European Heart Journal, 2021 Recent advances in human genetics, together with a large body of epidemiologic, preclinical, and clinical trial results, provide strong support for a causal association between triglycerides (TG), TG-rich lipoproteins (TRL), and TRL remnants, and ...
H. Ginsberg +21 more
semanticscholar +1 more source
JAMA cardiology, 2021 Importance Lipid management typically focuses on levels of low-density lipoprotein cholesterol (LDL-C) and, to a lesser extent, triglycerides (TG). However, animal models and genetic studies suggest that the atherogenic particle subpopulations (LDL and ...
N. Marston +13 more
semanticscholar +1 more source
Relationship between lipoproteins, thrombosis, and atrial fibrillation
Cardiovascular Research, 2021 The prothrombotic state in atrial fibrillation (AF) occurs as a result of multifaceted interactions, known as Virchow’s triad of hypercoagulability, structural abnormalities, and blood stasis.
W. Ding, M. Protty, I. Davies, G. Lip
semanticscholar +1 more source
Lipopolysaccharide (LPS)-binding protein is carried on lipoproteins and acts as a cofactor in the neutralization of LPS. [PDF]
, 1994 Lipoproteins isolated from normal human plasma can bind and neutralize bacterial lipopolysaccharide (LPS) and may represent an important mechanism in host defense against gram-negative septic shock. Recent studies have shown that experimentally elevating
Kane, JP +4 more
core +1 more source
Effects of deletion of the Streptococcus pneumoniae lipoprotein diacylglyceryl transferase gene lgt on ABC transporter function and on growth in vivo [PDF]
, 2012 Lipoproteins are an important class of surface associated proteins that have diverse roles and frequently are involved in the virulence of bacterial pathogens.
A Bidossi +91 more
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MicroRNAs are Transported in Plasma and Delivered to Recipient Cells by High-Density Lipoproteins
Nature Cell Biology, 2011 Circulating microRNAs (miRNA) are relatively stable in plasma and are a new class of disease biomarkers. Here we present evidence that high-density lipoprotein (HDL) transports endogenous miRNAs and delivers them to recipient cells with functional ...
K. Vickers +4 more
semanticscholar +1 more source
Estimating the level of carbamoylated plasma non-high-density lipoproteins using infrared spectroscopy [PDF]
, 2019 Background: The increased cardiovascular morbidity and mortality observed in chronic kidney disease (CKD) patients can be partly explained by the presence of carbamoylated lipoproteins. Lipid profiles can be determined with infrared spectroscopy. In this
De Baene, Linde +5 more
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Data on the effects of low iron diet on serum lipid profile in HCV transgenic mouse model [PDF]
, 2017 Here, we presented new original data on the effects of iron depletion on the circulating lipid pro fi le in B6HCV mice, a murine model of HCV-related dyslipidemia. Male adult B6HCV mice were subjected to non-invasive iron depletion by low iron diet.
Amato, Rosario +3 more
core +2 more sources
Transport of apolipoproteins A-I and A-II by human thoracic duct lymph [PDF]
, 1981 The daily transport of human plasma apolipoproteins A-I and A-II, triglyceride, and total cholesterol from the thoracic duct lymph into plasma was measured in 2 subjects before and 3 subjects after renal transplantation. Lymph triglyceride transport was ~
Anderson, DW +8 more
core +1 more source
Detailed analysis of the plasma extracellular vesicle proteome after separation from lipoproteins
Cellular and Molecular Life Sciences, 2018 The isolation of extracellular vesicles (EVs) from blood is of great importance to understand the biological role of circulating EVs and to develop EVs as biomarkers of disease.
N. Karimi +7 more
semanticscholar +1 more source