Results 51 to 60 of about 36,053 (159)

Practical Considerations for Liposomal Bupivacaine Use in Orthopaedic Surgery

JBJS Open Access
. » Opioid-related dependence remains a major concern following surgery in the United States, driving increased interest in non-opioid, multimodal pain control strategies within orthopaedic surgery.
Daniel E. Goltz, MD, MBA, Eoghan T. Hurley, MB, MCh, PhD, Jonathan Gustafson, PhD, Paul Sethi, MD, Karl Koenig, MD, Grant Garrigues, MD   +5 more
doaj   +1 more source

Robot‐assisted resection of diaphragmatic and hepatorenal recess peritoneal endometriosis: Two cases and a narrative review

International Journal of Gynecology &Obstetrics, Volume 173, Issue 2, Page 614-623, May 2026.
Abstract In this report, we describe two cases of diaphragmatic endometriosis with concurrent hepatorenal recess peritoneal involvement managed using robotic‐assisted laparoscopic surgery with the da Vinci Xi platform. In both patients, diaphragmatic implants and hepatorenal recess peritoneal lesions were excised en bloc, followed by resection of ...
Xiaoming Guan, Qiannan Yang, Daniel Y. Lovell, Chunhua Zhang   +3 more
wiley   +1 more source

The efficacy of liposomal bupivacaine compared with traditional peri-articular injection for pain control following total knee arthroplasty: an updated meta-analysis of randomized controlled trials

BMC Musculoskeletal Disorders, 2019
Background The efficacy of postoperative pain management is an important factor that influences the final outcome of total knee arthroplasty (TKA). Whether liposomal bupivacaine offers better efficacy compared with traditional peri-articular injection ...
Yuan Liu, Yi Zeng, Junfeng Zeng, Mingyang Li, Wenxing Wei, Bin Shen   +5 more
doaj   +1 more source

Clinical Retrospective Study on Superior Capsular Reconstruction Using Autologous Fascia Lata Combined With LARS Ligament for Massive Irreparable Rotator Cuff Tears

Orthopaedic Surgery, Volume 18, Issue 5, Page 978-987, May 2026.
For patients with dysfunctional irreparable rotator cuff tears, superior capsular reconstruction using autologous fascia lata combined with LARS artificial ligament effectively restores shoulder function, significantly improves range of motion, and demonstrates a favorable safety profile.
Fangbing Zhu, Weibin Du, Hongfeng Ruan, Meng Ge, Gang Qu, Yanghua Tang, Zhengcong Ye, Shigui Yan   +7 more
wiley   +1 more source

Liquid Crystalline Inverted Lipid Phases and Reverse Micelles in Drug Delivery: From Molecular Design to Therapeutic Potential

Advanced Functional Materials, Volume 36, Issue 32, 20 April 2026.
Liquid crystalline inverted lipid phases and reverse micelles are self‐assembled lipid nanostructures that enhance the solubility, stability, and delivery of diverse therapeutics. This review integrates their physicochemical principles, formulation strategies, drug loading mechanisms, and biomedical applications, highlighting their growing ...
Numan Eczacioglu, Mulazim Hussain Asim, Soheil Haddadzadegan, Andreas Bernkop‐Schnürch   +3 more
wiley   +1 more source

Study of Peri-Articular Anaesthetic for Replacement of the Knee (SPAARK): study protocol for a patient-blinded, randomised controlled superiority trial of liposomal bupivacaine

Trials, 2019
Background Optimising the management of peri-operative pain and recovery following knee replacement has been identified as a patient priority. Current pain relief strategies use opiate-based analgesia; however, up to 50% of patients experience ...
Ruth Knight, Lisa Poulton, Louise H. Strickland, Thomas W. Hamilton, David Beard, Jonathan Cook, Susan J. Dutton, Jose Leal, Sarah Lamb, Cushla Cooper, Karen L. Barker, David W. Murray, Hemant G. Pandit   +12 more
doaj   +1 more source

Smart Wearable Ozone Therapy System for Managing Multidrug‐Resistant Wound Infections

Advanced Therapeutics, Volume 9, Issue 3, March 2026.
A smart wearable ozone therapy system enables precise localized ozone delivery directly to the wound bed through integrated ozone generation, real‐time sensing, and controlled air circulation. Controlled ozone exposure disrupts bacterial membranes, enhances antibiotic accessibility, and supports a clinically translatable strategy for managing multidrug‐
Akshay Krishnakumar, Alexander Roth, Praveen Srinivasan, Muhammad Masud Rana, Nicholas L. F. Gallina, Devendra Sarnaik, Robyn R. McCain, Abigail D. Cox, Mohamed N. Seleem, Arun K. Bhunia, Rahim Rahimi   +10 more
wiley   +1 more source

Long-term sensorimotor changes after a sciatic nerve block with bupivacaine and liposomal bupivacaine in a high-fat diet/low-dose streptozotocin rodent model of diabetes

Frontiers in Anesthesiology
IntroductionIt is unclear whether patients with diabetes are more susceptible to nerve toxicity of local anesthetics or whether nerve blocks can accelerate the progression of diabetic peripheral neuropathy.
Susanna C. Byram, Susanna C. Byram, Susanna C. Byram, Susanna C. Byram, Krista M. Lotesto, Krista M. Lotesto, Michael Volyanyuk, Michael Volyanyuk, Jacob E. Exline, Jacob E. Exline, Elizabeth A. Sager, Eileen M. Foecking, Eileen M. Foecking, Eileen M. Foecking, Eileen M. Foecking, Eileen M. Foecking   +15 more
doaj   +1 more source

Local Anesthetics in Cancer: Mechanisms and Translational Perspectives

MedComm – Oncology, Volume 5, Issue 1, March 2026.
Local anesthetics demonstrate multifaceted antitumor effects that collectively contribute to cancer suppression. Beyond canonical sodium channel blockade, these agents exert the following pharmacological actions: inhibition of tumor cell proliferation, suppression of migration and invasion, induction of proapoptotic pathways, attenuation of ...
Wan‐li Wang, Tu Huang, Yi‐hang Hao, Min Zheng, Xin‐hua Liang   +4 more
wiley   +1 more source

Liposomal bupivacaine

, 2012
Analjezik etki sürelerini uzatmak, toksisitelerini azaltmak amacıyla lokal anestezikler lipozomlarla enkapsüle edilmektedir. Bu çalışmada multilameller lipozomal bupivakainin farklı formlarını hazırlayarak yapay beyin omurilik sıvısı (BOS) içerisindeki ...
Düzlü, Ayşe
core