Results 41 to 50 of about 6,452 (177)

Primary epidural liposarcoma of the cervical spine: Technical case report and review of the literature

Interdisciplinary Neurosurgery, 2015
Liposarcoma is the most common soft tissue sarcoma in adults. These tumors have a high incidence of osseous metastases, with a propensity to the spine; however, primary spinal involvement is very rare.
Hamid Borghei-Razavi, Khairi-Mohamed Daabak, Sahar Bakhti, Uta Schick   +3 more
doaj   +1 more source

Comprehensive genomic profiling of a unique liposarcoma arising in a patient with Li–Fraumeni syndrome and the novel detection of c-myc amplification: a case report

Diagnostic Pathology, 2022
Background Germline TP53 mutations have been frequently reported in patients with Li–Fraumeni syndrome (LFS), resulting in a predisposition to various malignancies.
Hirofumi Watanabe, Fumiyoshi Fujishima, Toru Motoi, Yayoi Aoyama, Tetsuya Niihori, Masanobu Takahashi, Sho Umegaki, Hisashi Oishi, Hiroshi Tada, Ryo Ichinohasama, Hironobu Sasano   +10 more
doaj   +1 more source

Rare Late Cardiac Involvement Following Resected Primary Limb Dedifferentiated Liposarcoma: A Case Report

Clinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT Dedifferentiated liposarcoma (DDLPS) is a rare and aggressive subtype of soft tissue sarcoma, most commonly arising in the extremities or retroperitoneum. Cardiac involvement, whether primary or metastatic, is exceedingly rare and presents significant diagnostic and therapeutic challenges.
Azin Alizadehasl, Saeedeh Baghyari, Mostafa Salimi   +2 more
wiley   +1 more source

Management of myxoid liposarcoma of the extremity.

Oncology letters, 2021
Myxoid liposarcoma (MLPS) is the second most common type of LPS after the well differentiated LPS. MLPS is primarily localized to the extremities. The incidence of LPS is ~2 per million worldwide. MLPS accounts for ~30% of all LPS cases. MLPS is usually encountered in adults, but can also occur in younger individuals more than other types of LPS.
Tfayli, Yehia, Baydoun, Ahmad, Naja, Ahmad Salaheddine, Saghieh, Said   +3 more
openaire   +2 more sources

Psychosocial Impact of Sarcoma: Challenges and Adaptation, a Meta‐Synthesis

Psycho-Oncology, Volume 35, Issue 7, July 2026.
ABSTRACT Objectives Sarcoma is a rare and heterogeneous cancer frequently associated with significant psychosocial burden. This review aims to synthesise qualitative research to examine the psychosocial impact of sarcoma in adults, focusing on how individuals experience and make sense of disruption across diagnosis, treatment, recovery, and ...
R. Beghean, L. O'Driscoll, E. Ryan, P. Carty, F. Larkin, F. O'Keeffe   +5 more
wiley   +1 more source

Primary Orbital Myxoid Liposarcoma

Medical Sciences, 2023
Although liposarcoma is the most prevalent soft tissue sarcoma in adults, head and neck liposarcomas are rare and account for less than 5% of all liposarcomas. The primary orbital location is even more exceptional, with fewer than 100 cases documented in the medical literature.
Benavides-Huerto, Miguel Armando, Paramo-Figueroa, Lourdes, Moreno-Paramo, Daniel, Lagunas-Rangel, Francisco Alejandro   +3 more
openaire   +4 more sources

Advances in Cancer Immunotherapy for Solid Tumors

Advanced Science, Volume 13, Issue 35, 24 June 2026.
Cancer immunotherapy for solid tumors is rapidly evolving beyond classical checkpoint blockade toward more precise strategies. Emerging checkpoint targets, bispecific antibodies, antibody–drug conjugate combinations, personalized vaccines, cellular therapies, and engineered cytokines are expanding therapeutic possibilities, while biomarker‐guided ...
Shira Gabizon‐Peretz, Harriet M. Kluger   +1 more
wiley   +1 more source

Primary Retroperitoneal Myxoid Liposarcomas [PDF]

American Journal of Surgical Pathology, 2016
Myxoid liposarcomas (MLSs) are genetically defined by the presence of DDIT3 gene fusions and most commonly arise in the extremities of young adults. Whether MLSs develop primarily in the retroperitoneum is controversial, and a recent retrospective study found no molecularly confirmed examples.
Setsu, Nokitaka, Miyake, Mototaka, Wakai, Susumu, Nakatani, Fumihiko, Kobayashi, Eisuke, Chuman, Hirokazu, Hiraoka, Nobuyoshi, Kawai, Akira, Yoshida, Akihiko   +8 more
openaire   +2 more sources

Characteristics and Outcomes of Patients With Dedifferentiated Liposarcoma in a US Community Setting

Cancer Medicine, Volume 15, Issue 6, June 2026.
US community oncology patients with dedifferentiated liposarcoma have heterogeneous profiles, treatments, and outcomes. The poor survival rates in this population suggest an unmet need for better therapeutics. ABSTRACT Introduction Clinical characteristics and outcomes of patients treated for dedifferentiated liposarcoma (DDLPS) at community oncology ...
James E. Butrynski, Bal Nepal, Chenxiao Hu, Jinhong Guo, Jennifer Han, Lisa Herms, Alyssa B. Klein, Stephen Stanhope, Elizabeth L. Stanley, Karen Todoroff, Paul Conkling   +10 more
wiley   +1 more source

Concomitant Medication Effects on Immunotherapy Outcomes in Sarcoma: A Pooled Post Hoc Analysis of Seven Phase II Trials

Cancer Medicine, Volume 15, Issue 6, June 2026.
ABSTRACT Background Concomitant medications (CMs) influence outcomes in patients receiving immune checkpoint inhibitors (ICIs), but their impact in sarcoma remains undefined. We assessed the association between CM use and ICI outcomes in patients with advanced or metastatic sarcoma. Methods This pooled analysis included patients from seven investigator‐
Adel Shahnam, Kristen DiConza, Simran Jasnani, Rhoena Desir‐Camille, Evan Rosenbaum, Olayode Babatunde, Ciara M. Kelly, Lauren B. Banks, Viswatej Avutu, Ping Chi, Sujana Movva, Mark A. Dickson, Mrinal M. Gounder, Mary L. Keohan, Robert G. Maki, William D. Tap, Sandra P. D'Angelo   +16 more
wiley   +1 more source