Results 121 to 130 of about 284,504 (254)
Plasma very low density lipoproteins contain a single molecule of apolipoprotein B
Rat and human very low density lipoproteins (VLDL) were fractionated by zonal ultracentrifugation, yielding sharply defined fractions with narrow sedimentation limits.
J Elovson+7 more
doaj
Abstract In India, the increasing prevalence of diabetes and obesity poses a significant threat towards a surge in the incidence of metabolic dysfunction‐associated steatotic liver disease (MASLD), formerly known as non‐alcoholic fatty liver disease (NAFLD).
Abdul Hamid Zargar+29 more
wiley +1 more source
This consensus highlights critical research gaps in obesity epidemiology, phenotypic heterogeneity and clinical management, calling for advanced methodologies, collaborative strategies and innovative policies to mitigate the global obesity epidemic and its socio‐economic impacts.
Federico Carbone+28 more
wiley +1 more source
Alpha-tocopherol is secreted from rat liver in very low density lipoproteins
Three separate studies were carried out to test the hypothesis that rat liver secretes vitamin E (alpha-tocopherol) within very low density lipoproteins (VLDL).
W Cohn, F Loechleiter, F Weber
doaj
Pathways-driven Sparse Regression Identifies Pathways and Genes Associated with High-density Lipoprotein Cholesterol in Two Asian Cohorts [PDF]
Standard approaches to analysing data in genome-wide association studies (GWAS) ignore any potential functional relationships between genetic markers. In contrast gene pathways analysis uses prior information on functional structure within the genome to identify pathways associated with a trait of interest. In a second step, important single nucleotide
arxiv
This study examined the association between 20‐year atherosclerotic cardiovascular disease (ASCVD) risk and discordance among apolipoprotein B100 (apoB) and lipid biomarkers, using established thresholds. ApoB strongly correlated with LDL‐C and non‐HDL‐C, though concordance was limited.
Sofia‐Panagiota Giannakopoulou+8 more
wiley +1 more source
The effect of apoprotein E on the cellular metabolism of very low density lipoproteins (VLDL) was studied using the J-774 macrophage-like cell line as a foam cell model.
E Granot, S Eisenberg
doaj
Expanding our understanding of synucleinopathies: proteinopathy, proteinopenia, and lipidopathy
Neurodegeneration is thought to arise due to the disruption of the protein homeostasis. In synucleinopathies, alterations in the levels of functional and aggregated aSyn lead to proteinopenia and proteinopathy, respectively. aSyn and β‐glucocerebrosidase are closely linked to lipid metabolism, impacting organelle function and lipidostasis.
Manuel Flores‐León, Tiago F. Outeiro
wiley +1 more source
Secretion of apolipoproteins in very low density and high density lipoproteins by perfused rat liver
The incorporation of labeled amino acids into the peptides of very low density lipoproteins (VLDL) and high density lipoproteins (HDL) secreted by perfused rat liver was studied using a Ringer—albumin solution in the perfusate in place of serum to ...
Simon-Pierre Noel, David Rubinstein
doaj
Pathological significance of intranuclear structures in liver biopsy samples
Schematic representation of the potential significance of three distinct nuclear structures. Glycogenated nuclei reflects excessive glycogen accumulation in the hepatocytes. Nucleoplasmic lipid droplets form in the nucleus during hepatocyte injury. Cytoplasmic lipid droplets in the nucleoplasmic reticulum are suppressed when there is excessive fat ...
Norihiro Imai+15 more
wiley +1 more source