Results 51 to 60 of about 6,452 (177)

What's Your Diagnosis? Large Mediastinal Mass in a Dog

Veterinary Clinical Pathology, EarlyView.
Rosane O. Cruz, Talles M. Almeida, Iris D. S. Menezes, Ludmila R. Moroz, Suane N. Boaventura, Tiago Peixoto, Stella F. Valle, Nicole Hlavac   +7 more
wiley   +1 more source

Pleomorphic Leiomyosarcoma of the Jejunoileal Mesentery: A Histopathological Case Report

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT Gastrointestinal leiomyosarcomas are rare malignancies. Herein, we present a case report of a previously healthy 60‐year‐old female presenting with periumbilical abdominal pain, vomiting, and difficulty in passing stool, with clinical workup, imaging, and surgery defining a small intestine tumor.
George S. Stoyanov, Zlatko Zlatev, Andrea Kirilova, Kristina Naydenova, Hristo Popov   +4 more
wiley   +1 more source

Unveiling the enigma of myxoid liposarcoma: Diagnostic challenges and multidisciplinary triumphs in limb-salvage surgery

Radiology Case Reports
Liposarcoma is a rare soft-tissue sarcoma accounting for about 5% of adult cases; myxoid liposarcoma is the second most common subtype and typically arises in the lower extremities (especially the thigh).
Ikhwan Nasir, MD, Boon Tat Yeap, MD, MMed, Thai Hau Koo, MD, Aaron Gerarde Paul, MD, MMed, Mohd Hazeman Zakaria, MD, MMed   +4 more
doaj   +1 more source

Myxoid liposarcoma. Experience with chemotherapy [PDF]

Cancer, 1994
Myxoid liposarcoma (ML) is the most common type of liposarcoma. It has been classified as an intermediate grade tumor with a definite metastatic potential but a relatively indolent natural history. Little is known about its sensitivity to chemotherapy.The authors reviewed their experience with chemotherapy in ML from 1986 to 1992.
S R, Patel, M A, Burgess, C, Plager, N E, Papadopoulos, K A, Linke, R S, Benjamin   +5 more
openaire   +2 more sources

Neoadjuvant chemotherapy for soft‐tissue sarcoma of the extremities: A post‐hoc Sarculator‐based risk analysis of the EORTC 62961–ESHO 95 randomized trial

Cancer, Volume 132, Issue 9, 1 May 2026.
Abstract Background In the EORTC 62961–ESHO 95 randomized trial (European Organization for Research and Treatment 62961–European Society of Hyperthermia Oncology 95; ClinicalTrials.gov identifier NCT00003052), neoadjuvant chemotherapy (NAC) combined with regional hyperthermia (RHT) improved survival in patients with soft tissue sarcoma (tumor size >5 ...
Markus Albertsmeier, Valeria Milani, Lars H. Lindner, Gabriele Tinè, Sandro Pasquali, Dario Callegaro, Alessandro Gronchi, Hans‐Roland Dürr, Alexander Klein, Dorit Di Gioia, Sultan Abdel‐Rahman, Michael Schmidt, Jens Werner, Michael von Bergwelt‐Baildon, Rosalba Miceli, Rolf Issels   +15 more
wiley   +1 more source

Oncogenic driver and therapeutic target: Prolactin signalling axis in retroperitoneal sarcoma

Clinical and Translational Medicine, Volume 16, Issue 5, May 2026.
Retroperitoneal sarcoma cells can secrete prolactin into the bloodstream, inducing hyperprolactinaemia, which subsequently triggers metabolic reprogramming, such as glucose metabolism. SOX4 can function as a transcription factor that facilitates PRL transcription.
Fu'an Xie, Lingwei Gu, Kunrong Yang, Shuai Wang, Mengmeng Xiao, Guangting Yan, Quan Zhang, Rubing Liang, Aobo Zhuang, Zhe Xi, Yujia Niu, Yanhua Chen, Xiaogang Xia, Linlin Qu, Bin Zhao, Weibing Li, Ting Wu, Chundong Yu, Chenghua Luo, Houzhao Wang, Lanlan Lian, Wengang Li   +21 more
wiley   +1 more source

Decoding the Hexosamine Biosynthesis Pathway: Implications for Novel Therapeutic Strategies in Sarcoma

Journal of Cellular Physiology, Volume 241, Issue 5, May 2026.
ABSTRACT Cancer cells rewire their metabolism to sustain a high proliferation rate. Sensing external cues is essential to match the metabolic fluxes of the cells to the external stimuli. As part of the glucose metabolism, the hexosamine biosynthesis pathway (HBP) is considered a nutrient‐sensing pathway. The HBP produces UDP‐GlcNAc, a key precursor for
Pegah Rahimizadeh, Richard Miallot, Chelsea De Bellis, Philippe Jolivet, Joanna Przybyl   +4 more
wiley   +1 more source

Well‐Differentiated, Low‐Grade Subcutaneous Liposarcoma With a Fatal Outcome in a Dog

Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.
This case report describes a rapidly growing subcutaneous liposarcoma with a fatal outcome in a 10‐year‐old intact male Rottweiler. The neoplasm was suspected cytologically and confirmed histologically. Despite its well‐differentiated, low‐grade features, the dog died within three months of diagnosis, highlighting the potential for metastasis of such ...
Peres Ramos Badial, Thiago André Salvitti De Sá Rocha, Bárbara Ataíde Adorno, Hugo Henrique Ferreira, Didier Quevedo Cagnini   +4 more
wiley   +1 more source

Acral Mesenchymal Spindle Cell Neoplasm With a Novel HMGA2::NCOA2 Fusion

Journal of Cutaneous Pathology, Volume 53, Issue 5, Page 402-406, May 2026.
ABSTRACT Molecular profiling has revolutionized the field of soft tissue pathology, enhancing diagnostic precision and treatment strategies. The integration of molecular analysis and immunohistochemistry has been crucial for classifying diagnostically challenging acral mesenchymal neoplasms.
Grace Z. Armstrong, Carina A. Dehner, Eitan Halper‐Stromberg, Esther Baranov, Anna C. Eden, Rachel P. Kowal   +5 more
wiley   +1 more source

Molecular Characterization and Its Clinical Application of GNAS Variants in Intramuscular Myxoma

Cancer Medicine, Volume 15, Issue 4, April 2026.
This graphical abstract illustrates the workflow of fragment signal analysis for detecting GNAS codon 201 variants, combining PNA clamping PCR, restriction digestion, and capillary electrophoresis to differentiate wild‐type and variant alleles.
Munehisa Kito, Shohei Shigeto, Mai Iwaya, Tomomi Yamaguchi, Masanori Okamoto, Atsushi Tanaka, Akira Takazawa, Hirokazu Ideta, Kaoru Aoki, Hiromasa Hasegawa, Kenji Sano, Tomomi Fujikawa, Tomoki Kosho, Jun Takahashi   +13 more
wiley   +1 more source