Results 261 to 270 of about 66,086 (315)
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Circulating low density lipoprotein (LDL)
Hormone Molecular Biology and Clinical Investigation, 2018Abstract Low-density lipoprotein (LDL) particles are known as atherogenic agents in coronary artery diseases. They modify to other electronegative forms and may be the subject for improvement of inflammatory events in vessel subendothelial spaces. The circulating LDL value is associated with the plasma PCSK-9 level.
Mohsen, Khosravi +2 more
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Low density lipoprotein (LDL) binding affinity for the LDL receptor in hyperlipoproteinemia
Atherosclerosis, 1999We measured the binding affinity of low density lipoprotein (LDL) for the LDL receptor in patients with various types of hyperlipoproteinemia and investigated the effects of LDL lipid composition and particle size on receptor affinity. LDL (1.019 < d < 1.063) was isolated by sequential ultracentrifugation from the serum of normolipidemic controls and ...
Y, Toyota +3 more
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Low-density lipoprotein (LDL) oxidizability before and after LDL apheresis
Metabolism, 1999Oxidation of low-density lipoprotein (LDL) plays a major role in the development of atherosclerosis. Hypercholesterolemia has been associated with enhanced in vitro oxidation of LDL, and lipid-lowering therapy reduces LDL oxidizability. In the present study, we investigated whether LDL apheresis performed with different techniques affects in vitro ...
M G, Donner +3 more
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The Role of the LDL Receptor in Lipoprotein Metabolism
1987The discovery of the LDL receptor in cultured mammalian cells by Goldstein and Brown in 1973 was followed by a rapid increase in our understanding of cellular and total body cholesterol metabolism1. The LDL receptor is the starting point for an intracellular pathway which is of fundamental importance in regulating cellular cholesterol metabolism ...
D W, Bilheimer, S M, Grundy
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The lipoproteins selections aphereses with LDL Lipopak 400
Transfusion and Apheresis Science, 2013The lipid lowering is one of the main ways to achieve reduction of the atherosclerosis progress. In the rare patients with homozygous familial hypercholesterolemia low density lipoprotein cholesterol apheresis should be performed as these patients usually have extremely high low density lipoprotein cholesterol concentrations and these patients usually ...
A, Griskevicius +4 more
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Are ‘precipitated LDL’ really low density lipoproteins?
Clinica Chimica Acta, 1987Cholesterol, phospholipid and Apo B levels were determined in low density lipoproteins (LDL) precipitated by amphipathic polymers (Biomérieux kit, Marcy-l'Etoile, France) and compared to those of ultracentrifuged LDL. For 113 sera (triglyceride level less than 4.5 mmol/l, absence of very low density lipoproteins-remnants) LDL-cholesterol values were ...
F, Mainard, Y, Madec
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Lipoprotein correlates of LDL particle size
Atherosclerosis, 2000Correlations of low-density lipoprotein (LDL) predominant particle diameters (PPD) were investigated in samples taken from the San Antonio Family Heart Study. A frequency histogram showed LDL PPD occurs in at least two distinct modes, at about 25.5 and 26.9 nm, with the nadir at about 26.2 nm.
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A New Low Density Lipoprotein (LDL) Adsorbent
Artificial Cells, Blood Substitutes, and Biotechnology, 1997Crosslinked O-Carboxymethyl (O-CM) Chitosan beads were prepared by the reaction of O-CM Chitosan with glutaraldehyde solution. Results in vitro experiments with this new developed LDL adsorbent are presented. This adsorbent is capable of cutting down LDL-Cholesterol without significantly affecting HDL and TP (Total Proteins) levels in the plasma.
Y U, Yihua, H E, Binglin
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Atherosclerosis, 1999
The changes in low density lipoprotein (LDL) composition and oxidizability after LDL-apheresis (LA) using dextran sulfate cellulose columns were evaluated in 12 hypercholesterolemic men (mean+/-S.D. total cholesterol (TC) 9.7+/-1.8 mmol/l). After 10-20 months on biweekly LA combined with simvastatin 40 mg per day immediate pre-apheresis levels of TC ...
Kroon, A.A. +3 more
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The changes in low density lipoprotein (LDL) composition and oxidizability after LDL-apheresis (LA) using dextran sulfate cellulose columns were evaluated in 12 hypercholesterolemic men (mean+/-S.D. total cholesterol (TC) 9.7+/-1.8 mmol/l). After 10-20 months on biweekly LA combined with simvastatin 40 mg per day immediate pre-apheresis levels of TC ...
Kroon, A.A. +3 more
openaire +3 more sources