Results 131 to 140 of about 3,019,224 (363)

Application of Sequencing, Liquid Biopsies, and Patient-Derived Xenografts for Personalized Medicine in Melanoma [PDF]

, 2015
María Romina Girotti, Gabriela Gremel, Rebecca Lee, Elena Galvani, Dominic G. Rothwell, Amaya Virós, Amit Kumar Mandal, Kok Haw Jonathan Lim, Grazia Saturno, Simon J. Furney, Franziska Baenke, Malin Pedersen, Jane Rogan, Jacqueline Swan, Matthew Ryan Smith, Alberto Fusi, Deemesh Oudit, Nathalie Dhomen, Ged Brady, Paul Lorigan, Caroline Dive, Richard Marais   +21 more
openalex   +1 more source

Biofabrication of a Filtration Barrier by Integrating Electrospun Membranes and Flow in a Glomerular Co‐Culture

Advanced Healthcare Materials, EarlyView.
An ex vivo glomerular filtration barrier is engineered using electrospun, biomimetic membranes seeded with human glomerular cells. The model supports fenestrated endothelium and podocyte foot processes under flow, mimics size‐selective filtration, and enables disease modeling with hiPSC‐derived podocytes, offering a powerful platform for studying ...
Camilla Mussoni, Anna Rederer, Vladimir Stepanenko, Frank Würthner, Philipp Stahlhut, Jürgen Groll, Mario Schiffer, Taufiq Ahmad, Janina Müller‐Deile   +8 more
wiley   +1 more source

Liquid biopsy - a review

Journal of Education, Health and Sport
Introduction and objective:Hepatocellular carcinoma (HCC) is a leading cause of cancer-related deaths worldwide. Early detection is crucial for better outcomes. Traditional diagnostic methods, such as imaging and biopsies, often fail to detect HCC in early stages.
Weronika Rutkowska-Kawalec, Karolina Michalczuk, Dariusz Fabian, Marek Kurowski, Elżbieta Leszczyńska-Knaga, Natalia Jakubczyk, Paweł Moczydłowski, Monika Ryglewicz, Anna Gliwa, Karolina Kuczapska   +9 more
openaire   +2 more sources

PLUS: Primary Layer for Universal Sensing Enabling Improved Immunocapture of Biomarkers in Clinical Scenarios

Advanced Healthcare Materials, EarlyView.
Primary Layer for Universal Sensing (PLUS), a universal coating for bioprobe immobilization across diverse substrates, is introduced. Unlike conventional methods, PLUS is directly grown from dopamine and avidin, creating a roughened surface with abundant biotin‐binding sites.
Nayoung Son, Chorok Byeon, Haejin Jeong, Hyeonha Jang, Jun Seok Park, Seonki Hong   +5 more
wiley   +1 more source

Clinical metagenomics. [PDF]

, 2019
Clinical metagenomic next-generation sequencing (mNGS), the comprehensive analysis of microbial and host genetic material (DNA and RNA) in samples from patients, is rapidly moving from research to clinical laboratories. This emerging approach is changing
Chiu, Charles Y, Miller, Steven A
core  

Molecular Mechanisms of Extracellular Vesicle Biogenesis and Their Impact on the Design of Custom EVs

Advanced Healthcare Materials, EarlyView.
Extracellular vesicles (EVs) are pivotal mediators of intercellular communication and disease, yet the fundamental mechanisms controlling their biogenesis and cargo selection remain unclear. This limitation hinders their diagnostic utility and therapeutic development.
Luís Carvalho Ferraz, Paulo Pereira, João Vasco Ferreira   +2 more
wiley   +1 more source

Challenges for CTC-based liquid biopsies: low CTC frequency and diagnostic leukapheresis as a potential solution [PDF]

, 2015
Nikolas H. Stoecklein, Johannes Fischer, Dieter Niederacher, Leon W.M.M. Terstappen   +3 more
openalex   +1 more source

Liquid Biopsy Proteomics in Ophthalmology

Journal of Proteome Research
Minimally invasive liquid biopsies from the eye capture locally enriched fluids that contain thousands of proteins from highly specialized ocular cell types, presenting a promising alternative to solid tissue biopsies. The advantages of liquid biopsies include sampling the eye without causing irreversible functional damage, potentially better ...
Julian Wolf, Joel A. Franco, Rui Yip, Mohamed Ziad Dabaja, Gabriel Velez, Fei Liu, Alexander G. Bassuk, Prithvi Mruthyunjaya, Antoine Dufour, Vinit B. Mahajan   +9 more
openaire   +2 more sources

Harnessing Photo‐Energy Conversion in Nanomaterials for Precision Theranostics

Advanced Materials, EarlyView.
Harnessing photo‐energy conversion in nanomaterials enables precision theranostics through light‐driven mechanisms such as photoluminescence, photothermal, photoelectric, photoacoustic, photo‐triggered surface‐enhanced Raman scattering (SERS), and photodynamic processes. This review explores six fundamental principles of photo‐energy conversion, recent
Jingyu Shi, Yadi Fan, Qin Zhang, Yingying Huang, Mo Yang   +4 more
wiley   +1 more source

A liquid biopsy for head and neck cancers [PDF]

, 2015
Henri Schmidt, Arutha Kulasinghe, Chris Perry, Colleen C. Nelson, Chamindie Punyadeera   +4 more
openalex   +1 more source