Results 11 to 20 of about 284,504 (254)

Scavenger receptor BI facilitates the metabolism of VLDL lipoproteins in vivo Published, JLR Papers in Press, October 22, 2007. [PDF]

Journal of Lipid Research, 2008
Scavenger receptor class B type I (SR-BI) functions as an HDL receptor that promotes the selective uptake of cholesteryl esters (CEs). The physiological role of SR-BI in VLDL metabolism, however, is largely unknown.
M. Van Eck, M. Hoekstra, Ruud Out, I. S. T. Bos, J. Kruijt, Reeni B. Hildebrand, T. Van Berkel   +6 more
semanticscholar   +5 more sources

Triglyceride Rich Lipoprotein -LPL-VLDL Receptor and Lp(a)-VLDL Receptor Pathways for Macrophage Foam Cell Formation

Journal of Atherosclerosis and Thrombosis, 2017
Very low-density lipoprotein (VLDL) receptor is a member of the low-density lipoprotein (LDL) receptor family. It binds triglyceride rich lipoprotein (TGRL) but not LDL, because it recognizes apolipoprotein (apo)E only but not apoB.
Sadao Takahashi
semanticscholar   +5 more sources

ApoAV Reduces Plasma Triglycerides by Inhibiting Very Low Density Lipoprotein-Triglyceride (VLDL-TG) Production and Stimulating Lipoprotein Lipase-mediated VLDL-TG Hydrolysis* [PDF]

Journal of Biological Chemistry, 2004
ApoAV has been discovered recently as a novel modifier of triglyceride (TG) metabolism, but the pathways involved are currently unknown. To gain insight into the function of apoAV, adenovirus-mediated gene transfer of murine apoa5 to C57Bl/6 mice was ...
F. Schaap, P. Rensen, P. Voshol, Carlos L. J. Vrins, Hendrik N van der Vliet, R. Chamuleau, L. Havekes, A. Groen, K. W. van Dijk   +8 more
semanticscholar   +4 more sources

The very low-density lipoprotein (VLDL) receptor: characterization and functions as a peripheral lipoprotein receptor.

Journal of Atherosclerosis and Thrombosis, 2004
The very low-density lipoprotein (VLDL) receptor is a member of the low-density lipoprotein (LDL) receptor family. In vitro and in vivo studies have shown that VLDL receptor binds triglyceride (TG)-rich lipoproteins but not LDL, and functions as a ...
Sadao Takahashi, J. Sakai, T. Fujino, H. Hattori, Y. Zenimaru, J. Suzuki, I. Miyamori, Tokuo T. Yamamoto   +7 more
semanticscholar   +5 more sources

Adrenal cell aldosterone production is stimulated by very-low-density lipoprotein (VLDL). [PDF]

Endocrinology, 2012
Very low-density lipoproteins (VLDL) are a class of large lipoprotein synthesized in the liver. The key function of VLDL, in vivo, is to carry triglyceride from the liver to adipose tissue.
Yewei Xing, W. Rainey, J. Apolzan, O. Francone, Ruth B. S. Harris, W. Bollag   +5 more
semanticscholar   +4 more sources

Plasma very low density lipoprotein (VLDL) in cholesterol-fed rabbits: chylomicron remnants or liver lipoproteins?

The Journal of Nutrition, 1983
When iodinated hypercholesterolemic plasma very low density lipoprotein (VLDL), chylomicrons or chylomicron remnants were injected intravenously, the apoB of chylomicrons and chylomicron remnants was removed more rapidly than apoB of hypercholesterolemic
Kathryn Haeflein Thompson, D. B. Zilversmit   +1 more
semanticscholar   +3 more sources

VLDL receptor gene therapy for reducing atherogenic lipoproteins

Molecular Metabolism, 2023
Over the past 40 years, there has been considerable research into the management and treatment of atherogenic lipid disorders. Although the majority of treatments and management strategies for cardiovascular disease (CVD) center around targeting low-density lipoprotein cholesterol (LDL-C), there is mounting evidence for the residual CVD risk attributed
Krauss, Ronald M, Lu, Jonathan T, Higgins, Joseph J, Clary, Cathryn M, Tabibiazar, Ray   +4 more
openaire   +5 more sources

Postprandial lipoprotein metabolism: VLDL vs chylomicrons [PDF]

Clinica Chimica Acta, 2011
Since Zilversmit first proposed postprandial lipemia as the most common risk of cardiovascular disease, chylomicrons (CM) and CM remnants have been thought to be the major lipoproteins which are increased in the postprandial hyperlipidemia. However, it has been shown over the last two decades that the major increase in the postprandial lipoproteins ...
Akira Tanaka, Akira Tanaka, Akihiro Inazu, Peter J. Havel, Mitsuyo Okazaki, Takeaki Nagamine, Junji Kobayashi, Yoshiharu Tokita, Masumi Ai, Masumi Ai, Takamitsu Nakano, Katsuyuki Nakajima, Hiroshi Mabuchi, Kimber L. Stanhope   +13 more
openaire   +4 more sources

Heparin binding triggers human VLDL remodeling by circulating lipoprotein lipase: Relevance to VLDL functionality in health and disease

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2022
Hydrolysis of VLDL triacylglycerol (TG) by lipoprotein lipase (LpL) is a major step in energy metabolism and VLDL-to-LDL maturation. Most functional LpL is anchored to the vascular endothelium, yet a small amount circulates on TG-rich lipoproteins. As circulating LpL has low catalytic activity, its role in VLDL remodeling is unclear. We use pre-heparin
Antonio Pérez, José Luis Sánchez-Quesada, Inka Miñambres, Olga Gursky, Shobini Jayaraman   +4 more
openaire   +5 more sources

Down-regulation of lipoprotein lipase and VLDL receptor in rats with focal glomerulosclerosis [PDF]

Kidney International, 2002
Patients and animals with nephrotic syndrome and those with chronic renal failure (CRF) often exhibit hypertriglyceridemia and impaired very low-density lipoprotein (VLDL) clearance. Imai rats that were originally derived from Sprague-Dawley rats develop spontaneous proteinuria, hyperlipidemia, progressive renal insufficiency and histologic changes of ...
Nosratola D. Vaziri, Nosratola D. Vaziri, Kaihui Liang, Kaihui Liang, Tadashi Sato   +4 more
openaire   +3 more sources