Results 11 to 20 of about 114,873 (244)

Chondrotoxicity of Local Anesthetics: Liposomal Bupivacaine Is Less Chondrotoxic than Standard Bupivacaine

Advances in Pharmacological and Pharmaceutical Sciences, 2020
Objective. The purpose of this study is to determine whether (1) liposomal bupivacaine is chondrotoxic; (2) the chondrotoxicity of liposomal bupivacaine differs from standard bupivacaine; and (3) chondrotoxic effects are time dependent.
Travis Farmer, S. Craig Morris, Robert Quigley, Nirav H. Amin, Montri D. Wongworawat, Hasan M. Syed   +5 more
doaj   +2 more sources

The use of liposomal bupivacaine in fracture surgery: a review

Journal of Orthopaedic Surgery and Research, 2023
Historically, opioids have played a major role in the treatment of postoperative pain in orthopedic surgery. A multitude of adverse events have been associated with opioid use and alternative approaches to pain relief are being investigated, with ...
Andrew D. Gailey, Robert F. Ostrum
doaj   +2 more sources

Liposomal bupivacaine reduces opioid requirements following Ravitch repair for pectus excavatum [PDF]

Journal of Anaesthesiology Clinical Pharmacology, 2023
Background and Aims: The management of post-operative pain after surgical repair of pectus excavatum with the Ravitch procedure is challenging. Although previous studies have compared various methods of pain control in these patients, few have compared ...
Rania K Abbasi, Anne E Cossu, Brandon Tanner, Peter Castelluccio, Matthew Hamilton, John Brown, Jeremy Herrmann   +6 more
doaj   +2 more sources

Liposomal Bupivacaine in Implant-Based Breast Reconstruction

Plastic and Reconstructive Surgery, Global Open, 2017
Purpose:. This study evaluates the role of liposomal bupivacaine in implant-based breast reconstruction. Methods:. A prospective, randomized, single-blind trial of liposomal bupivacaine in implant-based breast reconstruction was performed.
Saba Motakef, MD, Wendy W. Wong, MD, Michael J. Ingargiola, MD, David Nguyen, MD, Izabela A. Galdyn, MD, Hahns Y. Kim, MD, Subhas C. Gupta, MD, CM, PhD   +6 more
doaj   +2 more sources

Quality of Recovery After Rotator Cuff Repair With Interscalene Liposomal Bupivacaine Versus Interscalene Nerve Catheter [PDF]

Orthopaedic Journal of Sports Medicine, 2022
Background: Interscalene nerve catheters have been proven to be effective in managing pain after rotator cuff repair (RCR) surgery. Liposomal bupivacaine is a newer approved therapy for use around the interscalene brachial plexus, but its analgesic ...
Jay W. Schoenherr MD, Michael Gonzalez MD, Ricardo Serrano MD, Meredith Park BS, Zachary Lee BA, Kathryn Cobb MD, Christopher Howard MD, David Flynn MD, Quefeng Li PhD, Stuart Grant MD, Ty Bullard MD   +10 more
doaj   +2 more sources

Risk factors for liposomal bupivacaine resistance after total hip or knee arthroplasties: a retrospective observational cohort in 237 patients [PDF]

Patient Safety in Surgery, 2020
Purpose Liposomal bupivacaine demonstrated promise decreasing postoperative pain in total hip and total knee arthroplasty (THA/TKA). Some randomized trials have shown non-superior results; however, confounding variables were not accounted for in such ...
Scott Buzin, Arianna L. Gianakos, Deborah Li, Anthony Viola, Sherif Elkattawy, David M. Keller, Richard S. Yoon, Frank A. Liporace   +7 more
doaj   +3 more sources

Use of Liposomal Bupivacaine in Pediatric Peripheral Nerve Blocks after Traumatic Amputation

Case Reports in Anesthesiology, 2021
Liposomal bupivacaine has been explored for indications in regional anesthesia, but little has been reported about its use in pediatric patients. In March 2021, the FDA approved an indication for liposomal bupivacaine as an infiltrated local anesthetic ...
Gregory M. Halenda, Stylianos Voulgarelis   +1 more
doaj   +2 more sources

Practical Considerations for Liposomal Bupivacaine Use in Orthopaedic Surgery

JBJS Open Access
. » Opioid-related dependence remains a major concern following surgery in the United States, driving increased interest in non-opioid, multimodal pain control strategies within orthopaedic surgery.
Daniel E. Goltz, MD, MBA, Eoghan T. Hurley, MB, MCh, PhD, Jonathan Gustafson, PhD, Paul Sethi, MD, Karl Koenig, MD, Grant Garrigues, MD   +5 more
doaj   +2 more sources

Local anesthetic systemic toxicity with liposomal bupivacaine: a case series and literature review [PDF]

BMC Anesthesiology
Background Local Anesthetic Systemic Toxicity (LAST) is an uncommon complication, with manifestations ranging from mild, non-specific neurological symptoms to severe cardiac arrest. Toxicity specifically associated with liposomal bupivacaine is even more
Liu Zhang, Yanjun Lin, Yan Qiu
doaj   +2 more sources

Periarticular injection of liposomal bupivacaine in total knee arthroplasty

Arthroplasty Today, 2015
The purpose of this study was to determine whether the use of a periarticular injection using liposomal bupivacaine could decrease pain and improve outcomes after total knee arthroplasty.
Bradley T. Webb, MD, J. Reid Spears, BS, Langan S. Smith, BS, Arthur L. Malkani, MD   +3 more
doaj   +3 more sources