Results 81 to 90 of about 659,295 (264)

An on-line solid phase extraction procedure for the routine quantification of caspofungin by liquid chromatography-tandem mass spectrometry [PDF]

, 2012
Background: Extensive sets of data are required to investigate the potential use of a therapeutic drug monitoring with individualization of dosage of the antimycotic compound caspofungin.
Rieger, Christina, Michael Vogeser, Ostermann, Helmut, Barbara Maier, Christina Rieger, Helmut Ostermann, Fabian Kirchhoff, Spoehrer, Ute, Vogeser, Michael, Ute Spöhrer, Maier, Barbara, Kirchhoff, Fabian   +11 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Corrigendum to “Prediction of methane diffusion coefficient in water using molecular dynamics simulation” [Heliyon 6 (11) (November 2020) e05385]

Heliyon, 2021
Hojatollah Moradi, Hedayat Azizpour, Hossein Bahmanyar, Mohammad Mohammadi, Mahdi Akbari   +4 more
doaj   +1 more source

Solid phase extraction for removal of matrix effects in lipophilic marine toxin analysis by liquid chromatography-tandem mass spectrometry [PDF]

, 2009
The potential of solid phase extraction (SPE) clean-up has been assessed to reduce matrix effects (signal suppression or enhancement) in the liquid chromatography-tandem mass spectrometry (LC¿MS/MS) analysis of lipophilic marine toxins.
Boer, J., de, Bire, Ronel, Bire, R., de Boer, J., de Boer, J.; id_orcid, Jacob de Boer, Boer, J. de, Mulder, Patrick P. J., McElhinney, A. M., Hess, Philipp, McElhinney, M., Philipp Hess, Gerssen, A., Mairead A. McElhinney, Gerssen, Arjen, Ronel Bire, Arjen Gerssen, Bire, L., de Boer, Jacob, Patrick P. J. Mulder, Mulder, P.P.J., Hess, P., McElhinney, Mairead A.   +22 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Liquid-liquid extraction with long wavelength fluorescence detection

, 1994
Long wavelength fluorophores, methylene blue, Rhodamine 800, 3,3'diethyloxacarbocyanine iodide (DODC) and 1, 1',3,3,3' ,3' -hexamethylindotricarbocyanine perchlorate (HIDTCP) were investigated as probes to quantify drugs after liquid-liquid extraction ...
Ravinder K. Hindocha (7166744)
core   +1 more source

Supported liquid membrane-coupled Extraction

Advances in Sample Preparation
Group separation of multiple analytes with diverse physicochemical properties from the same complex sample is significant in clinical diagnosis, environmental monitoring and biomarker identification.
Shengjie Hu, Xiantao Shen, Chuixiu Huang
doaj   +1 more source

Extraction on Paper, an Active Learning Technique to Facilitate Student Understanding of Liquid-Liquid Extraction

, 2019
Undergraduate students often find it difficult to understand the chemical principles underlying liquid-liquid extractions. Explanations on how extractions work at the molecular level in textbook and internet resources are plentiful, but students still do
Renee, Link, William J., Howitz, Simon, Lam, Kate J., McKnelly   +3 more
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source