Results 31 to 40 of about 462,380 (329)

Low-density lipoproteins cause atherosclerotic cardiovascular disease. 1. Evidence from genetic, epidemiologic, and clinical studies. A consensus statement from the European Atherosclerosis Society Consensus Panel

European Heart Journal, 2017
Aims To appraise the clinical and genetic evidence that low-density lipoproteins (LDLs) cause atherosclerotic cardiovascular disease (ASCVD). Methods and results We assessed whether the association between LDL and ASCVD fulfils the criteria for causality
B. Ference, H. Ginsberg, I. Graham, K. Ray, C. Packard, E. Bruckert, R. Hegele, R. Krauss, F. Raal, H. Schunkert, G. Watts, J. Borén, S. Fazio, J. Horton, L. Masana, S. Nicholls, B. Nordestgaard, B. Nordestgaard, B. Sluis, M. Taskinen, L. Tokgozoglu, Ulf Landmesser, Ulf Landmesser, Ulf Landmesser, U. Laufs, Olov Wiklund, Olov Wiklund, Jane K. Stock, M. Chapman, A. Catapano   +29 more
semanticscholar   +1 more source

Analytical capillary isotachophoresis of total plasma lipoproteins: a new tool to identify atherogenic low density lipoproteins

Journal of Lipid Research, 1999
Plasma low density lipoproteins from 20 patients were separated by capillary isotachophoresis (ITP). In each patient the apparent diameter of the predominant LDL peak on whole plasma was also determined by nondenaturing gradient gel electrophoresis ...
Gabriele Bittolo-Bon, Giuseppe Cazzolato
doaj   +1 more source

An integrated mathematical model of cellular cholesterol biosynthesis and lipoprotein metabolism [PDF]

, 2018
Cholesterol regulation is an important aspect of human health. In this work we bring together and extend two recent mathematical models describing cholesterol biosynthesis and lipoprotein endocytosis to create an integrated model of lipoprotein ...
Pool, Frances, Sweby, Peter K., Tindall, Marcus J.   +2 more
core   +2 more sources

Quantitation of the in vitro free cholesterol exchange of human red cells and lipoproteins

Journal of Lipid Research, 1970
The exchange of free cholesterol in vitro between human red blood cells and low density lipoproteins (LDL) was quantified. The flux of sterol between LDL and red cells was relatively constant over a wide range of concentrations of free cholesterol in ...
STEVEN H. QUARFORDT, HELEN L. HILDERMAN
doaj   +1 more source

Unpacking and understanding the impact of proprotein convertase subtilisin/kexin type 9 inhibitors on apolipoprotein B metabolism [PDF]

, 2017
No abstract ...
Packard, Chris J.
core   +1 more source

Hepatitis C virus relies on lipoproteins for its life cycle [PDF]

, 2016
Hepatitis C virus (HCV) infects over 150 million people worldwide. In most cases, HCV infection becomes chronic causing liver disease ranging from fibrosis to cirrhosis and hepatocellular carcinoma.
Alonzi, Tonino, DI CAPRIO, Giorgia, Fimia, Gian Maria, Grassi, Germana, Ippolito, Giuseppe, Tripodi, Marco   +5 more
core   +1 more source

Regulation of lipid transfer between lipoproteins by an endogenous plasma protein: selective inhibition among lipoprotein classes.

Journal of Lipid Research, 1994
Lipid transfer protein (LTP) remodels plasma lipoproteins by promoting mass transfers of cholesteryl ester (CE) and triglyceride between lipoproteins.
R E Morton, D J Greene
doaj   +1 more source

Maternal obesity is associated with the formation of small dense LDL and hypoadiponectinemia in the third trimester [PDF]

, 2013
Context: Maternal obesity is associated with high plasma triglyceride, poor vascular function, and an increased risk for pregnancy complications. In normal-weight pregnant women, higher triglyceride is associated with increased small, dense low-density ...
Brown, E.A., Caslake, M.J., Cooney, J., Freeman, D.J., Griffin, B.A., Meyer, B.J., Nilsson, S., Olivecrona, G., Ramsay, J.E., Stewart, F.M.   +9 more
core   +2 more sources

Familial cholesteryl ester transfer protein deficiency is associated with triglyceride-rich low density lipoproteins containing cholesteryl esters of probable intracellular origin.

Journal of Lipid Research, 1991
The net transfer of core lipids between lipoproteins is facilitated by cholesteryl ester transfer protein (CETP). We have recently documented CETP deficiency in a family with hyperalphalipoproteinemia, due to a CETP gene splicing defect.
CL Bisgaier, MV Siebenkas, ML Brown, A Inazu, J Koizumi, H Mabuchi, AR Tall   +6 more
doaj   +1 more source

HDL and LDL: Potential New Players in Breast Cancer Development

Journal of Clinical Medicine, 2019
Breast cancer is the most prevalent cancer and primary cause of cancer-related mortality in women. The identification of risk factors can improve prevention of cancer, and obesity and hypercholesterolemia represent potentially modifiable breast cancer ...
L. Cedó, S. Reddy, E. Mato, F. Blanco-Vaca, J. Escolà-Gil   +4 more
semanticscholar   +1 more source