Results 11 to 20 of about 449,962 (353)

Triglyceride-rich lipoproteins and their remnants: metabolic insights, role in atherosclerotic cardiovascular disease, and emerging therapeutic strategies—a consensus statement from the European Atherosclerosis Society

European Heart Journal, 2021
Recent advances in human genetics, together with a large body of epidemiologic, preclinical, and clinical trial results, provide strong support for a causal association between triglycerides (TG), TG-rich lipoproteins (TRL), and TRL remnants, and ...
H. Ginsberg, C. Packard, M. Chapman, J. Borén, C. Aguilar-Salinas, M. Averna, B. Ference, D. Gaudet, R. Hegele, S. Kersten, G. Lewis, A. Lichtenstein, P. Moulin, B. Nordestgaard, A. Remaley, B. Staels, E. Stroes, M. Taskinen, L. Tokgözoğlu, A. Tybjaerg-hansen, Jane K. Stock, A. Catapano   +21 more
semanticscholar   +1 more source

The distribution and chemical composition of ultracentrifugally separated lipoproteins in human serum.

Journal of Clinical Investigation, 1955
In the past few years several methods have been developed for the analysis of serum lipoproteins. Lindgren, Elliott, and Gofman (1) have utilized the relatively low density of the lipoproteins to separate them from the other serum proteins by ...
R. Havel, H. Eder, J. H. Bragdon
semanticscholar   +1 more source

Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease.

Journal of Clinical Investigation, 2005
Nonalcoholic fatty liver disease (NAFLD) is characterized by the accumulation of excess liver triacylglycerol (TAG), inflammation, and liver damage.
Kerry L Donnelly, Coleman I. Smith, S. Schwarzenberg, J. Jessurun, M. Boldt, E. Parks   +5 more
semanticscholar   +1 more source

MicroRNAs are Transported in Plasma and Delivered to Recipient Cells by High-Density Lipoproteins

Nature Cell Biology, 2011
Circulating microRNAs (miRNA) are relatively stable in plasma and are a new class of disease biomarkers. Here we present evidence that high-density lipoprotein (HDL) transports endogenous miRNAs and delivers them to recipient cells with functional ...
K. Vickers, Brian T Palmisano, Bassem M. Shoucri, R. Shamburek, A. Remaley   +4 more
semanticscholar   +1 more source

Detailed analysis of the plasma extracellular vesicle proteome after separation from lipoproteins

Cellular and Molecular Life Sciences, 2018
The isolation of extracellular vesicles (EVs) from blood is of great importance to understand the biological role of circulating EVs and to develop EVs as biomarkers of disease.
N. Karimi, Aleksander Cvjetkovic, S. Jang, Rossella Crescitelli, M. H. Hosseinpour Feizi, R. Nieuwland, J. Lötvall, Cecilia Lässer   +7 more
semanticscholar   +1 more source

Effects of aerobic exercise on lipids and lipoproteins

Lipids in Health and Disease, 2017
Dyslipidemia is the risk of cardiovascular disease, and their relationship is clear. Lowering serum cholesterol can reduce the risk of coronary heart disease. At present, the main treatment is taking medicine, however, drug treatment has its limitations.
Ya-ting Wang, Danyan Xu
semanticscholar   +1 more source

Effects of the amount and intensity of exercise on plasma lipoproteins.

New England Journal of Medicine, 2002
BACKGROUND Increased physical activity is related to reduced risk of cardiovascular disease, possibly because it leads to improvement in the lipoprotein profile. However, the amount of exercise training required for optimal benefit is unknown.
W. Kraus, J. Houmard, B. Duscha, K. J. Knetzger, M. Wharton, Jennifer S. McCartney, C. Bales, S. Henes, G. Samsa, J. Otvos, K. Kulkarni, C. Slentz   +11 more
semanticscholar   +1 more source

Comparison of the DASH (Dietary Approaches to Stop Hypertension) diet and a higher-fat DASH diet on blood pressure and lipids and lipoproteins: a randomized controlled trial.

American Journal of Clinical Nutrition, 2016
BACKGROUND The DASH (Dietary Approaches to Stop Hypertension) dietary pattern, which is high in fruit, vegetables, and low-fat dairy foods, significantly lowers blood pressure as well as low-density lipoprotein (LDL) and high-density lipoprotein (HDL ...
S. Chiu, N. Bergeron, Paul T. Williams, G. Bray, B. Sutherland, R. Krauss   +5 more
semanticscholar   +1 more source

Cholesterol determination in high-density lipoproteins separated by three different methods.

Clinical Chemistry, 1977
We describe a simplified method for measuring high-density lipoprotein cholesterol in serum after very-low- and low-density lipoproteins have been precipitated from the specimen with sodium phosphotungstate and Mg2+.
M. Lopes-Virella, P. Stone, S. Ellis, John A. Coiweil   +3 more
semanticscholar   +1 more source

Triglyceride-rich lipoproteins as a causal factor for cardiovascular disease

Vascular Health and Risk Management, 2016
Approximately 25% of US adults are estimated to have hypertriglyceridemia (triglyceride [TG] level ≥150 mg/dL [≥1.7 mmol/L]). Elevated TG levels are associated with increased cardiovascular disease (CVD) risk, and severe hypertriglyceridemia (TG levels ...
P. Toth
semanticscholar   +1 more source