, 2019 Clinical metagenomic next-generation sequencing (mNGS), the comprehensive analysis of microbial and host genetic material (DNA and RNA) in samples from patients, is rapidly moving from research to clinical laboratories. This emerging approach is changing
Chiu, Charles Y, Miller, Steven A
core
Recent advances of liquid biopsy: Interdisciplinary strategies toward clinical decision‐making [PDF]
, 2023 Han Bao +4 more
openalex +1 more source
Hybrid Scaffolds Decouple Biochemical & Biophysical Regulation of Cell Phenotype
Advanced Healthcare Materials, EarlyView.Replicating tissue‐specific extracellular matrix is crucial for understanding its role in disease. This work demonstrates independent control over stiffness, composition and 3D collagen architecture using hybrid scaffolds: patterned collagen perfused with defined hydrogels.
Xinyuan Song +17 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.This manuscript describes the cultivation of viable microvessels from cryopreserved human brain tissue. When embedded in hydrogels and cultured in microfluidic devices, these microvessels exhibit complex architectures reminiscent of arterioles and capillaries, can be perfused, and display intact barrier function. Collectively, these results demonstrate
Brian J. O'Grady +5 more
wiley +1 more source
Media Coverage of the Benefits and Harms of Testing the Healthy: A protocol for a descriptive study [PDF]
, 2019 Barratt, Alexandra +6 more
core +1 more source
Advanced Healthcare Materials, EarlyView.This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad +3 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.The study presents an antibiotic‐free strategy using medical fabrics coated with supramolecular assemblies of polyarginine and hyaluronic acid. These coatings showed strong antimicrobial and anti‐biofilm activity in vitro and in vivo, achieving major bacterial load reductions, including against MRSA.
Adjara Diarrassouba +18 more
wiley +1 more source
Detection of Metabolites by Proton Ex Vivo NMR, in Vivo MR Spectroscopy Peaks and Tissue Content Analysis: Biochemical-Magnetic Resonance Correlation: Preliminary Results [PDF]
, 2009 *Aim*: Metabolite concentrations by in vivo magnetic resonance spectroscopy and ex vivo NMR spectroscopy were compared with excised normal human tissue relaxation times and tissue homogenate contents. *Hypothesis*: Biochemical analysis
Arun Agrawala +2 more
core +1 more source
An In Situ Embedded B‐MOF Sponge With Shape‐Memory for All‐in‐One Diabetic Wound Therapy
Advanced Healthcare Materials, EarlyView.A smart shape‐memory sponge dressing (P1A3@B‐MOF) is developed for accelerated diabetic wound healing. It achieves pH‐responsive corelease of Zn2+ and salvianolic acid B, synergistically providing antibacterial action, repolarizing macrophages to the M2 phenotype, and promoting angiogenesis.
Hai Zhou +11 more
wiley +1 more source
Steatotic liver disease in chronic hepatitis C related hepatocellular carcinoma: Inflictor or bystander?: Correspondence to editorial on “Dynamic change of metabolic dysfunction-associated steatotic liver disease in chronic hepatitis C patients after viral eradication: A nationwide registry study in Taiwan” [PDF]
Clinical and Molecular HepatologyChung-Feng Huang +5 more
doaj +1 more source