Results 31 to 40 of about 285,687 (237)
Cardiovascular Diabetology, 2022 Apolipoprotein C1 (apoC1) is a small size apolipoprotein whose exact role is not totally clarified but which seems to modulate significantly the metabolism of lipoproteins.
Alexia Rouland +5 more
doaj +1 more source
Arteriosclerosis, Thrombosis and Vascular Biology, 1997 Lipoprotein metabolism is regulated by the functional interplay between lipoprotein components and the receptors and enzymes with which they interact.
D. Calvo +3 more
semanticscholar +1 more source
The atherogenic lipoprotein Lp(a) is internalized and degraded in a process mediated by the VLDL receptor. [PDF]
Journal of Clinical Investigation, 1997 Lp(a) is a major inherited risk factor associated with premature heart disease and stroke. The mechanism of Lp(a) atherogenicity has not been elucidated, but likely involves both its ability to influence plasminogen activation as well as its atherogenic potential as a lipoprotein particle after receptor-mediated uptake.
Karen Kozarsky +4 more
openaire +3 more sources
Journal of Clinical Investigation, 2001 LPS-binding protein (LBP) and serum lipoproteins cooperate in reducing the toxic properties of LPS. In the present study, we demonstrate that LBP circulates in association with LDL and VLDL in healthy persons.
Anita C.E. Vreugdenhil +4 more
semanticscholar +1 more source
Very Low Density Lipoprotein (VLDL) Receptor-deficient Mice Have Reduced Lipoprotein Lipase Activity [PDF]
Journal of Biological Chemistry, 2002 Although very low density lipoprotein (VLDL) receptor (VLDLr) knockout mice have been reported to have no lipoprotein abnormalities, they develop less adipose tissue than control mice when fed a high calorie diet. Mice that are deficient in adipose tissue expression of lipoprotein lipase (LpL) also have less fat, but only when crossed with ob/ob mice ...
Sungshin Y. Choi +7 more
openaire +3 more sources
Human CD36 is a high affinity receptor for the native lipoproteins HDL, LDL, and VLDL [PDF]
Journal of Lipid Research, 1998 Mouse and hamster SR-BI glycoproteins and their putative human counterpart CLA-I are so far the only scavenger receptors known to bind both native and modified lipoproteins. CD36, a multigland glycoprotein structurally related to SR-BI and CLA-1, has been reported to bind oxidized low density lipoprotein (OxLDL) and acetylated LDL (AcLDL).
Miguel A. Vega +4 more
openaire +4 more sources
Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2017 Background It is uncertain whether pharmacological reductions in very‐low‐density lipoproteins (VLDLs), and their component triglyceride and cholesterol could reduce residual risk of atherosclerotic cardiovascular disease (ASCVD) events among individuals
P. Lawler +6 more
semanticscholar +1 more source
Autophagy in cancer and protein conformational disorders
FEBS Letters, EarlyView.Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
FEBS Open Bio, EarlyView.In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna +4 more
wiley +1 more source
Diabetes, 2012 Excessive secretion of triglyceride-rich very low-density lipoproteins (VLDL-TG) contributes to diabetic dyslipidemia. Earlier studies have indicated a possible role for the hypothalamus and autonomic nervous system in the regulation of VLDL-TG.
E. Bruinstroop +8 more
semanticscholar +1 more source