Results 111 to 120 of about 4,273 (194)

Inducers of Autophagy and Cell Death: Focus on Copper Metabolism

Ecotoxicology and Environmental Safety
Copper is an essential trace element in biological systems, playing a key role in various physiological functions, including redox reactions and energy metabolism.
Weikang Ling, Shuo Li, Yang Zhu, Xin Wang, Dongmei Jiang, Bo Kang   +5 more
doaj   +1 more source

Brain Lipoyl Dehydrogenase

Journal of Biological Chemistry, 1969
S A Millard, A Kubose, E M Gal
openaire   +1 more source

Targeting SERPINB3–MAPK axis-mediated cuproptosis resistance enhances the response to antitumor immunotherapy

Molecular Cancer
Cuproptosis, a newly identified form of cell death, is closely linked to copper homeostasis and protein lipoylation. Using a multi-omics approach, we firstly reveal that SERPINB3 confers cuproptosis resistance in pancreatic cancer and functions as a ...
Xiao-Xiao Huang, Cheng-Ke Xie, Yi-Chao Mo, Wei Li, Yong-Ding Wu, Zhi-Yuan Li, Hao-Xiang Zhang, Ge Li, Long Jin, Xin-Quan Lin, Jian-Fei Hu, Yin-Hao Chen, Hong-Yi Lin, Shun-Cang Zhu, Jin-Peng Lu, Hou-Juan Zhu, Wan-Wan Wang, Yi Huang, Zu-Wei Wang, Long Huang, Dan-Feng Wang, Yi-Feng Tian, Cheng-Yu Liao, Shi Chen   +23 more
doaj   +1 more source

Analysis of genetic mutations using a recombinant model of the mammalian pyruvate dehydrogenase complex [PDF]

, 2008
The human mitochondrial pyruvate dehydrogenase complex (PDC) is a vital metabolic assembly that controls the key committed step in aerobic carbohydrate utilisation and energy production and as such is responsible for overall glucose homeostasis in man ...
Singh, Geetanjali
core   +1 more source

Lipoyl transferase 1 deficiency [PDF]

, 2020
openaire   +1 more source

Targeting multiple genetic defects of mitochondrial diseases with a single bacterial lipoate protein ligase. [PDF]

Sci Adv
Hu Z, Yu J, Liu Z, Jiang M, Zeng AP.
europepmc   +1 more source

Ferredoxins: master regulators in mitochondrial redox homeostasis and programmed cell death. [PDF]

Redox Biol
Lu Y, Wu Y, Yang C, Zhou Y, Ren X, Li H, Huang H, Pan F, Deng A, Lu Y, Yang J, Tong X, Li Y, Du J.   +13 more
europepmc   +1 more source

A mouse model of MEPAN demonstrates a role for mitochondrial fatty acid synthesis in iron-sulfur cluster and supercomplex formation. [PDF]

Proc Natl Acad Sci U S A
Murdock DG, Janssen KA, Keller K, Mitchell KL, Beauplan M, O'Brien WT, D'Alessandro L, Haltom JA, Wallace DC.   +8 more
europepmc   +1 more source

Role of Ferredoxin 1 <i>(FDX1)</i> in cancer and its therapeutic potential. [PDF]

Cancer Pathog Ther
He F, Zhao H, Gao R, Lu M, Wang S, Chen Y, Peng L, Xia J.   +7 more
europepmc   +1 more source

Copper Dyshomeostasis, Redox Buffering and Immune Aging Converge on Cuproptosis in Age-Related Diseases. [PDF]

Antioxidants (Basel)
Jin Y, Lu K, Yang Y.
europepmc   +1 more source