Results 61 to 70 of about 3,744 (213)

The efficacy of liposomal bupivacaine compared with traditional peri-articular injection for pain control following total knee arthroplasty: an updated meta-analysis of randomized controlled trials

BMC Musculoskeletal Disorders, 2019
Background The efficacy of postoperative pain management is an important factor that influences the final outcome of total knee arthroplasty (TKA). Whether liposomal bupivacaine offers better efficacy compared with traditional peri-articular injection ...
Yuan Liu, Yi Zeng, Junfeng Zeng, Mingyang Li, Wenxing Wei, Bin Shen   +5 more
doaj   +1 more source

Digital hamartoma resulting in a gait abnormality in a dog

Veterinary Record Case Reports, Volume 14, Issue 1, February 2026.
Abstract A 9‐year‐old Brussels Griffon presented for assessment of a pendulous mass on the dorsal aspect of the third digit of the left hindlimb, following prior trauma to the area during a grooming visit. The primary veterinarian performed a fine needle aspirate of the mass, which revealed a mixed population of inflammatory cells. At presentation, the
Tenley R. Porcher, Laura E. Selmic
wiley   +1 more source

A Novel Use of Liposomal Bupivacaine in Erector Spinae Plane Block for Pediatric Congenital Cardiac Surgery

Case Reports in Anesthesiology, 2021
We describe the use of liposomal bupivacaine (Exparel) in erector spinae plane blocks for two patients undergoing pediatric cardiac surgery with cardiopulmonary bypass and one undergoing division of the compressive vascular ring. The perioperative course
Stylianos Voulgarelis, Gregory M. Halenda, Justinn M. Tanem   +2 more
doaj   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, Volume 36, Issue 1, 2 January 2026.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Noninferiority of Ultrasound‐Guided Modified Intercostal Block to Traditional Approach for Analgesia After Minimally Invasive Repair of Pectus Excavatum in Children: A Randomized Trial

Pain Research and Management, Volume 2026, Issue 1, 2026.
Background For pediatric pectus excavatum, the standard treatment is minimally invasive repair of pectus excavatum (MIRPE). A major challenge, however, is the severe postoperative pain. Although ultrasound‐guided intercostal nerve block (UINB) offers effective analgesia, the technique’s complexity and associated safety concerns are significant barriers,
Ming-Wen Yang, Xian-Lun Duan, Yu-Zhu Cai, Yin Xia, Ying-Ying Sun, Xin-Qi Cheng, Hui Lu   +6 more
wiley   +1 more source

Exparel Versus Bupivacaine: Outcomes, Advantages, And Costs [PDF]

, 2020
Research shows that adequate pain control is associated with increased patient satisfaction, faster rehabilitation, mobilization, reduced hospital stays, and ultimately decreased hospital costs.
Duraney, Jessica
core   +4 more sources

Research Trends in Pain Management After Thoracoscopic Surgery (2015–2024): A Bibliometric Analysis

Pain Research and Management, Volume 2026, Issue 1, 2026.
Background Thoracoscopic surgery, a representative minimally invasive approach in thoracic surgery, is increasingly employed. However, postoperative pain remains a significant barrier to recovery and quality of life. We aimed to quantitatively analyze research on postoperative pain following thoracoscopic surgery over the past decade; to identify the ...
Dezhou Jiang, Funing Liu, Zehao Liu, Jun Peng, Yan Liu, Yan Weng, Run Wang, Qing Zhong, Alessandro Vittori   +8 more
wiley   +1 more source

Study of Peri-Articular Anaesthetic for Replacement of the Knee (SPAARK): study protocol for a patient-blinded, randomised controlled superiority trial of liposomal bupivacaine

Trials, 2019
Background Optimising the management of peri-operative pain and recovery following knee replacement has been identified as a patient priority. Current pain relief strategies use opiate-based analgesia; however, up to 50% of patients experience ...
Ruth Knight, Lisa Poulton, Louise H. Strickland, Thomas W. Hamilton, David Beard, Jonathan Cook, Susan J. Dutton, Jose Leal, Sarah Lamb, Cushla Cooper, Karen L. Barker, David W. Murray, Hemant G. Pandit   +12 more
doaj   +1 more source

Topical versus oral metronidazole for post‐haemorrhoidectomy pain: A systematic review and meta‐analysis of randomized controlled trials

Colorectal Disease, Volume 27, Issue 12, December 2025.
Abstract Background Excisional haemorrhoidectomy is often associated with intense post‐operative pain and delayed recovery. Bacterial colonization may contribute to this discomfort, and metronidazole has been proposed as an analgesic adjunct. This study compared the analgesic efficacy of topical metronidazole with oral metronidazole.
Bernardo Fontel Pompeu, Giulia Luiza Garcia, Gabriel Leal Barone, Isabela Oliveira Rosa, Lucas Soares de Souza Pinto Guedes, Lucas Monteiro Delgado, Claudia Theis, Leonardo de Melo Del Grande, Sergio Mazzola Poli de Figueiredo, Fernanda Bellotti Formiga   +9 more
wiley   +1 more source

Long-term sensorimotor changes after a sciatic nerve block with bupivacaine and liposomal bupivacaine in a high-fat diet/low-dose streptozotocin rodent model of diabetes

Frontiers in Anesthesiology
IntroductionIt is unclear whether patients with diabetes are more susceptible to nerve toxicity of local anesthetics or whether nerve blocks can accelerate the progression of diabetic peripheral neuropathy.
Susanna C. Byram, Susanna C. Byram, Susanna C. Byram, Susanna C. Byram, Krista M. Lotesto, Krista M. Lotesto, Michael Volyanyuk, Michael Volyanyuk, Jacob E. Exline, Jacob E. Exline, Elizabeth A. Sager, Eileen M. Foecking, Eileen M. Foecking, Eileen M. Foecking, Eileen M. Foecking, Eileen M. Foecking   +15 more
doaj   +1 more source