Results 141 to 150 of about 67,544 (271)
Hyperglycaemia‐driven metabolic dysfunction is associated with elevated circulating levels of the shared IL‐12/IL‐35 p35 subunit and an adverse atherogenic phenotype. These findings identify p35 as a promising biomarker of cardiovascular risk in patients with type 2 diabetes.
Tawanda M. Nyambuya +3 more
wiley +1 more source
Alterations of VLDL composition during alimentary lipemia.
Apoliprotein (apo) B-100-containing very low density lipoprotein (VLDL) particles secreted from the liver accumulate in plasma during alimentary lipemia.
Karpe, Fredrik +4 more
core
Interaction of cyclosporin A with human lipoproteins
The ultracentrifugal fractionation of human serum after previous incubation with cyclosporin A showed that, in healthy fasting individuals, 8% of cyclosporin A was found in the very low density lipoproteins (VLDL), 31% in the low density lipoproteins ...
Demetrios Sgoutas +3 more
core +1 more source
This network meta‐analysis of 4 randomized controlled trials (14,348 adults with type 2 diabetes, with or without established atherosclerotic cardiovascular disease) compared all clinically relevant doses of tirzepatide (1, 5, 10, 15 mg) against dulaglutide (0.75, 1.5, 4.5 mg).
Ahmed W. Hageen +13 more
wiley +1 more source
Myocardial metabolism of triacylglycerol-rich lipoproteins in type 2 diabetes.
Cardiac utilisation of very-low-density lipoprotein (VLDL) and chylomicrons (CM) was investigated in the ZDF rat model of type 2 diabetes, in order to define the role of triacylglycerol (TAG) metabolism in the development of contractile dysfunction ...
Niu, YG +3 more
core +1 more source
The comparative pharmacology and cardiometabolic outcomes of semaglutide, liraglutide and tirzepatide, integrating evidence from major clinical trial programs and meta‐analyses. ABSTRACT Background Cardiometabolic disorders such as type 2 diabetes mellitus (T2DM), obesity and cardiovascular disease (CVD) remain major global health challenges.
Hiba Bawadi +4 more
wiley +1 more source
Cinnamaldehyde derived from Cinnamomum species exerts multitarget anticancer effects by promoting oxidative stress, mitochondrial dysfunction, apoptosis, cell‐cycle arrest, autophagy, and epigenetic changes, and by suppressing mitogen‐activated protein kinase (MAPK), phosphoinositide 3‐kinase/protein kinase B/mechanistic target of rapamycin (PI3K/Akt ...
Gervason Moriasi +6 more
wiley +1 more source
The accumulation of the oxidized apolipoprotein, apoB-100, containing lipoproteins in the arterial wall and the progression of coronary atherosclerotic lesions in rabbits with β-VLDL and LDL hypercholesterolemia was compared.
Paul Holvoet, Désiré Collen
core +1 more source
Taurine and Metabolic Diseases: Molecular Mechanisms and Therapeutic Implications
The dietary sources of taurine, as well as its protective effects and mechanisms in metabolism‐related diseases and metabolic disorder–associated ocular and cerebral injuries. ABSTRACT Taurine (Tau) is a sulfur‐containing amino acid prevalent in animal tissues and primarily acquired through dietary sources.
Xiaojie Ma, Zhijian Rao, Lifang Zheng
wiley +1 more source
Triglyceride-rich very low-density lipoproteins (VLDL) are independently associated with insulin secretion in a multiethnic cohort of adolescents. [PDF]
Tricò D +5 more
europepmc +1 more source

