Results 161 to 170 of about 113,588 (316)

Evidence for circulating cancer stem-like cells and epithelial–mesenchymal transition phenotype in the pleurospheres derived from lung adenocarcinoma using liquid biopsy [PDF]

, 2017
Sheefa Mirza, Nayan Jain, Rakesh Rawal
openalex   +1 more source

Targeting Intratumoral Copper Inhibits Tumor Progression via p62‐Mediated EZH2 Degradation and Potentiates Anti‐PD‐1 Immunotherapy in Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
The authors find that by targeting intratumoral copper, they can enhance p62‐mediated ubiquitination of EZH2 at the Ub‐K63 site by suppressing copper binding to SMURF2, an E3 ligase of EZH2, leading to its autophagic degradation. This mechanism suppressed OSCC progression and potentiated anti‐PD‐1 immunotherapy, highlighting a potential new therapeutic
Xiaohu Lin, Wanling Chen, Bo Li, Zhang Zhao, Zhonglin Yu, Xu‐Yun Zhao, Xuan Zhou, Zhien Feng, Chengzhong Lin, Wei Cao   +9 more
wiley   +1 more source

Treatment-induced changes in the androgen receptor axis: Liquid biopsies as diagnostic/prognostic tools for prostate cancer [PDF]

, 2017
Stefan Preković, Thomas Van den Broeck, Lisa Moris, Elien Smeets, Frank Claessens, Steven Joniau, Christine Helsen, Gerhardt Attard   +7 more
openalex   +1 more source

Why the Therapeutic Impact of RAS Mutation Clearance in Plasma ctDNA Deserves to Be Further Explored in Metastatic Colorectal Cancer

Frontiers in Oncology, 2019
Chiara Nicolazzo, Francesca Belardinilli, Salvatore Caponnetto, Angela Gradilone, Enrico Cortesi, Giuseppe Giannini, Giuseppe Giannini, Paola Gazzaniga   +7 more
doaj   +1 more source

Liquid biopsy biomarkers in cervical cancer: A systematic review and meta-analysis. [PDF]

J Liq Biopsy
Njangiru IK, Tayeb BA, Ali H, Kamil RM.
europepmc   +1 more source

A Compartmentalized Joint‐on‐chip (JoC) Model to Unravel the Contribution of Cartilage and Synovium to Osteoarthritis Pathogenesis

Advanced Science, EarlyView.
A compartmentalized joint‐on‐chip (JoC) platform is here developed, modelling the interactions between cartilage and synovium in osteoarthritis (OA). Using independent culture and mechanical/biochemical stimulation, the JoC revealed how inflammation and mechanical damage drive mutual tissue changes.
Cecilia Palma, Shima Salehi, Michela Anna Polidoro, Matteo Moretti, Marco Rasponi, Silvia Lopa, Paola Occhetta   +6 more
wiley   +1 more source

Liquid Biopsy in Lung Cancer: A Perspective From Members of the Pulmonary Pathology Society

, 2016
Lynette M. Sholl, Dara L. Aisner, Timothy Craig Allen, Mary Beth Beasley, Philip T. Cagle, Vera Luíza Capelozzi, Sanja Đačić, Lida P. Hariri, Keith M. Kerr, Sylvie Lantuéjoul, Mari Mino‐Kenudson, Kirtee Raparia, Natasha Rekhtman, Sinchita Roy‐Chowdhuri, Eric Thunnissen, Ming‐Sound Tsao, Marina Vivero, Yasushi Yatabe   +17 more
openalex   +1 more source

Advanced Microfluidics for Single Cell‐Based Cancer Research

Advanced Science, EarlyView.
Cutting‐edge microfluidic platforms are transforming single‐cell cancer research. This review highlights advanced technologies, from droplet microfluidics to tumour‐chips, that enable functional and spatial single‐cell analyses. By integrating biosensing, immune components, and patient‐derived materials, these systems offer new insights into tumour ...
Adriana Carneiro, Marta Aranda Palomer, Margarida Esteves, Carolina Rodrigues, José Maria Fernandes, Francisca Oliveira, Alexandra Teixeira, Carlos Honrado, Lorena Dieguez, Sara Abalde‐Cela, Miguel Xavier   +10 more
wiley   +1 more source

First prospective multicenter real-world RAS mutation comparison between OncoBEAM-based liquid biopsy and tissue analysis [PDF]

, 2017
Jesús García‐Foncillas, Josep Tabernero, Enrique Aranda, Manuel Benavides, C.J. Camps, Rafael López‐López, Clara Montagut, A. Antón Torres, Guillermo López-Vivanco, Eduardo Díaz‐Rubio, Federico Rojo, Ana Vivancos   +11 more
openalex   +1 more source

Prediction of exosomal miRNA-based biomarkers for liquid biopsy. [PDF]

Sci Rep
Arora A, Raghava GPS.
europepmc   +1 more source