Results 151 to 160 of about 113,588 (316)

The potential of liquid biopsies for the early detection of cancer [PDF]

, 2017
Ellen Heitzer, Samantha Perakis, Jochen B. Geigl, Michael R. Speicher   +3 more
openalex   +1 more source

Liquid biopsy: a step forward in laboratory medicine. [PDF]

Adv Lab Med
Díaz-Lagares A, Jiménez W.
europepmc   +1 more source

Precision Diagnostics in Sports‐Related Traumatic Brain Injury: Pathophysiology, Biomarker Development and Emerging Technologies

Advanced Sensor Research, EarlyView.
Sports‐related traumatic brain injuries (TBIs) remain underdiagnosed, within amateur athletic cohorts. This review critically synthesises recent advancements in AI‐assisted neuroimaging, blood‐based biomarker profiling, wearable biosensing platforms for early detection, injury stratification, and longitudinal surveillance of TBIs.
Daniel Nicol, Mohamed T. Patel, Debarati Bhowmik, Pola Goldberg Oppenheimer   +3 more
wiley   +1 more source

Liquid biopsy in lung cancer. [PDF]

Breathe (Sheff)
Toland S, Ridge P, O'Brien E, Morgan R, Toomey S, Hennessy BT, Ryan DJ.   +6 more
europepmc   +1 more source

Glucose Deprivation‐Induced Disulfidptosis via the SLC7A11‐INF2 Axis: Pan‐Cancer Prognostic Exploration and Therapeutic Validation

Advanced Science, EarlyView.
Glucose deprivation or GLUT1 inhibition induces disulfidptosis in SLC7A11high ovarian cancer cells by promoting cystine accumulation, NADPH/ATP depletion, and F‐actin disulfide formation. SLC7A11 interacts with INF2 to further increase H₂O₂ levels and impair mitochondrial fission, suppressing cell migration. Targeting the SLC7A11–INF2 axis represents a
Zhenyu Song, Qiuming Yao, Lina Huang, Dan Cui, Jun Xie, Leilei Wu, Jianfeng Huang, Bo Zhai, Dan Liu, Xiao Xu   +9 more
wiley   +1 more source

BLOODPAC's collaborations with European Union liquid biopsy initiatives. [PDF]

J Liq Biopsy
Dickey J, Katrivanos E, Leiman LC, Abukhdeir AM, Cardone A, Saritas-Yildirim B, Galamba C, Jankiewicz C, Rolfo C, Bhandari D, Finnegan E, Fenizia F, Celik H, Mehlhorn I, Walker J, Costa JL, Williams K, Sewart M, Olsen M, Wierzba M, Sanzone P, Fijneman RJA, Dumanois R, Mbella V, Gonzales V.   +24 more
europepmc   +1 more source

XBP1s Mediates Cross‐resistance to Combination Treatment of CDK4/6 Inhibitors plus Endocrine Therapy in Breast Cancer

Advanced Science, EarlyView.
Elevated spliced form of X‐box–binding protein 1 (XBP1) correlates with unfavorable responses to endocrine therapy plus CDK4/6 inhibitors in HR+/HER2− advanced breast cancer. XBP1s facilitates cell proliferation and G1/S transition by transcriptionally activating SND1, thereby activating the E2F1 pathway.
Yuting Sang, Shiyang Liu, Xujie Zhou, Weiru Chi, Min Xiong, Ming Chen, Hengyu Ren, Douwaner Liu, Liyi Zhang, Jingyan Xue, Yayun Chi, Jiong Wu   +11 more
wiley   +1 more source

Transforming Cancer Diagnostics: The Emergence of Liquid Biopsy and Epigenetic Markers. [PDF]

MedComm (2020)
Saha D, Kanjilal P, Kaur M, Menon SV, Ashraf A, Kumar MR, Alqahtani T, Atteri S, Uti DE, Dhara B.   +9 more
europepmc   +1 more source

Reprogramming of Fatty Acid Metabolism via PPARα‐Orchestrated FADS2 in Keratinocytes Modulates Skin Inflammation in Psoriasis

Advanced Science, EarlyView.
This study identifies fatty acid desaturase 2 (FADS2) as a key regulator linking polyunsaturated fatty acid (PUFA) metabolism to psoriatic inflammation. FADS2 deficiency impairs docosahexaenoic acid (DHA) biosynthesis, enhances NF‐κB signaling, and promotes neutrophil‐driven skin inflammation. PPARα transcriptionally activates FADS2, and its activation
Jiangluyi Cai, Xue Zhou, Yu Zhuang, Lian Cui, Rui Ma, Youdong Chen, Nan Yang, Qianyu Chen, Yuanyuan Wang, Peiyao Zhu, Lingling Yao, Qian Yu, Xiaomin She, Xuyang Zhou, Yuemeng Huang, Zengyang Yu, Xilin Zhang, Jiajing Lu, Yuling Shi, Chunyuan Guo   +19 more
wiley   +1 more source

Detection and characterization of circulating cell free tumor DNA in cancer patients with malignant solid tumors. Liquid biopsy: a new tool in molecular pathology?

, 2016
Tanja Hinrichsen, Juliane K. Dworniczak, Oliver Wachter, Bernd Dworniczak, Barbara Dockhorn‐Dworniczak   +4 more
openalex   +2 more sources