Results 41 to 50 of about 598,516 (216)
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Vortex Assisted Extraction for Propylparaben Analysis in Cosmetics
ASM Science Journal, 2019 Propylparaben is an ester of para-hydroxybenzoic acid and commonly used as a preservative in the cosmetics, pharmaceuticals and food products. However, several recent reports demonstrated that paraben possesses an estrogenic activity and causes cancer ...
Noorashikin Md Saleh
doaj +1 more source
BMC Chemistry, 2019 In this study, a simple one-step ionic liquid-based ultrasound-assisted dispersive liquid–liquid microextraction technique was coupled with high-performance liquid chromatography for the analysis of four pyrethroids in three kinds of traditional Chinese ...
Yiyi Liao +8 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Liquid-liquid extraction of barium with DEPHA: chemical equilibrium
Revista Facultad de Ingeniería Universidad de Antioquia, 2006 The objective of this work was to evaluate a liquid - liquid extraction process to separate barium in aqueous phase by means of an organic phase consisting of DEPHA (bis-2-ethylhexyl phosphate) in kerosene and isopropyl alcohol as modifying agent ...
Gladis Duperly Yaruro +2 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Food Chemistry AdvancesPalm stearin-based mono-diacylglycerols (MDAGs) are food emulsifiers that have not yet been widely developed. Monoacylglycerol (MAG) and diacylglycerol (DAG) are the predominant components of MDAGs.
Gina Libria Nadjamoeddin +4 more
doaj +1 more source