Results 231 to 240 of about 147,676 (314)

Transferrin-Functionalized Liposomes Enhance MAPT-ASO Transport Across a 3D Blood-Brain Barrier Microvascular Network Model. [PDF]

Int J Mol Sci
Konig S, Shen X, Mantovani G, Winkler GS, Zhu Z, Moeendarbary E.   +5 more
europepmc   +1 more source

Engineered CAR‐NKT Extracellular Vesicles Suppress Tumor Progression and Enhance Antitumor Immunity

Advanced Science, EarlyView.
TM4SF1‐nanobody engineered CAR‐natural killer T–derived extracellular vesicles (CARTM4SF1‐EVs) provide a cell‐free alternative to CAR‐NKT therapy, achieving potent, targeted antitumor activity with reduced toxicity. CARTM4SF1‐EVs induce immunogenic cell death, remodel the tumor microenvironment, and enhance CD8⁺ T‐cell antitumor immunity.
Xiaopei Hao, Chengming Qu, Yanzhao Zhou, Xiaoqian Wang, Xiangjun Qian, Xun Chen, Feng Han, Xiaokai Zhang, Yiyi Ji, Han Li, ChengWei Ju, Peng Xia, Weiwei Tang, Hao Zhuang, Jinxue Zhou   +14 more
wiley   +1 more source

Study on Dual-Targeted Liposomes Containing Curcumin-Copper Chelate in the Treatment of Triple-Negative Breast Cancer. [PDF]

Pharmaceuticals (Basel)
Wu L, Guo X, Guo P.
europepmc   +1 more source

CXC Chemokine‐Driven Vascular Reprogramming: Modulating Tumor Vasculature to Boost Therapeutic Response

Advanced Science, EarlyView.
Tumor vascular remodeling is discussed from a chemokine‐centered perspective. This review summarizes the bidirectional, temporal, and tissue‐specific roles of CXC chemokines in regulating vascular function and immune accessibility. A functional vascular normalization score is introduced as a conceptual framework to integrate dynamic vascular and immune
Hongdan Chen, Yinde Huang, Juntong Wu, Ziying Yi, Yao Li, Zeyu Yang, Fan Zhang, Chong Li   +7 more
wiley   +1 more source

An ultrasensitive and modular platform to detect Siglec ligands and control immune cell function. [PDF]

Sci Adv
Jame-Chenarboo Z, Schmidt EN, Crichton M, Takahashi-Yamashiro K, Lima GM, Luna-Dulcey L, Jung J, Ivison S, St Laurent CD, Enterina JR, Lin SY, Sarkar S, Joe M, Mozaneh F, John R, Nanjappa SG, Malaker SA, Levings MK, Marth JD, Derda R, Macauley MS.   +20 more
europepmc   +1 more source

Quantification of Single‐Cell Cysteine Using an Electrochemical Nanosensor for Predicting Tumor Disulfidptosis Susceptibility

Advanced Science, EarlyView.
Cysteine attracts interest due to its unique electrochemical activity and emerging relationship with disulfidptosis. This study develops a new electrochemical nanosensor, which represents the first of its kind capable of detecting intracellular cysteine for various types of tumor cells and primary tumor cells in mice to evaluate disulfidptosis ...
Congcong Zhang, Xiangdi Zhang, Shushen Li, Yuyang Li, Bei Yuan, Mingshuang Zheng, Shuo Zhang, Fangping Yuan, Min Jia, Lixia Lu, Jun Zhou, Zhenguo Zhang, Xin Du   +12 more
wiley   +1 more source

Structure-Based Prediction of Molecular Interactions for Stabilizing Volatile Drugs. [PDF]

Pharmaceutics
Zhao Y, Bai D, Yang B, Wu T, Wu G, Ye T, Wang S.   +6 more
europepmc   +1 more source

Organic Afterglow Vesicles

Advanced Science, EarlyView.
This work constructs organic afterglow vesicles through polymerization‐induced self‐assembly (PISA), integrating thermally activated delayed fluorescence (TADF) type organic afterglow emitters into block copolymer nanostructures. The resulting vesicles exhibited significant room‐temperature afterglow, with an emission lifetime exceeding 200 ...
Siqi Zhu, Biao Xu, Ting Luo, Hui Li, Xinyi Wu, Siqi Zheng, Haodong Li, Yong Gao, Kaka Zhang   +8 more
wiley   +1 more source

Liposomal co-delivery of β-carotene and doxorubicin for enhanced colorectal-cancer therapy. [PDF]

Sci Rep
Alhazzaa DM, Shafaa MW, Elabed S, Shafaa AM, Omran MM.   +4 more
europepmc   +1 more source