Results 241 to 250 of about 44,003 (300)

EPA-Derived diHEPAs Attenuate Lipopolysaccharide-Induced Acute Lung Injury by Regulating Inflammation and Redox Homeostasis. [PDF]

Int J Mol Sci
Su Y, Kwon SK, Choi HS, Han Y, Park JH, Jang YS, Choi JH, Seo JW.   +7 more
europepmc   +1 more source

Antioxidant, Hypotensive, and Antidiabetic Breakthroughs: Bromelain Hydrolysis Unlocks Quinoa's Peptide Potential - <i>In Silico</i> and <i>In Vitro</i> Approach. [PDF]

J Agric Food Chem
Manzanilla-Valdez ML, Montaño S, Martinez-Villaluenga C, Zúñiga F, Boesch C, Hernandez-Alvarez AJ.   +5 more
europepmc   +1 more source

Ferroptosis and Ferroptosis-related autophagy: new therapeutic targets for gastric cancer. [PDF]

Am J Cancer Res
Huang L, Tan T, Mao Y, Kang Y, Wang T, Zheng F.   +5 more
europepmc   +1 more source

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Lipoxygenase inhibitors for the treatment of pancreatic cancer

Expert Review of Anticancer Therapy, 2003
Pancreatic cancer has a dismal prognosis with no effective medical therapy. Therefore, there is a need to search for novel targets for cancer prevention and treatment. The lipoxygenases oxygenate arachidonic acid and other 20-carbon fatty acids and their downstream metabolites have been found to mediate several aspects of pancreatic cancer development ...
Xian-Zhong Ding, T E Adrian
exaly   +3 more sources

Inhibitors of Cyclooxygenase and 5-Lipoxygenase

Current Medicinal Chemistry, 1994
Abstract: Prostaglandin H synthase (PGH synthase) and 5-Lipoxygenase (5-LO) are important enzymes that catalyze the formation of putative intermediates involved in the inflammatory process. The mechanism by which PGH synthase and 5-LO convert their common substrate arachidonic acid (AA) into prostaglandins, thromboxanes and leukotrienes is discussed ...
Donald T Witiak
exaly   +2 more sources

Design, synthesis, molecular modelling and biological evaluation of novel 3-(2-naphthyl)-1-phenyl-1H-pyrazole derivatives as potent antioxidants and 15-Lipoxygenase inhibitors [PDF]

Journal of Enzyme Inhibition and Medicinal Chemistry, 2020
Sahar A Ali, Shahenda Mahgoub, Heba Taha   +2 more
exaly   +2 more sources

Silymarin, an inhibitor of lipoxygenase

Experientia, 1979
Silybin (I), silydianin (II) and silychristin (III), the constituents of silymarin, non-competitively inhibit the lipoxygenase from soybeans (EC 1.13.11.12) in vitro.
F, Fiebrich, H, Koch
openaire   +2 more sources

Anthocyanins as lipoxygenase inhibitors

Molecular Nutrition & Food Research, 2009
AbstractHealth benefits associated with diets rich in anthocyanins are ascribed to multilevel biological activities including antioxidative and anti‐inflammatory effects. The present study addresses lipoxygenase inhibition as a mechanism by which anthocyanins may exert health promoting effects. The inhibitory potential of delphinidin (Dp), cyanidin (Cy)
Bastian, Knaup, Anett, Oehme, Anagnostis, Valotis, Peter, Schreier   +3 more
openaire   +2 more sources