Results 61 to 70 of about 40,317 (270)

Molecular pathology of phyllodes tumours of the breast—much more than MED12

Histopathology, EarlyView.
Phyllodes tumours can develop from fibroadenomas bearing MED12 variants by the development of pTERT alterations (“MED12 pathway”) or de novo (“MED12 independent pathway”). Grade progression is associated with increasing genetic complexity including cancer driver gene aberrations. Molecular alterations can be useful in assigning grade and distinguishing
Jia‐Min B Pang, Kylie L Gorringe, Puay Hoon Tan, Stephen B Fox   +3 more
wiley   +1 more source

A metabolic crosstalk between liposarcoma and muscle sustains tumor growth

Nature Communications
Dedifferentiated and Well-differentiated liposarcoma are characterized by a systematic amplification of the Murine Double Minute 2 (MDM2) oncogene.
Gabrielle Manteaux, Alix Amsel, Blanche Riquier-Morcant, Jaime Prieto Romero, Laurie Gayte, Benjamin Fourneaux, Marion Larroque, Nadège Gruel, Chloé Quignot, Gaelle Perot, Solenn Jacq, Madi Y. Cisse, Pascal Pomiès, Coralie Sengenes, Frédéric Chibon, Maud Heuillet, Floriant Bellvert, Sarah Watson, Sebastien Carrere, Nelly Firmin, Romain Riscal, Laetitia K. Linares   +21 more
doaj   +1 more source

Expression of TIM3/VISTA checkpoints and the CD68 macrophage-associated marker correlates with anti-PD1/PDL1 resistance: implications of immunogram heterogeneity. [PDF]

, 2020
Although immunotherapies have achieved remarkable salutary effects among subgroups of advanced cancers, most patients do not respond. We comprehensively evaluated biomarkers associated with the "cancer-immunity cycle" in the pan-cancer setting in order ...
Dressman, Devin, Eskander, Ramez, Glenn, Sean T, Goodman, Aaron, Ikeda, Sadakatsu, Kato, Shumei, Kumaki, Yuichi, Kurzrock, Razelle, Lee, Suzanna, Lenzo, Felicia L, Morrison, Carl, Nikanjam, Mina, Okamura, Ryosuke, Papanicolau-Sengos, Antonios   +13 more
core   +1 more source

Clinicopathologic Analysis of Sarcomas in the Oral and Maxillofacial Region: A Systematic Review

Oral Diseases, EarlyView.
ABSTRACT Objective This study aimed to systematically review primary sarcomas in the oral and maxillofacial region, focusing on patient demographics and sarcoma‐specific characteristics, including clinical presentation, histopathology, treatment approaches, outcomes, and survival rates.
Iara Vieira Ferreira, Reydson Alcides de Lima‐Souza, Talita de Carvalho Kimura, Alfio José Tincani, Marcelo Elias Schempf Cattan, Arthur Antolini‐Tavares, Albina Altemani, Fernanda Viviane Mariano   +7 more
wiley   +1 more source

The first case of rectal myxoid liposarcoma identified by FUS-DDIT3 fusion, presenting as a submucosal tumor with erosion

Human Pathology: Case Reports, 2018
We experienced a 58-year-old Japanese female complaining of bleedings at defecation for about one year. Endoscopy revealed an Ip submucosal tumor (SMT) at the rectum.
Hiroshi Kono, Yoshitane Tsukamoto, Shohei Matsuo, Hideki Hashidate, Hiroyuki Shibuya, Takashi Kobayashi, Yasumasa Takii, Seiichi Hirota   +7 more
doaj   +1 more source

BMP2/BMPR1A is linked to tumour progression in dedifferentiated liposarcomas [PDF]

, 2016
Bone Morphogenic Protein 2 (BMP2) is a multipurpose cytokine, important in the development of bone and cartilage, and with a role in tumour initiation and progression.
Cassidy, A.P., Cassidy, J.W., Harris, O.B., O’Neill, H.L.   +3 more
core   +3 more sources

Survival and prognostic factors among different types of liposarcomas based on SEER database

Scientific Reports
The aim of this study is to elucidate the disparities in survival and risk factors among different subtypes of liposarcoma, through analysis of epidemiological and prognostic data.
Jiaqi Zhao, WenLi Du, XiaoLiang Tao, AiAi Li, Yi Li, Shuai Zhang   +5 more
doaj   +1 more source

Liposarcoma of the glottis: A report of an unusual diagnosis in an unusual location

Radiology Case Reports, 2018
Liposarcoma of the larynx is a rare entity, typically well differentiated with a good prognosis. We present a patient who presented to ENT clinic with a 3-month history of hoarseness.
Amy B. Farkas, MD, Laura K. House, MD, Majid Khan, MD, Ali G. Saad, MD, Ellen Parker, MD, David Joyner, MD   +5 more
doaj   +1 more source

Atypical Lipomatous Tumor of the Tongue:Report of a Case [PDF]

, 2010
The term atypical lipomatous tumor (ALT) is synonymous with well-differentiated liposarcoma (WDL). This tumor occurs very rarely in the tongue. Thus, it is difficult to predict its prognosis. Although recurrence of ALT/WDL is thought to be unlikely after
Iida, Seiji, Ikeya, Yoko, Matsumura, Tatsushi, Mishima, Katsuaki, Mizobuchi, Koichi, Moritani, Norifumi, Wakimoto, Mari, Yamada, Tomohiro   +7 more
core   +1 more source

Long‐term results of palliative placement of very low‐axial force self‐expandable metallic stents for malignant colorectal obstruction

DEN Open, Volume 6, Issue 1, April 2026.
Abstract Objectives Stent placement is a standard option for palliative decompression in patients with malignant colorectal obstruction. Long‐term stent placement is associated with perforation, migration, and stent occlusion. Perforation is associated with life expectancy.
Rika Kyo, Takashi Sasaki, Shuntaro Yoshida, Hiroyuki Isayama, Tomonori Yamada, Toshiyuki Enomoto, Yorinobu Sumida, Toshio Kuwai, Masafumi Tomita, Takeaki Matsuzawa, Rintaro Moroi, Toshiyasu Shiratori, Yoshihisa Saida   +12 more
wiley   +1 more source