Molecular Dynamics Simulations and Empirical Observations on Soy Lecithin Liposome Preparation
Indonesian Journal of Chemistry, 2016 Soy lecithin is a phospholipid often used in liposome formulations. Determination of water and phospholipid composition is one of the problems in the liposome formulation.
Rini Dwiastuti +4 more
doaj +1 more source
Curcumin-Loaded Liposome Preparation in Ultrasound Environment under Pressurized Carbon Dioxide
Foods, 2022 Curcumin-loaded liposomes were prepared using a supercritical carbon dioxide (SCCO2)–ultrasound environment system. The experiments were performed at temperatures of 40–70 °C and pressures of 10–25 MPa in a batch system with ultrasonication for 60 min ...
Wahyudiono +7 more
doaj +1 more source
Native silica nanoparticles are powerful membrane disruptors [PDF]
, 2015 Silica nanoparticles are under development for intracellular drug delivery applications but can also have cytotoxic effects including cell membrane damage.
Alkhammash, Hend I. +3 more
core +1 more source
Simulation of pulsatory liposome working using a linear approximation for transmembrane pore dynamics [PDF]
INCAS BulletinThis paper presents an analytical solution of the differential equations describing the pulsatory liposome dynamics. We consider a unilamellar liposome filled with an aqueous solution of osmotic solute inserted in a hypotonic aqueous medium.
Dumitru POPESCU +2 more
doaj +1 more source
Liposome Deformation Induced by Membrane-Binding Peptides
Micromachines, 2023 This paper presents an investigation of liposome deformation and shape distortion using four membrane-binding peptides: TAT and C105Y as cell-penetrating peptides (CPPs), and melittin and ovispirin as antimicrobial peptides (AMPs).
Kayano Izumi +2 more
doaj +1 more source
Biochemistry and Biophysics Reports, 2016 Exhaustive exercise promotes muscle injury, including myofiber lesions; however, its exact mechanism has not yet been elucidated. In this study, we tested the hypothesis that macrophage depletion by pretreatment with clodronate liposomes alters muscle ...
Noriaki Kawanishi +4 more
doaj +1 more source
Bioscience Reports, 2002 The clearance rate of liposomal drugs from the circulation is determined by the rate and extent of both drug release and uptake of liposomes by cells of the mononuclear phagocyte system (MPS). Intravenously injected liposomes initially come into contact with serum proteins.
Tatsuhiro, Ishida +2 more
openaire +2 more sources
OPA1 disease alleles causing dominant optic atrophy have defects in cardiolipin-stimulated GTP hydrolysis and membrane tubulation [PDF]
, 2010 The dynamin-related GTPase OPA1 is mutated in autosomal dominant optic atrophy (DOA) (Kjer type), an inherited neuropathy of the retinal ganglion cells.
Alexander +28 more
core +3 more sources
Calli Essential Oils Synergize with Lawsone against Multidrug Resistant Pathogens. [PDF]
, 2017 The fast development of multi-drug resistant (MDR) organisms increasingly threatens global health and well-being. Plant natural products have been known for centuries as alternative medicines that can possess pharmacological characteristics, including ...
Alsaadi, Abrar I +6 more
core +2 more sources
Liposomal delivery of hydrophobic RAMBAs provides good bioavailability and significant enhancement of retinoic acid signalling in neuroblastoma tumour cells [PDF]
, 2020 Retinoid treatment is employed during residual disease treatment in neuroblastoma, where the aim is to induce neural differentiation or death in tumour cells.
Bilip, Maja +11 more
core +4 more sources