Results 201 to 210 of about 572,907 (380)

Assessing Extracellular Vesicle Turnover In Vivo Using Highly Sensitive Phosphatidylserine‐Binding Reagents

Advanced Science, EarlyView.
Extracellular vesicles (EVs) are promising biomarkers, but their heterogeneity limits clinical use. A novel high‐affinity phosphatidylserine (PS)‐binding reagent is introduced that reveals ≈90% of circulating EVs are PS⁺. This enables in vivo tracking, showing rapid EV clearance and retention in spleen immune cells—advancing EV quantification ...
Lavinia Flaskamp, Monica Prechtl, Annkathrin Scheck, Wenbo Hu, Christine Ried, Georg Kislinger, Mikael Simons, Anne B. Krug, Jan Kranich, Thomas Brocker   +9 more
wiley   +1 more source

Hepatic CBP/p300 Orchestrate Amino Acid‐Driven Gluconeogenesis through Histone Crotonylation

Advanced Science, EarlyView.
Hepatic CBP/p300 control amino acid‐driven gluconeogenesis by modulating histone crotonylation. This study identifies 2‐aminoadipate (2‐AAA) as a key metabolite that enhances crotonylation and activates amino acid and gluconeogenic gene expression.
Chunxiang Sheng, Tianjiao Li, Hong Lin, Xiaoqin Ma, Feiye Zhou, Mingzhu Li, Yiru Wang, Shushu Wang, Jialin Tan, Junmin Chen, Yulin Yang, Jianmin Liu, Yufang Bi, Jieli Lu, Xiao Wang, Libin Zhou   +15 more
wiley   +1 more source

"Good" fats, bad news: HDL-delivered vitamin E shields tumors from ferroptosis. [PDF]

Signal Transduct Target Ther
Choi DW, Lee EW.
europepmc   +1 more source

Studies of Fat Lipolysis by Post-Heparin Human Plasma Lipoprotein Lipase and by Human Pancreatic Lipase [PDF]

, 1959
Hyman Engelberg
openalex   +1 more source

Single‐Cell Dissection of the Biological Function and Molecular Features Underlying the Micropeptide LSMEM1 in Kidney

Advanced Science, EarlyView.
LSMEM1, an evolutionarily conserved micropeptide with extreme hydrophobicity (aliphatic index═113) and dynamic amphiphilicity (GRAVY═0.017), features a strong α‐helical transmembrane anchor (residues 64‐86). Single‐cell analysis reveals its critical role in renal lipid homeostasis.
Peimin Liu, Hong Zhang, Shanzhi Yang, Jiaoqing Li, Danfeng Wu, Haosen Xu, Huan Jiang, Yi Jing, Guoxiang Jin, Ruobing Liu, Ning Fan, Xiaoyan Bai   +11 more
wiley   +1 more source

Redefining the essential trafficking pathway for outer membrane lipoproteins

Proceedings of the National Academy of Sciences of the United States of America, 2017
Marcin Grabowicz, T. Silhavy
semanticscholar   +1 more source

Experimental studies on the relationship between the liver function and serum lipoprotein in rabbits

, 1958
Michio Tsunoo
openalex   +2 more sources

Human plasma lipoproteinsIII. The effect of bilateral oophorectomy on the plasma lipoproteins in young women with advanced mammary carcinoma [PDF]

, 1957
Marion Barclay, Richard J. Kaufman, Dorothy W. Sved, Emily D. Kidder, George C. Escher, Mary L. Petermann   +5 more
openalex   +1 more source

A Refined Adaptive Laboratory Evolution Strategy With Biosensor‐Assisted Selection Resolves the Tolerance–Efficiency Trade‐Off in Toxic Chemical Biosynthesis

Advanced Science, EarlyView.
This study presents a refined adaptive laboratory evolution (ALE) strategy to resolve the trade‐off between tolerance and biosynthetic efficiency in toxic chemical production. Combining in vivo mutagenesis, microdroplet‐based evolution, and biosensor‐assisted selection, this strategy rapidly yields robust “win‐win” phenotypes.
Yufei Zhang, Junhua Yun, Guoyan Zhang, Hossain M. Zabed, Yuehui Tian, Xinrui Tang, Jia Li, Xianghui Qi   +7 more
wiley   +1 more source

Quantitative 1H-NMR spectroscopy identifies metabolites and lipoprotein subclasses associated with intermediate phenotypes of chronic diseases in the Japanese Nagahama Study. [PDF]

Sci Rep
Ou H, Kawaguchi S, Brial F, Sonomura K, Kawaguchi T, Gravel AE, Das SK, Auld D, Tabara Y, Jean-Claude BJ, Lathrop M, Matsuda F, Gauguier D.   +12 more
europepmc   +1 more source