Results 301 to 310 of about 309,210 (382)

Editorial: TRLs (triglycerides-rich lipoproteins): a new target for atherosclerosis. [PDF]

open access: yesFront Endocrinol (Lausanne)
Dong M   +4 more
europepmc   +1 more source

Cutting‐Edge Aptasensing Approaches for Electrochemical Detection of Exosomes Utilizing MXenes

open access: yesChemElectroChem, EarlyView.
This work notably summarizes research on 2D MXenes/MXene's‐hybrid‐based nanoplatforms patterned with aptamers as an alternative to antibodies affording highly sensitive and robust biosensing of exosomes as well as their efficient isolation. The exosomes are highlighted as a valuable source of biomarkers and with the immobilization approaches of ...
Andrej Vikartovský   +5 more
wiley   +1 more source

Harnessing Viral Proteases for Cellular and Molecular Engineering

open access: yesChemistry–Methods, EarlyView.
Engineered viral proteases (VIPs) provide programmable control of protein function with high specificity and low toxicity. Integrated with chemogenetic and optogenetic modules, these VIP systems enable logic gate manipulation for targeted regulation of cell signaling, gene expression, protein secretion, and degradation, thereby offering versatile ...
Mingguang Cui   +2 more
wiley   +1 more source

Model‐Informed Drug Development Applications and Opportunities in mRNA‐LNP Therapeutics

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
The utilization of lipid nanoparticles (LNP) for encapsulating mRNA has revolutionized the field of therapeutics, enabling the rapid development of COVID‐19 vaccines and cancer vaccines. However, the clinical development of mRNA‐LNP therapeutics faces numerous challenges due to their complex mechanisms of action and limited clinical experience.
Jiawei Zhou   +6 more
wiley   +1 more source

Diffuse yellow-golden axillary plaques. [PDF]

open access: yesJAAD Case Rep
Leung AJ   +4 more
europepmc   +1 more source

Photochemistry of Resveratrol: Beyond the Reactivity of Metal‐Free Porphyrins Immobilized on Lignin

open access: yesChemPhotoChem, EarlyView.
Resveratrol photochemistry with singlet oxygen is examined at 450 nm using blue‐LED irradiation and various homogeneous and heterogeneous photosensitizers. Products of CC bond cleavage, electrocyclic ring closure, and [4 + 2] cycloaddition are identified.
Elisa De Marchi   +8 more
wiley   +1 more source

Serum homocysteine is a biomarker for hearing loss associated with or without cardiovascular risk: a cross-sectional study in men. [PDF]

open access: yesEur J Nutr
Morais-Moreno C   +11 more
europepmc   +1 more source

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