Results 191 to 200 of about 46,855 (284)

Diagnostic Criteria of Bile Cytology: A Multicenter Comparative Study of Conventional and Liquid-Based Cytology in Japan. [PDF]

open access: yesActa Cytol
Naito Y   +14 more
europepmc   +1 more source

International Collaborative Study on Human Papillomavirus Analytical Thresholds for Sensitivity and Specificity in Cervical Screening

open access: yesJournal of Medical Virology, Volume 98, Issue 5, May 2026.
ABSTRACT Human papillomavirus (HPV) assays vary regarding the minimum amount of virus they detect. We investigated analytical thresholds of HPV detection and cervical screening sensitivity and specificity. One hundred cervical intraepithelial neoplasia grade 2 or worse (CIN2+) cases and 200 matched population‐based controls were obtained at the Swedish
Emel Yilmaz   +22 more
wiley   +1 more source

Role of Liquid-Based Cytology in the Endoscopic Diagnosis of Pancreatic Ductal Adenocarcinoma. [PDF]

open access: yesJ Clin Med
Kitagawa K   +10 more
europepmc   +1 more source

Telomere Dysfunction and Proteostasis Decline Define Distinct Pathways of Cellular Senescence in the Human Respiratory Tract

open access: yesAging Cell, Volume 25, Issue 5, May 2026.
Telomere shortening occurs with age in the respiratory epithelium, but telomere dysfunction‐induced foci (TIF) accumulate only late in life. In contrast, proteostasis decline emerges earlier and correlates with functional impairment, suggesting it may be a primary driver of cellular senescence during physiological aging.
Céline Coquette   +20 more
wiley   +1 more source

Systematic Multiplatform Discovery of Methylation Markers Enables Non‐Invasive Early Detection of Endometrial Cancer

open access: yesCancer Science, Volume 117, Issue 5, Page 1412-1421, May 2026.
We identified key endometrial cancer DNA methylation biomarkers (ZNF626, GRIA4, SPDYA) from cervical cells. The model achieved high endometrial cancer sensitivity and detected 92.86% of Stage I endometrial cancers using TCT samples. ABSTRACT Endometrial cancer, the most common gynecological malignancy with an annual increase of 1%–3%, lacks suitable ...
Yan Cai   +10 more
wiley   +1 more source

Finding More in Less: Precision Medicine for Pancreatic Cancer Using Residual Cytology Samples

open access: yesCytopathology, Volume 37, Issue 3, Page 275-283, May 2026.
The study evaluates the use of residual liquid‐based cytology (LBC) samples from pancreatic ductal adenocarcinoma (PDAC) for molecular analysis. It shows that LBC samples preserve nucleic acid quality and remain suitable for next‐generation sequencing (NGS) and MSI testing even after prolonged storage, underscoring their value when other samples are ...
Raquel Antón‐Peñalver   +17 more
wiley   +1 more source

Evaluation of Diagnostic Accuracy of Directly Sampled Endometrial Cytology Using ThinPrep for Endometrial Malignancies: Comparison With Existing Endometrial Liquid-Based Cytology. [PDF]

open access: yesCytopathology
Ikemoto R   +11 more
europepmc   +1 more source

Validation of Digital Cytology for Primary Diagnosis Across a Range of Specimen Types

open access: yesCytopathology, Volume 37, Issue 3, Page 222-231, May 2026.
This single‐centre validation study demonstrated strong diagnostic concordance between high‐resolution whole‐slide imaging and traditional light microscopy across diverse cytology specimen types. Even with limited prior experience, pathologists found digital cytology feasible and acceptable for diagnostic use.
Talisa Mistry   +8 more
wiley   +1 more source

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