Results 91 to 100 of about 4,273 (194)
Journal of Cellular and Molecular Medicine, Volume 29, Issue 22, November 2025.ABSTRACT Long non‐coding RNAs (lncRNAs) play important roles in colorectal cancer (CRC) progression. However, the biological function and regulatory mechanism of small nucleolar RNA host gene 26 (SNHG26) in CRC remain largely unexplored. SNHG26 expression was analysed in CRC tissues and cell lines using quantitative real‐time PCR (qRT‐PCR).
Ziang Wan, Shan Gao
wiley +1 more source
Advanced Science, Volume 12, Issue 37, October 6, 2025.This study provides a volumetric engineered 3D drug reservoir to combat diabetic implant infection. Cu‐doped quantum dots induce cuproptosis‐like bacterial death via metabolic collapse, while glucose oxidase triggers hunger‐triggered mitochondrial protection in host cells.
Dize Li +8 more
wiley +1 more source
Mitochondrial acyl carrier protein (ACP) at the interface of metabolic state sensing and mitochondrial function [PDF]
, 2019 Acyl carrier protein (ACP) is a principal partner in the cytosolic and mitochondrial fatty acid synthesis (FAS) pathways. The active form holo-ACP serves as FAS platform, using its 4′-phosphopantetheine group to present covalently attached FAS ...
Autio, Kaija J. +4 more
core +1 more source
Acute Myocardial Infarction: Molecular Pathogenesis, Diagnosis, and Clinical Management
MedComm, Volume 6, Issue 10, October 2025.Key pathogenic mechanisms in AMI. Oxidative stress and mitochondrial dysfunction induce ROS accumulation, while DAMPs‐PRRs interaction triggers inflammatory cascades. Programmed cell death pathways and epigenetic regulation collectively constitute the core components of AMI pathogenesis.
Mengmeng Zhu +5 more
wiley +1 more source
Impaired Mitochondrial Fatty Acid Synthesis Leads to Neurodegeneration in Mice [PDF]
, 2018 There has been a growing interest toward mitochondrial fatty acid synthesis (mtFAS) since the recent discovery of a neurodegenerative human disorder termed MEPAN (mitochondrial enoyl reductase protein associated neurodegeneration), which is caused by ...
Autio, Kaija J. +9 more
core +1 more source
Immunological and biosynthetic studies of the human pyruvate dehydrogenase complex [PDF]
, 2007 The human pyruvate dehydrogenase multi-enzyme complex (PDC) catalyses the oxidative decarboxylation of pyruvate, transferring the resultant acetyl group to coenzyme A.
Al-Amodi, Hiba Saeed Bagader
core +1 more source
Lipoyltransferase 1 Gene Defect Resulting in Fatal Lactic Acidosis in Two Siblings
Case Reports in Obstetrics and Gynecology, 2016 A term male neonate developed severe intractable lactic acidosis on day of life 1 and died the same day at our institution. The family previously lost another term, female newborn on day of life 1 from suspected sepsis at an outside hospital.
Véronique Taché +6 more
doaj +1 more source
Frontiers in Cell and Developmental BiologyBackgroundColon adenocarcinoma (COAD) remains a major global health challenge with poor prognosis despite advances in treatment, underscoring the need for new biomarkers. As a novel mode of cell death, cuproptosis is thought to be potentially involved in
Zhanhui Ye +10 more
doaj +1 more source
Copper-induced cell death mechanisms and their role in the tumor microenvironment
Frontiers in Cell DeathCopper is an essential cofactor for all organisms. However, it can become toxic if its concentration rises above a specific level. This level is controlled by evolutionary conserved homeostatic mechanisms.
Yujuan Jiao +7 more
doaj +1 more source