Results 111 to 120 of about 285,687 (237)

Efficacy and safety of once‐weekly tirzepatide in Japanese participants with type 2 diabetes who have obesity or overweight: Subpopulation analysis of the SURMOUNT‐2 trial

Diabetes, Obesity and Metabolism, Volume 27, Issue 8, Page 4557-4566, August 2025.
Abstract Aim To assess the efficacy and safety of once‐weekly tirzepatide in Japanese participants with obesity and type 2 diabetes (T2D). Materials and Methods This subpopulation analysis of 41 Japanese participants from three clinical trial sites in the SURMOUNT‐2 trial evaluated the efficacy and safety of tirzepatide as an adjunct to lifestyle ...
Toshimasa Yamauchi, Taro Asakura, Tomotaka Shingaki, Tomonori Oura, Hideki Katagiri   +4 more
wiley   +1 more source

Pathogenesis of the hypertriglyceridemia at early stages of alcoholic liver injury in the baboon.

Journal of Lipid Research, 1990
To study the mechanism of alcoholic hypertriglyceridemia, baboons were pair-fed liquid diets containing 50% of energy as ethanol or as additional carbohydrate for 5-16 months.
M J Savolainen, E Baraona, M A Leo, C S Lieber   +3 more
doaj  

Bridging the gap in obesity research: A consensus statement from the European Society for Clinical Investigation

European Journal of Clinical Investigation, Volume 55, Issue 8, August 2025.
This consensus highlights critical research gaps in obesity epidemiology, phenotypic heterogeneity and clinical management, calling for advanced methodologies, collaborative strategies and innovative policies to mitigate the global obesity epidemic and its socio‐economic impacts.
Federico Carbone, Jean‐Pierre Després, John P. A. Ioannidis, Ian J. Neeland, Gabriella Garruti, Luca Busetto, Luca Liberale, Stefano Ministrini, Gemma Vilahur, Thomas H. Schindler, Maria Paula Macedo, Agostino Di Ciaula, Marcin Krawczyk, Andreas Geier, Gyorgy Baffy, Maria Felicia Faienza, Ilaria Farella, Nicola Santoro, Gema Frühbeck, Patricia Yárnoz‐Esquiroz, Javier Gómez‐Ambrosi, Emma Chávez‐Manzanera, Verónica Vázquez‐Velázquez, Jean‐Michel Oppert, Dimitrios N. Kiortsis, Paolo Sbraccia, Carmine Zoccali, Piero Portincasa, Fabrizio Montecucco   +28 more
wiley   +1 more source

Secretion of lipids, apolipoproteins, and lipoproteins by human hepatoma cell line, HepG2: effects of oleic acid and insulin

Journal of Lipid Research, 1987
The aim of this study was to determine the effect of oleic acid and insulin on the secretion of lipoproteins by HepG2 cells grown in minimum essential medium.
N Dashti, G Wolfbauer
doaj  

Transabdominal photobiomodulation applications: A systematic review and meta‐analysis

Obesity Reviews, Volume 26, Issue 8, August 2025.
Summary Introduction The escalating prevalence of obesity presents a multifaceted challenge involving genetic, environmental, and behavioral factors, with significant public health implications. Photobiomodulation (PBM) may positively influence metabolic activities in adipose cells and regulate inflammation, potentially impacting obesity.
Ana M. Jiménez‐García, Candela Zorzo, Alba Gutiérrez‐Menéndez, Jorge L. Arias, Natalia Arias   +4 more
wiley   +1 more source

Nascent lipoproteins from recirculating and nonrecirculating liver perfusions and from the hepatic Golgi apparatus of African green monkeys

Journal of Lipid Research, 1987
Perfusate apoB-100-containing lipoproteins from the isolated, perfused livers of African green monkeys consist of significant amounts of d greater than 1.006 g/ml particles in addition to very low density lipoproteins (VLDL).
F L Johnson, L L Swift, L L Rudel
doaj  

Defective lymphatic vasculature in obesity

Obesity Reviews, Volume 26, Issue 8, August 2025.
Summary Lymphedema is an important, and often underdiagnosed complication of obesity and is likely due to acquired defects in the lymphatic vasculature. Study of diet‐induced obesity animal models have indicated defective lymphatic vasculatures might extend to other anatomical sites, especially visceral depots.
Jingjing Zhu, John P. H. Wilding, Ji Hu
wiley   +1 more source

Characterization of very low density lipoproteins and intermediate density lipoproteins of normo- and hyperlipidemic apolipoprotein E-2 homozygotes.

Journal of Lipid Research, 1985
Triglyceride-rich lipoproteins derived from ten normo- and hyperlipidemic apoE-2 homozygotes were analyzed for their composition, beta-VLDL content, and their ability to induce cholesteryl ester storage in macrophages.
G Schmitz, G Assmann, J Augustin, A Dirkes-Kersting, B Brennhaüsen, C Karoff   +5 more
doaj  

Surface Engineering of Thrombus‐Targeting Nanocarriers for Cardiovascular Diseases: A Short Review

Advanced Materials Interfaces, Volume 12, Issue 13, July 14, 2025.
This paper systematically introduces surface modification strategies for thrombus‐targeting nanocarriers, highlights the clinical significance of nanocarrier‐based thrombolysis therapies, and prospects the synergy of combing thrombolysis and anti‐inflammatory therapies for enhanced therapeutic effect.
Xinyue Ge, Lei Ding, Wenjun Zhao, Bohan Cui, Xiang Guan, Mingfei Pan, Qingguo Li, Ning Gu   +7 more
wiley   +1 more source

Interaction of cholesterol ester and triglyceride in human plasma very low density lipoprotein1

Journal of Lipid Research, 1977
The properties of human plasma very low density lipoproteins (VLDL), low density lipoproteins (LDL), and their extracted lipids were compared using calorimetric, X-ray scattering, and polarizing microscopy techniques.
R J Deckelbaum, A R Tall, D M Small
doaj