Results 31 to 40 of about 14,551 (185)

Kinome profiling of myxoid liposarcoma reveals NF-kappaB-pathway kinase activity and Casein Kinase II inhibition as a potential treatment option

Molecular Cancer, 2010
Background Myxoid liposarcoma is a relatively common malignant soft tissue tumor, characterized by a (12;16) translocation resulting in a FUS-DDIT3 fusion gene playing a pivotal role in its tumorigenesis.
Szuhai Karoly, Bruijn Inge, Schrage Yvonne M, Willems Stefan M, Hogendoorn Pancras CW, Bovée Judith VMG   +5 more
doaj   +1 more source

Axitinib has antiangiogenic and antitumorigenic activity in myxoid liposarcoma [PDF]

, 2016
Myxoid liposarcoma is a rare form of soft-tissue sarcoma. Although most patients initially respond well to treatment, approximately 21% relapse, highlighting the need for alternative treatments.
Kerr, Lauren T., Johns, Terrance G., Kerr, LT, Wilding, AL, Donoghue, JF, Wilding, Alexander L., Donoghue, Jacqueline F., Johns, TG   +7 more
core   +1 more source

The first case of rectal myxoid liposarcoma identified by FUS-DDIT3 fusion, presenting as a submucosal tumor with erosion

Human Pathology: Case Reports, 2018
We experienced a 58-year-old Japanese female complaining of bleedings at defecation for about one year. Endoscopy revealed an Ip submucosal tumor (SMT) at the rectum.
Hiroshi Kono, Yoshitane Tsukamoto, Shohei Matsuo, Hideki Hashidate, Hiroyuki Shibuya, Takashi Kobayashi, Yasumasa Takii, Seiichi Hirota   +7 more
doaj   +1 more source

Clinical features of multiply recurrent retroperitoneal liposarcoma: A single-center experience

Asian Journal of Surgery, 2021
Background: To elucidate the clinicopathological features of multiply recurrent retroperitoneal liposarcoma referred to a tertiary center. Methods: We retrospectively analyzed the clinical data of 40 patients with pathologically proven primary ...
Noriyuki Masaki, Mizuki Onozawa, Takamitsu Inoue, Masahiro Kurobe, Koji Kawai, Jun Miyazaki   +5 more
doaj   +1 more source

FUS-DDIT3 Fusion Oncoprotein Expression Affects JAK-STAT Signaling in Myxoid Liposarcoma

Frontiers in Oncology, 2022
Myxoid liposarcoma is one of the most common sarcoma entities characterized by FET fusion oncogenes. Despite a generally favorable prognosis of myxoid liposarcoma, chemotherapy resistance remains a clinical problem.
Soheila Dolatabadi, Emma Jonasson, Lisa Andersson, Manuel Luna Santamaría, Manuel Luna Santamaría, Malin Lindén, Tobias Österlund, Tobias Österlund, Pierre Åman, Anders Ståhlberg, Anders Ståhlberg, Anders Ståhlberg   +11 more
doaj   +1 more source

Myxoid liposarcoma of bladder

International Journal of Surgery Case Reports, 2021
Abstract Introduction Myxoid liposarcoma of the bladder is a rare mesenchymal tumor which is difficult to diagnose and carries a poor prognosis. The primary treatment is complete surgical resection which is usually followed by adjuvant chemotherapy.
Chudal, Sampanna, Poudyal, Sujeet, Chapagain, Suman, Luitel, Bhoj Raj, Chalise, Pawan Raj, Sharma, Uttam Kumar   +5 more
openaire   +2 more sources

[Myxoid liposarcoma].

Revue medicale de Liege, 2009
Soft-tissue sarcoma is a rare pathology. Due to restricted symptomatology, the diagnosis is often late. Any soft tissues swelling requires at first an ultrasound exam and a radiography, though MRI remains the most appropriate investigation. Treatment will be selected according to the tumor type and its histological grading, these parameters being ...
F, Douchamps, W, Kurth, J M, Crielaard
openaire   +3 more sources

Recurrent massive myxoid liposarcoma in retroperitoneum 10 years post initial operation

IJU Case Reports, 2019
Introduction Myxoid liposarcoma tends to be a relatively good prognosis. Follow‐up is recommended once a year from the 5th year after surgery. Case presentation A 48‐year‐old man had a massive retroperitoneal tumor, measuring approximately 20 cm ...
Takamasa Horiuchi, Shigekatsu Maekawa, Wataru Obara, Haruki Kume, Naoki Matsuoka   +4 more
doaj   +1 more source

Late-onset meningeal metastases in liposarcoma: A case report and review of the literature [PDF]

, 2006
Intracranial metastases from liposarcoma are rare and almost always preceded by the development of systemic tumour spread. We report here a case of liposarcoma with spread to the cranial nervous system 23 years after treatment of the primary tumour.
White, J., Cowie, F., Ferguson, M., Stewart, W.   +3 more
core   +1 more source

Successful resection of a giant thoracic myxoid liposarcoma

, 2018
Primary liposarcoma is an extremely rare disease. We report a case of giant thoracic myxoid liposarcoma that occupied the whole left hemithorax and was successfully resected.
Wei Chieng Pui, Winnie Hui Yee Ling, Sing Yang Soon, Momin Najah   +3 more
core   +1 more source