Results 71 to 80 of about 169,489 (307)

Research progress of targeted liposomes

, 2020
With the deep research on liposomes,research on targeted liposomes has also made great progress.Targeting liposomes is an ideal pharmaceutical carrier with the advantages of high targeting,low toxicity and long-term sustained release.In recent years ...
李文军, 杨贵兰, 王春华
core   +1 more source

Prostate Cancer Patient‐Derived Organoids (PDOs) as Functional Avatars for Antisense Oligonucleotide (ASO)‐Based Personalized Therapy

Advanced Healthcare Materials, EarlyView.
Prostate patient‐derived organoids (PDOs) were established from TURP and biopsy specimens with >90% success and retain key features of their tissues of origin, making them functional avatars for antisense oligonucleotide (ASO) therapy . Transfecting single cells outside the Matrigel matrix and then reconstituting organoids overcomes the 3D delivery ...
Thi Thom Tran, Thi Tu Uyen Phan, Michael Baboudjian, Quang Hieu Duong, Ines Sousa, Thi Thuy Le, Virginie Baylot, Sophie Giusiano, Laurent Daniel, Pauline Brige, Benjamin Guillet, Cyrille Bastide, Carmen Garrido, David Taïeb, Thi Khanh Le, Palma Rocchi   +15 more
wiley   +1 more source

GDNF‐Enriched Small Extracellular Vesicle‐Loaded ROS‐Scavenging Hydrogel Promotes Neural Regeneration After Spinal Cord Injury

Advanced Healthcare Materials, EarlyView.
A glial cell line‐derived neurotrophic factor (GDNF)‐enriched small extracellular vesicle‐loaded reactive oxygen species (ROS)‐scavenging hydrogel integrates sustained neurotrophic delivery with local modulation of oxidative and inflammatory stress after spinal cord injury. The composite hydrogel improves local vesicle retention, protects neural tissue,
Xingyu Zhu, Zhong Liu, Kewei Li, Yuhong Fan, Kangjia Yang, Xiaopeng Sun, Hang Shi, Lixuan Sun, Yang Lou, Min Wang, Peipei Wu, Hui Qian, Qiang Fu, Hua Ding   +13 more
wiley   +1 more source

Microfluidic Engineering of Microgels: A Review of Emerging Technologies, Materials, Fabrication Strategies, and Applications

Advanced Healthcare Materials, EarlyView.
Recent advances in microfluidic technologies for microgel fabrication are critically reviewed, highlighting the capabilities and limitations of major microfluidic platforms and discussing how platform design, material selection, and crosslinking strategies influence microgel architecture and functionality. Current challenges and future opportunities in
Afshin Abrishamkar, Laura Neely, Cynthia Pham, Nada Ibrahim, Alexis Larios‐Cervantes, Ben A. Kertesz, Todd Hoare   +6 more
wiley   +1 more source

Self-assembled liposomes from amphiphilic electrospun nanofibers

, 2011
Amphiphilic nanofibers composed of the hydrophilic polymer polyvinylpyrrolidone K60 (PVP) and soybean lecithin were fabricated using an electrospinning process.
Yu, Deng-Guang, Zhu, L.M., Nicholas P. Chatterton, S. W. Annie Bligh, Bligh, S. W. Annie, Chatterton, N.P., White, Kenneth, Christopher Branford-White, Deng-Guang Yu, Zhu, Li-Min, Branford-White, C.J., Li-Min Zhu, Yu, D.G., White, K.N., Williams, G.R., Kenneth White, Williams, Gareth R., Branford-White, Christopher, Chatterton, Nicholas P., Bligh, S.W.A., Gareth R. Williams   +20 more
core   +1 more source

Anti‐Inflammatory and Neuroactive Effects of Polymer‐Coated Iron Oxide Nanoparticles Functionalized With Interleukin 4 for Spinal Cord Injury

Advanced Healthcare Materials, EarlyView.
Polymer‐coated IONPs functionalized with IL‐4 display respective neuroactive and anti‐inflammatory actions on neural progenitor cells and macrophages/microglia in vitro. When examined chronically in a rat experimental model of spinal cord injury, rGO scaffolds carrying these nanosystems adequately integrate into the lesion, significantly reduce ...
Julia Martínez‐Ramírez, Paloma Lozano‐Picazo, María de Lamo‐Atencia, Andrea Ferreras, Esther Benayas‐Martín, Elena Fernández‐López, Marina Sánchez‐Petidier, Verónica Barranco‐Maresca, Víctor Caz, Anne des Rieux, Juliana M. Rosa, María del Puerto Morales, María C. Serrano   +12 more
wiley   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Drug delivery systems to include liposomes and microparticles in order to aid treatment of glioma. [PDF]

Targeted drug delivery is achieved by enhancing drug availability at the response site while minimising its availability at other sites, especially those that manifest toxicity.
Parkar, Neha
core   +4 more sources

Liposome Clearance

Bioscience Reports, 2002
The clearance rate of liposomal drugs from the circulation is determined by the rate and extent of both drug release and uptake of liposomes by cells of the mononuclear phagocyte system (MPS). Intravenously injected liposomes initially come into contact with serum proteins.
Tatsuhiro, Ishida, Hideyoshi, Harashima, Hiroshi, Kiwada   +2 more
openaire   +2 more sources

Achieving High Spatial Resolution Transmission Electron Microscopy Studies in Closed Liquid Cells

Advanced Materials, EarlyView.
Achieving high spatial resolution is important for resolving nanoscale dynamic processes and structural transformations in liquid environments, yet remains challenging in liquid cell transmission electron microscopy (LCTEM). This review highlights key strategies, including mitigating membrane bulging, displacing or redistributing local liquid ...
Siqi Guo, Hongyu Sun, Le Shu, Xuejin Ge, Raquel Aymerich‐Armengol, Siyuan Zhang, Long Ren, Ningyan Cheng, Christina Scheu, Binghui Ge   +9 more
wiley   +1 more source