Results 171 to 180 of about 129,053 (299)

Lyophilized Synthetic Platelets: In Vitro Characterization and in Vivo Evaluation in Mouse Thrombocytopenia Model

Advanced Science, EarlyView.
ABSTRACT Platelet transfusions to treat bleeding complications use donor‐derived platelets stored at room‐temperature, that have a shelf‐life of only 5–7 days due to bacterial contamination risks. Cold‐stored and freeze‐dried platelets are being investigated for extending shelf‐life, but these still have the inherent challenge of donor‐dependency.
Ujjal Didar Singh Sekhon, Dante Disharoon, Shrijal S. Desai, Baylee Traylor, Emily Gahagan, Emma Quill, Kristin Aldridge, Norman F. Luc, Sonali Rohiwal, Shruti Raghunathan, Rebecca Ahn, Sana Syed, Alexander Dornback, Bipin Chakravarthy Paruchuri, Andrew Ditto, Susan M. Shea, Philip C. Spinella, Matthew D. Neal, Michael A. Bruckman, Christa L. Pawlowski, Anirban Sen Gupta   +20 more
wiley   +1 more source

ROS-sensitive liposomal co-delivery of photosensitizer, factor Xa inhibitor, and PD-L1 blockade enhances photodynamic immunotherapy. [PDF]

Theranostics
Mai Y, Chen Y, Li C, Wang T, Ding S, Zhang H, Lin H, Jiang L, Yuan C, Zhou X, Huang M, Xu P.   +11 more
europepmc   +1 more source

Tumor‐Induced Splenic Remodeling: Mechanisms of Systemic Immunosuppression and Emerging Therapeutic Opportunities

Advanced Science, EarlyView.
ABSTRACT Despite the transformative impact of cancer immunotherapies such as immune checkpoint blockade, durable clinical responses remain limited. Increasing evidence indicates that antitumor immunity is governed not only by the tumor microenvironment, but also by systemic immune regulation mediated by peripheral immune organs. Among these, the spleen
Yuehua Liu, Xiaoqian Nie, Xiaofei Gao
wiley   +1 more source

Osteopontin from monocyte-derived dendritic cells mediates ozone-induced pulmonary responses in mice. [PDF]

Front Immunol
Tashiro H, Kuwahara Y, Kurihara Y, Konomi Y, Takamori A, Kimura S, Takahashi K.   +6 more
europepmc   +1 more source

Enzyme‐Activated MRI for In Vivo Glucose Imaging via a Biodegradable Chromium Nanoprobe

Advanced Science, EarlyView.
Enzyme‐activated MRI (eaMRI) using a biodegradable CrGOx@Lip nanoprobe enables glucose‐specific imaging in vivo. GOx catalyzes glucose oxidation, triggering in situ formation of paramagnetic chromium gluconate and amplifying T1. This radiation‐free strategy maps tumor glucose uptake via the Warburg‐effect, quantifies hepatic glucose accumulation in ...
Yan Xu, Weitao Yang, Yanjing Yun, Hui Wang, Zhuoyao Wu, Youyi Yu, Bingbo Zhang   +6 more
wiley   +1 more source

cDC1 Subtype-Specific In Vivo Targeting of Liposomes. [PDF]

Adv Sci (Weinh)
Schaaf M, Fichter M, Jian L, Schön F, Jung C, Schneider P, Speth K, Mateos-Maroto A, Mailänder V, Koynov K, Morsbach S, Landfester K.   +11 more
europepmc   +1 more source

Effects of Liposome Composition and Size on Protein Corona Formation: Competitive Replacement of Abundant Proteins by High-Affinity Proteins on the Liposome Surface. [PDF]

Adv Healthc Mater
Lee H.
europepmc   +1 more source

Multidimensional and Multifunctional Laser‐Induced Graphene (LIG) for Point‐of‐Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine

Advanced Science, EarlyView.
Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang, Yurou Yuan, Xiaohong Ding, Wing Cheung Mak   +3 more
wiley   +1 more source

Modular noncovalent functionalization of electrospun piezoelectric scaffolds with bioactive nanocarriers.

Biomater Sci
Bortel SP, Chowdhury SSJ, Cheng J, Uvaldo D, Wright M, Kylat AM, Arinzeh TL, Correa S.   +7 more
europepmc   +1 more source

Surface-engineered dual drug-loaded tumor-targeted liposomal nanoparticles to overcome the therapeutic resistance in glioblastoma multiforme. [PDF]

Commun Med (Lond)
Angom RS, Rachamala HK, Nakka NMR, Madamsetty VS, Suarez-Meade P, Fernandez-Gil BI, Kulkarni T, Weil RM, Dutta S, Wang E, Bhattacharya S, Pal K, Quinones-Hinojosa A, Mukhopadhyay D.   +13 more
europepmc   +1 more source