Results 261 to 270 of about 319,032 (338)

Low‐Dose X‐Ray Radiation Enhances Intratumoral Accumulation and Antitumor Effects of Nanoscale Coordination Polymers via Neutrophil‐Mediated Trafficking

Advanced NanoBiomed Research, EarlyView.
Low‐dose radiotherapy has been shown to direct nanoscale coordination polymers (NCPs) to tumors by promoting neutrophil recruitment. This immune‐mediated delivery strategy markedly enhances tumor targeting and the therapeutic efficacy of NCPs carrying combination chemotherapies or innate immune modulators, even under clinically relevant radiation ...
Langston Tillman, Xiaomin Jiang, Chaoyu Wang, Yuxuan Xiong, Wenbin Lin   +4 more
wiley   +1 more source

De Novo Design of High‐Affinity Miniprotein Binders Targeting Francisella Tularensis Virulence Factor

Angewandte Chemie, EarlyView.
Hybrid physics and deep‐learning enabled design methods identified miniprotein binders to Flpp3 (Francisella‐like lipoprotein), a key virulence factor from Francisella tularensis. Multiple candidates with nanomolar to picomolar binding affinities were obtained using yeast surface display screening and further experimental optimization.
Gizem Gokce‐Alpkilic, Buwei Huang, Andi Liu, Lieselotte S.M. Kreuk, Yaxi Wang, Victor Adebomi, Yensi Flores Bueso, Asim K. Bera, Alex Kang, Stacey R. Gerben, Stephen Rettie, Dionne K. Vafeados, Nicole Roullier, Inna Goreshnik, Xinting Li, David Baker, Joshua J. Woodward, Joseph D. Mougous, Gaurav Bhardwaj   +18 more
wiley   +2 more sources

Remnant Cholesterol and Cardiovascular Risk in Adults With Type 1 Diabetes: A Nested Case-Control Study. [PDF]

Endocrinol Diabetes Metab
Sebastian-Valles F, Hernando-Alday I, Lander Lobariñas LE, Palacios Berraquero ML, Garai-Hierro J, Roman-Gomez GL, Montes Muñiz Á, Navas-Moreno V, de Martinez Icaya P, Raposo-López JJ, Sampedro-Nuñez MA, González-Ávila C, Arranz-Martín JA, Marazuela M.   +13 more
europepmc   +1 more source

On the structure of human serum high-density lipoprotein: studies by the technique of circular dichroism.

, 1968
A M Scanu, Ronald Hirz
openalex   +1 more source

Metabolism‐Regulating Nanomedicines for Cancer Therapy

Advanced NanoBiomed Research, EarlyView.
This review highlights metabolism‐regulating nanomedicines designed to target glycolytic, lipid, amino acid, and nucleotide pathways in tumors. By incorporating metabolism‐regulating agents into versatile nanocarriers such as liposomes, micelles, dendrimers, and engineered bacteria, these platforms achieve targeted delivery, controlled release ...
Xiao Wu, Shiyi Geng, Jian Yang
wiley   +1 more source

Radiolabeling lipoproteins to study and manage disease. [PDF]

Eur J Nucl Med Mol Imaging
Pérez-Medina C, Fisher EA, Fayad ZA, Mulder WJM, Teunissen AJP.   +4 more
europepmc   +1 more source

Nanobiotechnology‐Based Approaches for Targeted Glioma Therapy

Advanced NanoBiomed Research, EarlyView.
Nanoparticle systems cross the blood–brain barrier to deliver drugs precisely to glioma cells. Lipid, polymeric, and magnetic carriers enable controlled release, tumor targeting, and microenvironment modulation. These nanoplatforms enhance chemotherapy, radiotherapy, and immunotherapy, improving therapeutic efficacy while reducing systemic toxicity ...
Jinwei Li, Yibo He, Yang Zhang, Lining Arnold Ju, Yao Wang, Jianxuan Zhou, Yinying Chai, Xuhui Hui, ShiYuan Tong, Si Zhang, Yanli Tan, Yinyan Wang   +11 more
wiley   +1 more source

Advances in Small Molecule Inhibitors Targeting the Bacterial Lipoprotein Transport System (Lol) in Gram-Negative Bacteria. [PDF]

Chem Asian J
Song S, Shim SY.
europepmc   +1 more source

Atherosclerosis: from lipid-lowering and anti-inflammatory therapies to targeting arterial retention of ApoB-containing lipoproteins. [PDF]

Front Immunol
Araujo G, Valencia LM, Martin-Ozimek A, Soto Y, Proctor SD.   +4 more
europepmc   +1 more source

Studies on the Lipoprotein Lipases of Microorganisms

, 1968
Teiiti Narasaki, Gakuzo Tamura, Κει Arima   +2 more
openalex   +2 more sources