Results 71 to 80 of about 3,744 (213)

Osmotically balanced, large unilamellar liposomes that enable sustained bupivacaine release for prolonged pain relief in in vivo rat models

Scientific Reports, 2021
To efficiently prolong analgesic effects, we developed osmotically balanced, large unilamellar liposomes (~ 6 μm in diameter) in which highly concentrated bupivacaine (up to 30 mg/mL) was encapsulated, and their sustained bupivacaine release was highly ...
Hyebin Yoo, Jun Seok Park, Seung Soo Oh, Hyun Kang   +3 more
doaj   +1 more source

Innovative Applications of Marine Macroalgae Polysaccharides in Tissue Engineering and Drug Delivery: A Review Study

Health Science Reports, Volume 8, Issue 11, November 2025.
ABSTRACT Background and Aims Marine macroalgae are abundant sources of bioactive polysaccharides—including alginate, fucoidan, ulvan, carrageenan, and agarose—widely recognized for extensive biomedical applications. These polysaccharides exhibit remarkable biological properties, such as immunostimulatory, anticancer, antioxidant, antimicrobial, and ...
Foroozan Jalalibidgoli, Pardis Irankhahi, Helia Hajihassani, Ali Akbar Ghotbi‐Ravandi   +3 more
wiley   +1 more source

Confronting the opioid crisis: Practical pain management and strategies: AOA 2018 critical issues symposium [PDF]

, 2019
The United States is in the midst of an opioid crisis. Clinicians have been part of the problem because of overprescribing of narcotics for perioperative pain management.
Hsu, Joseph R, Jahangir, A Alex, Miller, Anna N, Mir, Hassan R, Obremskey, William T   +4 more
core   +1 more source

Isolated pores dissected from human two-pore channel 2 are functional [PDF]

Multi-domain voltage-gated ion channels appear to have evolved through sequential rounds of intragenic duplication from a primordial one-domain precursor. Whereas modularity within one-domain symmetrical channels is established, little is known about the
Miles, A.J., Patel, S., Penny, C.J., Rahman, T., Sula, A., Wallace, Bonnie A.   +5 more
core   +1 more source

Liposomal bupivacaine peripheral nerve block for the management of postoperative pain [PDF]

, 2016
Background Postoperative pain remains a significant issue with poor perioperative pain management associated with an increased risk of morbidity and mortality.
Athanassoglou, Vassilis, Hamilton, Thomas, Mellon, Stephen, Murray, David, Pandit, Hemant G., Strickland, Louise H., Trivella, Marialena   +6 more
core   +2 more sources

PI3K/AKT/mTOR Axis in Cancer: From Pathogenesis to Treatment

MedComm, Volume 6, Issue 8, August 2025.
The PI3K/AKT/mTOR signaling axis is crucial in cancer progression, regulating cell growth, survival, and metabolism. Often hyperactivated through mutations or loss of tumor suppressors such as PTEN, this pathway promotes cancer cell proliferation and survival by inhibiting apoptosis and activating mTOR, which drives protein synthesis and suppresses ...
Mingyang Jiang, Ke Zhang, Zhenwang Zhang, Xinran Zeng, Zihang Huang, Peizhuo Qin, Zhilin Xie, Xue Cai, Milad Ashrafizadeh, Yu Tian, Ruqiong Wei   +10 more
wiley   +1 more source

Transversus abdominis plane block with liposomal bupivacaine versus standard bupivacaine for postoperative analgesia in elective cesarean section: a systematic review and meta-analysis

Frontiers in Anesthesiology
BackgroundTransversus abdominis plane (TAP) block with bupivacaine is commonly used for analgesia after cesarean deliveries. Liposomal bupivacaine has been incorporated into TAP blocks to potentially prolong analgesic effects and reduce opioid use ...
Matheus Requena Escobar, Sara Amaral, Letícia Oku, Vitor Felippe, Carlos Darcy Bersot, Thomas Rolf Erdmann   +5 more
doaj   +1 more source

اثر بلوک پری‌آنال با بوپيواکائين بر درد پس از هموروئيدکتومی [PDF]

, 2013
زمينه و هدف: يکی از شايع‌ترين اعمال جراحی، هموروئيدکتومی است و چون ناحيه آناتوميک کانال آنال (محل عمل)، توسط اعصاب متعددی عصب‌دهی می‌شود، درد از مشکلات شايعی است که بيماران بعد از اين عمل جراحی، با آن مواجه می‌باشند.
بی آزار, گلاره, حقيقی, محمد, صدیقی نژاد, عباس, علیزاده, مهدی, نادری نبی, بهرام, کرد, علیرضا, کرمی, محمدصدیق   +6 more
core  

Liposomal Bupivacaine [PDF]

Anesthesiology, 2020
openaire   +2 more sources

Onset and duration of liposomal bupivacaine in Holstein calves using a cornual nerve block [PDF]

, 2020
Dairy calves are routinely disbudded during their first few weeks of life in order to prevent injuries and provide safety for their handlers. Disbudding is a procedure that removes the calves’ horn buds and activates nociceptors and causes acute pain and
Gomez, Selena
core   +2 more sources