Results 221 to 230 of about 44,003 (300)

<i>Khaya grandifololia</i> exerts multitarget neuroprotective potential against neurodegenerative disorders: <i>In vitro</i> and <i>in silico</i> studies. [PDF]

IBRO Neurosci Rep
Ella FA, Ambamba BDA, Njayou FN, Moundipa PF.   +3 more
europepmc   +1 more source

Emerging Role of Ferroptosis in Diabetes and Associated Complications: When Metabolic Dysregulation Meets Cell Death

Cell Proliferation, Volume 59, Issue 5, May 2026.
This study identifies ferroptosis as a key driver of diabetes and its complications via iron metabolism and lipid peroxidation, elucidates organelle interactions underlying cell vulnerability, and provides insights for targeted therapies against metabolic disorders.
Zheng Wang, Ying Zhang, Yue Xu, Mengyuan Yang, Yuan Wei, Yuan Li, Tongyue Yang, Xu Wang, Chaona Yang, Qi Feng, Guolan Xing   +10 more
wiley   +1 more source

Causal demonstration of adiposity-induced adipose-specific signaling derangements in the pathogenesis of the clinical features of the cardiovascular-kidney metabolic syndrome. [PDF]

Cardiovasc Diabetol
Packer M.
europepmc   +1 more source

B Cell Subsets and Atherosclerosis: Updates and Emerging Concepts

Immunological Reviews, Volume 339, Issue 1, May 2026.
ABSTRACT Atherosclerotic cardiovascular disease (ASCVD) is increasingly recognized not just as a lipid‐driven disease, but as a complex interplay between vascular cells and the immune system. Accumulating evidence highlights a central, yet heterogeneous role for B cells in atherogenesis, with distinct subsets displaying opposing roles.
Sophieke Lems, Megan Grace Mazzei, Amanda C. Foks, Coleen A. McNamara   +3 more
wiley   +1 more source

Advances in Beyond Statin Lipid Therapies for ASCVD Risk Reduction. [PDF]

J Atheroscler Thromb
Shimabukuro M.
europepmc   +1 more source

EIF2α–ATF4–CHAC1 Signalling Links ER Stress to Ferroptosis in Human Aortic Smooth Muscle Cells: Mechanistic Insights and Therapeutic Implications

Journal of Cellular and Molecular Medicine, Volume 30, Issue 9, May 2026.
ABSTRACT Ferroptosis—a regulated, iron‐dependent cell death driven by lipid peroxidation—has been implicated in vascular pathology, yet how endoplasmic reticulum (ER) stress couples to ferroptotic execution in vascular smooth muscle cells (VSMCs) remains unclear.
Changwen Fang, Xiaolong Du, Yadan Wang, Yiqi Jin, Wenbin Wang   +4 more
wiley   +1 more source

The mechanism of heat stress-induced injury in the immature oocytes of zebrafish (Danio rerio). [PDF]

J Reprod Dev
Achadri Y, Kuwahara N, Kimura M, Kanamaru N, Matsukawa K, Edashige K.   +5 more
europepmc   +1 more source

Intracellular NAD+ Depletion Increases Prostanoid Production via p38/COX2 Signalling in FK866‐Induced Senescent Human Umbilical Vein Endothelial Cells

Journal of Cellular and Molecular Medicine, Volume 30, Issue 10, May 2026.
ABSTRACT Vascular endothelial cells maintain vascular homeostasis by releasing mediators with vasoconstrictive and vasorelaxant effects. Prostanoids are bioactive substances synthesised by cyclooxygenase2 (COX2); they preserve vascular function and can increase the risk of cardiovascular disease (CVD) associated with ageing.
Natsuko Kitajima, Takahisa Nakajo, Takeshi Katayoshi, Kentaro Tsuji   +3 more
wiley   +1 more source

Design, synthesis, characterization, biological investigation and docking studies of newly synthesized sulphonyl hydrazide and their derivatives. [PDF]

Sci Rep
Rahman M, Zafar R, Jan MS, Darwish HW, Khattak H, Aschner M, Daglia M, Khan H.   +7 more
europepmc   +1 more source

Stem Cells in Cosmetic Applications: Advancements, Challenges, and Future Directions

Journal of Cosmetic Dermatology, Volume 25, Issue 5, May 2026.
ABSTRACT Background Biotechnology has significantly impacted the cosmetics industry, particularly through the incorporation of plant stem cells, which possess regenerative properties beneficial for skincare. Aims This review aims to evaluate the potential benefits and challenges of using plant stem cells in cosmetics, while discussing future directions
Farid KarkonShayan, Nasim Saderi, Iman Morshedi, Behnaz Ghamari, Sepideh KarkonShayan   +4 more
wiley   +1 more source