Results 51 to 60 of about 2,540 (202)

Comparison of liposomal bupivacaine and bupivacaine hydrochloride intercostal nerve blocks for postoperative analgesia after thoracic surgery: a multicenter, randomized, three arms trial protocol

Annals of Medicine
Introduction Whether intercostal nerve block can fully realize the prolonged analgesic potential of liposomal bupivacaine remains uncertain. This study aims to evaluate whether liposomal bupivacaine administered via intercostal nerve block confers a long-
Junyi Huang, Lihua Wang, Shiyou Wei, Yuxuan Xin, Rui Chang, Hang Liu, Yiming Yang, Jiong Song, Xin Lv   +8 more
doaj   +1 more source

Wound infiltration with local anesthetics during cesarean delivery with intrathecal opioids: A systematic review and meta‐analysis of randomized control trials

Pregnancy, Volume 2, Issue 2, March 2026.
Abstract Objective To evaluate the effect on maternal pain of local anesthetic wound infiltration for intra‐cesarean delivery analgesia in patients who also received intrathecal opioids Data sources Scopus, PubMed, and Cochrane Central Register of Controlled Trials were searched from the inception of each database to August 2023.
Valentina Frusone, Kavisha Khanuja, Jacqueline Sinnott, Valentina Bellussi, Guillaume Ducarme, Manuel Gomez‐Rios, Jerome Rosetti, Amanda Roman, Vincenzo Berghella   +8 more
wiley   +1 more source

Neurotoxicological assessment after intracisternal injection of liposomal bupivacaine in rabbits

, 1997
Experiments were performed on rabbits randomly assigned to intracisternally receive 0.3 mL of plain bupivacaine 5 mg/mL, liposomal bupivacaine 5 mg/mL, bupivacaine-free liposomes or isotonic phosphate- buffered saline.
Couarraze, Guy, Michel Pinaud, Legros, Franz Jacques, Carine Coussaert, Malinovsky, Jean-Marc, Guy Couarraze, Dan Benhamou, Mokarram Alafandy, Jean-Marie Mussini, Benhamou, Dan, Coussaert, Carine, Mussini, Jean Marie, Pinaud, Michel, Franz J. Legros, Alafandy, Mokarram, Jean-Marc Malinovsky   +15 more
core   +1 more source

A Novel Use of Liposomal Bupivacaine in Erector Spinae Plane Block for Pediatric Congenital Cardiac Surgery

Case Reports in Anesthesiology, 2021
We describe the use of liposomal bupivacaine (Exparel) in erector spinae plane blocks for two patients undergoing pediatric cardiac surgery with cardiopulmonary bypass and one undergoing division of the compressive vascular ring. The perioperative course
Stylianos Voulgarelis, Gregory M. Halenda, Justinn M. Tanem   +2 more
doaj   +1 more source

Digital hamartoma resulting in a gait abnormality in a dog

Veterinary Record Case Reports, Volume 14, Issue 1, February 2026.
Abstract A 9‐year‐old Brussels Griffon presented for assessment of a pendulous mass on the dorsal aspect of the third digit of the left hindlimb, following prior trauma to the area during a grooming visit. The primary veterinarian performed a fine needle aspirate of the mass, which revealed a mixed population of inflammatory cells. At presentation, the
Tenley R. Porcher, Laura E. Selmic
wiley   +1 more source

The efficacy of liposomal bupivacaine compared with traditional peri-articular injection for pain control following total knee arthroplasty: an updated meta-analysis of randomized controlled trials

BMC Musculoskeletal Disorders, 2019
Background The efficacy of postoperative pain management is an important factor that influences the final outcome of total knee arthroplasty (TKA). Whether liposomal bupivacaine offers better efficacy compared with traditional peri-articular injection ...
Yuan Liu, Yi Zeng, Junfeng Zeng, Mingyang Li, Wenxing Wei, Bin Shen   +5 more
doaj   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, Volume 36, Issue 1, 2 January 2026.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Noninferiority of Ultrasound‐Guided Modified Intercostal Block to Traditional Approach for Analgesia After Minimally Invasive Repair of Pectus Excavatum in Children: A Randomized Trial

Pain Research and Management, Volume 2026, Issue 1, 2026.
Background For pediatric pectus excavatum, the standard treatment is minimally invasive repair of pectus excavatum (MIRPE). A major challenge, however, is the severe postoperative pain. Although ultrasound‐guided intercostal nerve block (UINB) offers effective analgesia, the technique’s complexity and associated safety concerns are significant barriers,
Ming-Wen Yang, Xian-Lun Duan, Yu-Zhu Cai, Yin Xia, Ying-Ying Sun, Xin-Qi Cheng, Hui Lu   +6 more
wiley   +1 more source

A liposomal bupivacaine infiltrative block reduces rescue analgesia administration compared to a bupivacaine splash block after canine ovariohysterectomy in a teaching laboratory

, 2023
Objective: This study aimed to determine whether an infiltrative block with liposomal bupivacaine was associated with less rescue analgesia administration and lower pain scores than a bupivacaine splash block after ovariohysterectomy in dogs. Animals:
Paul, April L, Barton, Bruce A, Abelson, Amanda L, Wheeler, Emily P, McCobb, Emily C   +4 more
core   +1 more source

Study of Peri-Articular Anaesthetic for Replacement of the Knee (SPAARK): study protocol for a patient-blinded, randomised controlled superiority trial of liposomal bupivacaine

Trials, 2019
Background Optimising the management of peri-operative pain and recovery following knee replacement has been identified as a patient priority. Current pain relief strategies use opiate-based analgesia; however, up to 50% of patients experience ...
Ruth Knight, Lisa Poulton, Louise H. Strickland, Thomas W. Hamilton, David Beard, Jonathan Cook, Susan J. Dutton, Jose Leal, Sarah Lamb, Cushla Cooper, Karen L. Barker, David W. Murray, Hemant G. Pandit   +12 more
doaj   +1 more source