Results 41 to 50 of about 2,562 (205)

Multivesicular liposomal bupivacaine at the sciatic nerve [PDF]

Biomaterials, 2014
Clinical translation of sustained release formulations for local anesthetics has been limited by adverse tissue reaction. Exparel™ (DepoFoam bupivacaine) is a new liposomal local anesthetic formulation whose biocompatibility near nerve tissue is not well characterized. Exparel™ injection caused sciatic nerve blockade in rats lasting 240 min compared to
J Brian, McAlvin, Robert F, Padera, Sahadev A, Shankarappa, Gally, Reznor, Albert H, Kwon, Homer H, Chiang, Jason, Yang, Daniel S, Kohane   +7 more
openaire   +2 more sources

Liposomal Bupivacaine Versus Ropivacaine in Combined Thoracic Paravertebral Block and Serratus Anterior Plane Block for Thoracoscopic Surgery: A Randomized Controlled Trial

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT The study aimed to compare the use of liposomal bupivacaine (LB) and ropivacaine hydrochloride (RH) in combined thoracic paravertebral block (TPVB) and serratus anterior plane block (SAPB) during video‐assisted thoracoscopic surgery (VATS).
Lu Jin, Lian Tang
wiley   +1 more source

A prospective analysis describing the innovative use of liposomal bupivacaine in burn patients [PDF]

, 2020
Burn patients frequently require autograft harvesting to facilitate wound healing, often resulting in significant pain. Liposomal bupivacaine is indicated for administration into a surgical site to produce postsurgical analgesia.
Degenkolb, Kerri E., Walroth, Todd A., Blair, Mary E., Hartman, Brett C., Foster, David R., Sood, Rajiv, Boyd, Allison N.   +6 more
core   +1 more source

Epidural analgesia combined with transversus abdominis plane block with liposomal bupivacaine reduces pain after caesarean delivery: a double-blind, randomised controlled trial

Frontiers in Medicine
BackgroundSustained release of bupivacaine can be achieved by encapsulating bupivacaine within multivesicular liposomes, providing localised analgesia for up to 72 h.
Wei Ma, Wei Ma, Yanxi Long, Yanxi Long, Shanshan Ye, Shanshan Ye, Qiang Tao, Qiang Tao, Yang Wang, Yang Wang, Tao Xu, Tao Xu   +11 more
doaj   +1 more source

The role of liposomal bupivacaine in thoracic surgery

Journal of Thoracic Disease, 2019
For advocates of regional analgesia, the appeal of a local anesthetic formulation with a duration of action of several days is clear. Liposomal bupivacaine (LB), now with FDA approval for local infiltration and interscalene nerve block—but not neuraxial use though it has been used there (1), provides multiple days of local anesthetic availability ...
Hassan, Rayaz, E David, Bravos, Allan, Gottschalk   +2 more
openaire   +2 more sources

Clinical practices in the management of cervical Hansen type I intervertebral disc herniation among veterinary neurologists in North America and Europe

Journal of Small Animal Practice, EarlyView.
Objectives To describe current clinical practices in the management of cervical Hansen type I intervertebral disc herniation among American College of Veterinary Internal Medicine/European College of Veterinary Neurology neurologists. Materials and Methods An anonymous web‐based survey was distributed via professional listservs between October and ...
A. Mondino, M. Riobó, N. J. Olby, S. Moore, P. J. Early   +4 more
wiley   +1 more source

Liposomal bupivacaine [PDF]

, 2012
Analjezik etki sürelerini uzatmak, toksisitelerini azaltmak amacıyla lokal anestezikler lipozomlarla enkapsüle edilmektedir. Bu çalışmada multilameller lipozomal bupivakainin farklı formlarını hazırlayarak yapay beyin omurilik sıvısı (BOS) içerisindeki ...
Düzlü, Ayşe
core  

Pharmacokinetics of 2 mg/kg Bupivacaine in a Rectus Abdominis Sheath Block in Horses

Journal of Veterinary Pharmacology and Therapeutics, Volume 49, Issue 4, Page 402-408, July 2026.
ABSTRACT Administering large volumes of bupivacaine in the rectus abdominis sheath (RAS) block in horses could cause local anesthetic toxicity. This study aimed to evaluate the pharmacokinetics of 2 mg/kg bupivacaine in RAS blocks and the associated toxicity risk.
Daniel M. Sakai, Yushun Ishikawa, Jessica S. Y. Im, Shufan Zhang, Rachel A. Reed, Jane E. Quandt, Michele Barletta, Heather K. Knych   +7 more
wiley   +1 more source

Advancing design strategies in smart stimulus‐responsive liposomes for drug release and nanomedicine

BMEMat, Volume 4, Issue 2, June 2026.
Schematic illustration of stimulus‐responsive liposomes designed for controlled drug release and nanomedicine. The innermost circle represents different liposomal structures, including unilamellar, multilamellar, and multivesicular liposomes. The middle layer illustrates the responsive phospholipid components.
Yuchen Guo, Nan Li, Daiwei Zhang, Jingya Gu, Zhihuan Liao, Zihao Teng, Xiangfu Du, Peter S. Timashev, Shipeng Chen, Shuaidong Huo   +9 more
wiley   +1 more source

A dose-response study of epidural liposomal bupivacaine in rabbits [PDF]

, 1999
Liposomes are drug delivery systems used to prolong local effects of bupivacaine. We studied the relationships between motor and hemodynamic changes and epidural doses of plain bupivacaine (P) and liposomal bupivacaine (L) in rabbits equipped with ...
Le Corre, Pascal, Chevanne, François, Legros, Franz Jacques, Leverge, Roger, Malinovsky, Jean-Marc, Pinaud, Michel, Meunier, Jean-François   +6 more
core   +1 more source