Results 71 to 80 of about 659,295 (264)

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Ionic Liquid Solvent Design Framework for Extraction of Phytochemicals using Microwave-Assisted Method

open access: yesChemical Engineering Transactions, 2020
Computer aided molecular design (CAMD) has been used widely for solvent design. It is a reverse approach in the selection of solvents for real application.
Nur Rahilah Haji Abd Rahman   +2 more
doaj   +1 more source

A one dimensional model for the prediction of extraction yields in a two phases modified twin-screw extruder [PDF]

open access: yes, 2002
Solid/liquid extraction is performed on raw plant substrate with a modified twin-screw extruder (TSE) used as a thermo-mecanochemical reactor. Visual observations and experimental residence time distributions (RTD) are used to develop a solid transport ...
Prat, Laurent E.   +4 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Microstructure-Enhanced Liquid–Liquid Extraction in a Real-Time Fluorescence Detection Microfluidic Chip

open access: yesMicromachines, 2016
Microfluidic system is widely employed in the detection of environmental contaminants and biological specimens. One of the critical issues which limits the applications of microfluidic chips is the limit of detection of trace specimens.
Penghui Xiong   +4 more
doaj   +1 more source

Liquid-Liquid Extraction Processes

open access: yes, 1983
Liquid-liquid extraction is the separation of one or more components of a liquid solution by contact with a second immiscible liquid called the solvent.
Fair, J. R., Humphrey, J. L.
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Liquid - Liquid Extraction of 2, 3-Butanediol from Fermentation Broth [PDF]

open access: yesIranian Journal of Chemistry & Chemical Engineering, 2012
Recovery of metabolites from fermentation broth by solvent extraction can be used to optimize fermentation processes. End-product reutilization, low product concentration, large volumes of fermentation broth and the requirements for large bioreactors, in
Hassan Pahlavanzadeh   +3 more
doaj  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Liquid-liquid Extraction of Copper(II), Cadmium(II), Lead(II) and Zinc(II) from Perchlorate and Tartrate Media by Di-2-methylnonylphosphoric Acid into Heptane [PDF]

open access: yes, 2009
The liquid-liquid extraction equilibrium of Cu(II), Cd(II), Pb(II) and Zn(II) from 0.10 M perchlorate medium by di-2-methylnonylphosphoric acid (DMNPA) as an extractant dissolved in heptane has been investigated.
XUE, Min   +2 more
core  

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