Results 161 to 170 of about 4,273 (194)

Brain lipoyl dehydrogenase. Purification, properties, and inhibitors.

open access: yesThe Journal of biological chemistry, 1969
S A, Millard, A, Kubose, E M, Gál
openaire   +1 more source

Copper, Cuproptosis, and Neurodegenerative Diseases. [PDF]

open access: yesInt J Mol Sci
Genchi G   +4 more
europepmc   +1 more source

ZFT is the major iron and zinc transporter in <i>Toxoplasma gondii</i>. [PDF]

open access: yesElife
Aghabi D   +8 more
europepmc   +1 more source

Mitochondrial phosphopantetheinylation is required for oxidative metabolism. [PDF]

open access: yesMetabolism
Norden PR   +9 more
europepmc   +1 more source

Chemical Tagging of Protein Lipoylation

Angewandte Chemie, 2020
AbstractProtein lipoylation is a post‐translational modification of emerging importance in both prokaryotes and eukaryotes. However, labeling and large‐scale profiling of protein lipoylation remain challenging. Here, we report the development of iLCL (iodoacetamide‐assisted lipoate‐cyclooctyne ligation), a chemoselective reaction that enables chemical ...
Qi Tang   +3 more
openaire   +2 more sources

N-lipoyl glucosamine and N-lipoyl glucosaminitol: Substrates for lipoyl dehydrogenase

Archives of Biochemistry and Biophysics, 1969
Abstract N - dl -Lipoyl- d -glucosamine and N - dl -lipoyl- d -glucosaminitol were prepared and tested as substrates for lipoyl dehydrogenase (reduced nicotinamide adenine dinucleotide: Lipoamide oxidoreductase, EC 1.6.4.3). It was anticipated that such lipoateamino carbohydrate derivatives would be superior substrates for the enzyme, having ...
A L, Fluharty, G L, Adelson, B P, Gaber
openaire   +2 more sources

Quantitative Site-Specific Chemoproteomic Profiling of Protein Lipoylation

Journal of the American Chemical Society, 2022
Protein lipoylation is an evolutionarily conserved post-translational modification from prokaryotes to eukaryotes. Lipoylation is implicated with several human diseases, including metabolic disorders, cancer, and Alzheimer's disease. While individual lipoylated proteins have been biochemically studied, a strategy for globally quantifying lipoylation ...
Shuchang Lai   +5 more
openaire   +2 more sources

Lipoylated Peptides and Proteins

2015
Lipoic acid is a heterocyclic sulfur-containing derivative of octanoic acid that is characterized by a 1,2-dithiolane ring. Found in nature as an essential protein cofactor, lipoic acid is implicated in cellular metabolic reactions. In particular, lipoylation is an essential posttranslational modification involved in cellular energetic metabolism ...
Rentier, Cédric   +4 more
openaire   +1 more source

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