Aberrant Mitochondrial Metabolism in Alzheimer's Disease Links Energy Stress with Ferroptosis
Alves et al. reveal how energy loss and oxidative stress, two major features of Alzheimer's disease, are connected. Mitochondria controls the flux of the antioxidant glutathione (GSH), via facilitating both its production and consumption. Energy restriction limits GSH synthesis, conferring vulnerability to cell death by ferroptosis, implicated as a ...
Francesca Alves+17 more
wiley +1 more source
Intrapleural injection of bupivacaine liposome for pain management after thoracoscopic surgery. [PDF]
Qin J, Lei Z, Li R, Zhou Y, Zhong Y.
europepmc +1 more source
Safety and Side Effect Profile of Liposome Bupivacaine (Exparel) in Peripheral Nerve Blocks
B. Ilfeld+6 more
semanticscholar +1 more source
Supramolecular Lubricating Hydrogel Microspheres Reshape Damaged Matrix Regeneration
The supramolecular lubricating hydrogel microspheres can provide stable mechanophysical protection at damaged matrix through interfacial hydration lubrication: in the early and middle stages, microspheres can actively provide microscale supramolecular lubrication (µ ≈ 0.04) for damaged matrix; in the late stage, the wear debris induced by shear and ...
Hui Yuan+3 more
wiley +1 more source
Self-assembled Ac-FFA-NH<sub>2</sub> based hydrogels with strong immunostimulating activity for vaccine delivery. [PDF]
Serdar NG+6 more
europepmc +1 more source
Hepatic uptake and degradation of unilamellar sphingomyelin/cholesterol liposomes: a kinetic study.
Karl J. Hwang+2 more
openalex +1 more source
Theranostic Toolbox for Neutrophil Functionalization
Here, neutrophil‐specific fluorine nanoparticles additionally equipped with either activating or inhibiting peptides for a background‐free 19F MRI‐based nanotheranostic approach are engineered. It is demonstrated that this approach is suitable to visualize and concomitantly direct neutrophil functionality depending on the specific requirements to ...
Pascal Bouvain+11 more
wiley +1 more source
A homogeneous immunoassay technology based on liposomes and the complement system enables one-step, no-wash, rapid diagnostics directly in serum. [PDF]
Hoecherl K+13 more
europepmc +1 more source
Selective killing of T lymphocytes by phototoxic liposomes.
Shrishailam Yemul+5 more
openalex +1 more source
Large‐Scale Production of Transfusion‐Ready Red Blood Cells From Induced Pluripotent Stem Cells
A scalable, dynamic culture system is developed to produce red blood cells from induced pluripotent stem cells. It achieves high yields with up to 70% enucleation, not previously shown in dynamic systems, overcoming key limitations and enabling large‐scale production.
Eszter Varga+13 more
wiley +1 more source