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A New Low Density Lipoprotein (LDL) Adsorbent
Artificial Cells, Blood Substitutes, and Biotechnology, 1997Crosslinked O-Carboxymethyl (O-CM) Chitosan beads were prepared by the reaction of O-CM Chitosan with glutaraldehyde solution. Results in vitro experiments with this new developed LDL adsorbent are presented. This adsorbent is capable of cutting down LDL-Cholesterol without significantly affecting HDL and TP (Total Proteins) levels in the plasma.
Binglin He, Yihua Yu
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Lipoprotein correlates of LDL particle size
Atherosclerosis, 2000Correlations of low-density lipoprotein (LDL) predominant particle diameters (PPD) were investigated in samples taken from the San Antonio Family Heart Study. A frequency histogram showed LDL PPD occurs in at least two distinct modes, at about 25.5 and 26.9 nm, with the nadir at about 26.2 nm.
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Are ‘precipitated LDL’ really low density lipoproteins?
Clinica Chimica Acta, 1987Cholesterol, phospholipid and Apo B levels were determined in low density lipoproteins (LDL) precipitated by amphipathic polymers (Biomérieux kit, Marcy-l'Etoile, France) and compared to those of ultracentrifuged LDL. For 113 sera (triglyceride level less than 4.5 mmol/l, absence of very low density lipoproteins-remnants) LDL-cholesterol values were ...
Francine Mainard, Yves Madec
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Atherosclerosis, 1999
The changes in low density lipoprotein (LDL) composition and oxidizability after LDL-apheresis (LA) using dextran sulfate cellulose columns were evaluated in 12 hypercholesterolemic men (mean+/-S.D. total cholesterol (TC) 9.7+/-1.8 mmol/l). After 10-20 months on biweekly LA combined with simvastatin 40 mg per day immediate pre-apheresis levels of TC ...
Kroon, A.A. +3 more
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The changes in low density lipoprotein (LDL) composition and oxidizability after LDL-apheresis (LA) using dextran sulfate cellulose columns were evaluated in 12 hypercholesterolemic men (mean+/-S.D. total cholesterol (TC) 9.7+/-1.8 mmol/l). After 10-20 months on biweekly LA combined with simvastatin 40 mg per day immediate pre-apheresis levels of TC ...
Kroon, A.A. +3 more
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The rebound of lipoproteins after LDL-apheresis. Kinetics and estimation of mean lipoprotein levels
Atherosclerosis, 2000We studied the rebound of lipoproteins in 20 hypercholesterolemic men [mean total cholesterol (TC) levels 9.6+/-1.8 mmol/l] after LDL-apheresis (LA) to determine the rate of recovery and the change in cholesterol synthesis, and to find a uniform estimation for time-averaged levels.
Kroon, A.A. +3 more
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Nanomatertials as Low Density Lipoprotein (LDL) Sensors [PDF]
MRS Proceedings, 2004 ABSTRACTIn2O3nanowire and carbon nanotube transistors were used to study the chemical gating effects in response to LDL particles. Low density lipoprotein (LDL) cholesterol in blood constitutes a risk factor for coronary artery disease (heart attack). The interactions of LDL particles with these two different surfaces were investigated.
Tzung K. Hsiai +7 more
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Assaying Low-Density-Lipoprotein (LDL) Uptake into Cells
2017Determination of LDL particle uptake into cells is a valuable technique in the field of cholesterol metabolism. This allows assessment of LDL uptake capacity in different adherent and non-adherent cells types, as well as the effect of cellular, genetic, or pharmacological perturbations on this process. Here, we detail a general procedure that describes
Anke Loregger +2 more
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Autoantibodies against oxidized low-density lipoprotein (ox-LDL) and LDL oxidation status
Clinical Chemistry and Laboratory Medicine (CCLM), 2004AbstractOxidized low-density lipoproteins (ox-LDLs) and their autoantibodies (OLAB) are involved in the development of atherosclerosis in animal models, but their role in humans is still not clear. For this reason we studied 54 patients with β-thalassemia major (TM), as a model of chronically low circulating LDLs with a high level of oxidation; 44 ...
Brizzi P +7 more
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Effect of gemfibrozil on composition of lipoproteins and distribution of LDL subspecies
Atherosclerosis, 1992We studied the effect of gemfibrozil on the compositions of VLDL, LDL and distribution of LDL subspecies in type II hyperlipidemic patients. Gemfibrozil significantly lowered serum triglyceride levels in this group of patients who had normal to moderately elevated triglyceride prior to therapy.
Michael Y. Tsai +2 more
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Low-Density Lipoprotein (LDL) Apheresis
2015Low-density lipoprotein (LDL) apheresis, also referred to as lipoprotein apheresis or lipid apheresis, is a procedure that involves extracorporeal treatment of plasma to remove apoprotein (apo) B-containing lipoproteins followed by reinfusion of the processed blood.
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