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Dysregulation of Different Modes of Programmed Cell Death in Rheumatoid Arthritis Fibroblast-Like Synoviocyte. [PDF]
Zhi X +5 more
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Brain lipoyl dehydrogenase. Purification, properties, and inhibitors.
S A, Millard, A, Kubose, E M, Gál
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Copper, Cuproptosis, and Neurodegenerative Diseases. [PDF]
Genchi G +4 more
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Interaction of ferroptosis and cuproptosis in the perspective of pulmonary hypertension. [PDF]
Yang Y, Liang L, Pei W, Sun Y.
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ZFT is the major iron and zinc transporter in <i>Toxoplasma gondii</i>. [PDF]
Aghabi D +8 more
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Mitochondrial phosphopantetheinylation is required for oxidative metabolism. [PDF]
Norden PR +9 more
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Chemical Tagging of Protein Lipoylation
Angewandte Chemie, 2020AbstractProtein lipoylation is a post‐translational modification of emerging importance in both prokaryotes and eukaryotes. However, labeling and large‐scale profiling of protein lipoylation remain challenging. Here, we report the development of iLCL (iodoacetamide‐assisted lipoate‐cyclooctyne ligation), a chemoselective reaction that enables chemical ...
Qi Tang +3 more
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N-lipoyl glucosamine and N-lipoyl glucosaminitol: Substrates for lipoyl dehydrogenase
Archives of Biochemistry and Biophysics, 1969Abstract N - dl -Lipoyl- d -glucosamine and N - dl -lipoyl- d -glucosaminitol were prepared and tested as substrates for lipoyl dehydrogenase (reduced nicotinamide adenine dinucleotide: Lipoamide oxidoreductase, EC 1.6.4.3). It was anticipated that such lipoateamino carbohydrate derivatives would be superior substrates for the enzyme, having ...
A L, Fluharty, G L, Adelson, B P, Gaber
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Quantitative Site-Specific Chemoproteomic Profiling of Protein Lipoylation
Journal of the American Chemical Society, 2022Protein lipoylation is an evolutionarily conserved post-translational modification from prokaryotes to eukaryotes. Lipoylation is implicated with several human diseases, including metabolic disorders, cancer, and Alzheimer's disease. While individual lipoylated proteins have been biochemically studied, a strategy for globally quantifying lipoylation ...
Shuchang Lai +5 more
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Lipoylated Peptides and Proteins
2015Lipoic acid is a heterocyclic sulfur-containing derivative of octanoic acid that is characterized by a 1,2-dithiolane ring. Found in nature as an essential protein cofactor, lipoic acid is implicated in cellular metabolic reactions. In particular, lipoylation is an essential posttranslational modification involved in cellular energetic metabolism ...
Rentier, Cédric +4 more
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