Results 61 to 70 of about 2,562 (205)

Liposomal Bupivacaine Does Not Reduce Inpatient Opioid Prescription or Related Complications after Knee Arthroplasty [PDF]

, 2018
Editor’s Perspective What We Already Know about This Topic What This Manuscript Tells Us That Is New
Crispiana Cozowicz, Eric C. Sun, Stavros G. Memtsoudis, Lukas Pichler, Nicole Zubizarreta, Madhu Mazumdar, Jashvant Poeran   +6 more
core   +1 more source

Liquid Crystalline Inverted Lipid Phases and Reverse Micelles in Drug Delivery: From Molecular Design to Therapeutic Potential

Advanced Functional Materials, Volume 36, Issue 32, 20 April 2026.
Liquid crystalline inverted lipid phases and reverse micelles are self‐assembled lipid nanostructures that enhance the solubility, stability, and delivery of diverse therapeutics. This review integrates their physicochemical principles, formulation strategies, drug loading mechanisms, and biomedical applications, highlighting their growing ...
Numan Eczacioglu, Mulazim Hussain Asim, Soheil Haddadzadegan, Andreas Bernkop‐Schnürch   +3 more
wiley   +1 more source

Efficacy of Liposomal Bupivacaine Infiltration on the Management of Total Knee Arthroplasty [PDF]

, 2017
Importance Liposomal bupivacaine is a novel extended-duration anesthetic that has recently been used for local infiltration in total knee arthroplasty (TKA). Athough liposomal bupivacaine is widely used, it is unknown if the benefits justify the cost in
Keiser, Shelly, Freese, Andrew, Sakamoto, Bryan, Meldrum, Russell, Harker, Gene   +4 more
core   +1 more source

Comparison of liposomal bupivacaine and bupivacaine hydrochloride intercostal nerve blocks for postoperative analgesia after thoracic surgery: a multicenter, randomized, three arms trial protocol

Annals of Medicine
Introduction Whether intercostal nerve block can fully realize the prolonged analgesic potential of liposomal bupivacaine remains uncertain. This study aims to evaluate whether liposomal bupivacaine administered via intercostal nerve block confers a long-
Junyi Huang, Lihua Wang, Shiyou Wei, Yuxuan Xin, Rui Chang, Hang Liu, Yiming Yang, Jiong Song, Xin Lv   +8 more
doaj   +1 more source

Smart Wearable Ozone Therapy System for Managing Multidrug‐Resistant Wound Infections

Advanced Therapeutics, Volume 9, Issue 3, March 2026.
A smart wearable ozone therapy system enables precise localized ozone delivery directly to the wound bed through integrated ozone generation, real‐time sensing, and controlled air circulation. Controlled ozone exposure disrupts bacterial membranes, enhances antibiotic accessibility, and supports a clinically translatable strategy for managing multidrug‐
Akshay Krishnakumar, Alexander Roth, Praveen Srinivasan, Muhammad Masud Rana, Nicholas L. F. Gallina, Devendra Sarnaik, Robyn R. McCain, Abigail D. Cox, Mohamed N. Seleem, Arun K. Bhunia, Rahim Rahimi   +10 more
wiley   +1 more source

Local Anesthetics in Cancer: Mechanisms and Translational Perspectives

MedComm – Oncology, Volume 5, Issue 1, March 2026.
Local anesthetics demonstrate multifaceted antitumor effects that collectively contribute to cancer suppression. Beyond canonical sodium channel blockade, these agents exert the following pharmacological actions: inhibition of tumor cell proliferation, suppression of migration and invasion, induction of proapoptotic pathways, attenuation of ...
Wan‐li Wang, Tu Huang, Yi‐hang Hao, Min Zheng, Xin‐hua Liang   +4 more
wiley   +1 more source

Comparison of analgesic and tissue effects of subcutaneous perineural injection of liposomal bupivacaine and bupivacaine hydrochloride in horses with forelimb lameness induced via circumferential clamp [PDF]

, 2020
OBJECTIVE: To evaluate the analgesic and tissue effects of liposomal bupivacaine administered SC as an abaxial sesamoid nerve block in horses with experimentally induced lameness. ANIMALS: 6 healthy mature light-breed horses.
Le, Kayla M., Caston, Stephanie, Hay Kraus, Bonnie, Hossetter, Jesse M.   +3 more
core   +1 more source

The efficacy of liposomal bupivacaine compared with traditional peri-articular injection for pain control following total knee arthroplasty: an updated meta-analysis of randomized controlled trials

BMC Musculoskeletal Disorders, 2019
Background The efficacy of postoperative pain management is an important factor that influences the final outcome of total knee arthroplasty (TKA). Whether liposomal bupivacaine offers better efficacy compared with traditional peri-articular injection ...
Yuan Liu, Yi Zeng, Junfeng Zeng, Mingyang Li, Wenxing Wei, Bin Shen   +5 more
doaj   +1 more source

Wound infiltration with local anesthetics during cesarean delivery with intrathecal opioids: A systematic review and meta‐analysis of randomized control trials

Pregnancy, Volume 2, Issue 2, March 2026.
Abstract Objective To evaluate the effect on maternal pain of local anesthetic wound infiltration for intra‐cesarean delivery analgesia in patients who also received intrathecal opioids Data sources Scopus, PubMed, and Cochrane Central Register of Controlled Trials were searched from the inception of each database to August 2023.
Valentina Frusone, Kavisha Khanuja, Jacqueline Sinnott, Valentina Bellussi, Guillaume Ducarme, Manuel Gomez‐Rios, Jerome Rosetti, Amanda Roman, Vincenzo Berghella   +8 more
wiley   +1 more source

A Novel Use of Liposomal Bupivacaine in Erector Spinae Plane Block for Pediatric Congenital Cardiac Surgery

Case Reports in Anesthesiology, 2021
We describe the use of liposomal bupivacaine (Exparel) in erector spinae plane blocks for two patients undergoing pediatric cardiac surgery with cardiopulmonary bypass and one undergoing division of the compressive vascular ring. The perioperative course
Stylianos Voulgarelis, Gregory M. Halenda, Justinn M. Tanem   +2 more
doaj   +1 more source