T, Brendstrup, H, Hollnagel, M, Schroll, F, Gyntelberg   +5 more
openaire   +2 more sources