Results 171 to 180 of about 147,676 (314)

Wireless Bioelectronic Modulation of Membrane Potential in Glioblastoma Using Carbon Nanotube Porins

Advanced Science, EarlyView.
A schematic illustrating glioblastoma cell membrane modulation using carbon nanotube porins (CNTPs) and an applied voltage. CNTPs enable ion flux leading to changes in membrane potential. This figure summarizes the concept of bioelectronic control of cell membrane voltage.
Fleur Groualle, David Onion, Julie A. Watts, Graham A. Rance, Aleksandr Noy, Beth Coyle, Frankie J. Rawson   +6 more
wiley   +1 more source

Biomimetic liposomes in drug delivery: from design mechanisms to applications.

Chem Soc Rev
Li Z, Li M, Lu J.
europepmc   +1 more source

Targeted nanoparticles for placenta-specific drug delivery in pregnant rhesus macaques. [PDF]

Theranostics
Schmidt JK, Mitzey AM, Keding LT, Shaw SA, Renshall L, Beards F, Al-Mugotir MH, Simmons HA, Basu P, Schotzko ML, Ren E, Golos TG, Harris LK.   +12 more
europepmc   +1 more source

A low-molecular-weight heparin-coated doxorubicin-liposome for the prevention of melanoma metastasis

, 2015
Yi Chen, Na Lu, Jianqing Peng, Miaomiao Han, Omar Mezghrani, Danrong Hu, Xue Ke   +6 more
openalex   +1 more source

USP35 Acts as a Deubiquitinating Enzyme for ID3 to Promote Immune Escape in Colorectal Cancer

Advanced Science, EarlyView.
USP35 stabilizes ID3 expression by deubiquitinating the K2/K30 site, thereby upregulating PD‐L1 and promoting immune escape in colorectal cancer. IU1, an inhibitor of USP35 enzyme activity, has been shown to inhibit USP35, thereby accelerating ID3 degradation, enhancing CD8+ T cell killing, and reversing the immunosuppressive microenvironment ...
Wenxin Chen, Ling Wang, Hongmei Fan, Lisheng Li, Lingyu Zhang, Ruoxin Li, Fang Liu, Fuli Wen, Yunbin Ye, Chuanzhong Huang   +9 more
wiley   +1 more source

Development and in vitro evaluation of liposomes and immunoliposomes containing 5-fluorouracil and R-phycoerythrin as a potential phototheranostic system for colorectal cancer. [PDF]

Beilstein J Nanotechnol
Rodrigues Camelo R, Vandesmet VCS, Vital Baccallini O, de Brito Vieira Neto J, Moreira TDS, Almeida Moreira Leal LK, Pessoa C, Cerri DG, Bentley MVLB, Eloy JO, Júnior IJDS, Petrilli R.   +11 more
europepmc   +1 more source

Targeted Extracellular Vesicles Deliver Asiaticoside to Inhibit AURKB/DRP1‐Mediated Mitochondrial Fission and Attenuate Hypertrophic Scar Formation

Advanced Science, EarlyView.
Hypertrophic scar formation is driven by excessive mitochondrial fission in wound macrophages, which we discover is governed by a novel AURKB‐DRP1(Ser616) axis. The study develops a targeted therapy using cRGD‐decorated extracellular vesicles to deliver the natural compound Asiaticoside specifically to macrophages.
Luyu Li, Chenli Si, Xue Wang, Xiaojin Wu, Ying Shang, Shengfang Ge, Yong Wang, Yong Zuo, Zhen Zhang   +8 more
wiley   +1 more source

Photocatalytic Biohybrid Vesicles. [PDF]

Chem Rev
Butt JN, Jeuken LJC.
europepmc   +1 more source

Resveratrol liposomes and lipid nanocarriers: Comparison of characteristics and inducing browning of white adipocytes

, 2017
Yujiao Zu, Haley Overby, Guofeng Ren, Zhaoyang Fan, Ling Zhao, Shu Wang   +5 more
openalex   +2 more sources

A Simplified Three‐Tailed N‐Alkyl Phosphoramidate Lipid Platform Enables Inguinal Adipose‐Accumulated mRNA Delivery for Anti‐Obesity Therapy

Advanced Science, EarlyView.
This study develops an mRNA therapy encoding a long‐acting GLP‐1/FGF21 fusion protein. A three‐tailed ionizable lipid engineered three‐component lipid nanoparticle delivers the mRNA to inguinal adipose tissue. In obese mice, this targeted, dual‐hormone treatment potently reduces body weight, fat mass, presenting a localized strategy for metabolic ...
Bin Ma, Yunxuan Liu, Huijuan Zhang, Yian Fang, Yizhe Xue, Junsheng Xue, Ziqiong Jiang, Tianyan Zhou, Yanyun Hao, Fei Xie, Lei Miao   +10 more
wiley   +1 more source