Results 181 to 190 of about 126,740 (294)

Targeting Tex10 Overcomes Oxaliplatin Resistance by Competitively Disrupting the Non‐Canonical BAF Complex in Colorectal Cancer

Advanced Science, EarlyView.
This study reveals that Tex10 drives oxaliplatin resistance in colorectal cancer by competitively binding BRD9 to disrupt the ncBAF complex, thereby suppressing AMBRA1 transcription and ULK1‐mediated autophagy. Gemcitabine is identified as a direct Tex10 inhibitor that restores autophagy and overcomes resistance.
Ping Xu, Jie Huang, Xiaojin Gao, Lin Deng, Yanheng Deng, Denglu Wang, Chunlei Yu, Yunxiang Zhang, Jingdong Li, Xiaocong Xiang   +9 more
wiley   +1 more source

The role of liquid biopsy as a catalyst for sustained progress in precision oncology – Perspective of the young committee of the international society of liquid biopsy

The Journal of Liquid Biopsy
Erick F. Saldanha, Eleonora Nicolo, Konstantinos Venetis, Diego de Miguel-Perez, Ana Ortega-Franco, Angelo Dipasquale, Mohamed A. Gouda, Surbhi Singhal, George Adigbli, Carolina Reduzzi   +9 more
doaj   +1 more source

Lexicon for Clonal Hematopoiesis in Liquid Biopsy. [PDF]

Clin Transl Sci
Tell R, Zehir A, Anfora AT, Basu G, Beidelschies M, Compton C, Cristiano S, Godsey JH, Hu J, Johann DJ, Juntilla M, Kansal R, Lo C, Lopez Ramos D, Mahaganapathy V, Merriam D, Rolfo C, Russell H, Singh U, Stetson D, You M, Leiman LC.   +21 more
europepmc   +1 more source

A Solution for Exosome‐Based Analysis: Surface‐Enhanced Raman Spectroscopy and Artificial Intelligence

Advanced Intelligent Discovery, EarlyView.
Exosomes are emerging as powerful biomarkers for disease diagnosis and monitoring. This review highlights the integration of surface‐enhanced Raman spectroscopy with artificial intelligence to enhance molecular fingerprinting of exosomes. Machine learning and deep learning techniques improve spectral interpretation, enabling accurate classification of ...
Munevver Akdeniz, Zakarya Al‐Shaebi, Omer Aydin   +2 more
wiley   +1 more source

Decoding Brain Metastasis With Liquid Biopsy: Biomarkers and Technologies in EGFR-Mutant NSCLC. [PDF]

Cancer Med
Sun Y, Wang Q, Zhu P, Li Z, Liu T, Yin R.   +5 more
europepmc   +1 more source

A Computational Approach for Biomimetic Design of Liver‐On‐A‐Chip

Advanced Intelligent Discovery, EarlyView.
A biomimetic liver‐on‐a‐chip with antiparallel perfusion was designed using COMSOL‐guided simulation to replicate hepatic acinus transport. Full‐scale modelling revealed diffusion‐dominated, length‐dependent nutrient gradients and low‐shear conditions.
Zhenxu Yang, Qiankun Yin, Qingxin Liu, Zhejun Xu, Ye Zhang, Christopher Vega‐Sánchez, Xiaochen Liu, Daniele Vigolo, Jiao Jiao Li, Ken‐Tye Yong   +9 more
wiley   +1 more source

Access to diagnosis using liquid biopsy (ADLiB): Identifying lymphoma in a tuberculosis-endemic setting. [PDF]

Hemasphere
Antel K, Xiong N, Merrill M, Chen T, McGrath L, Droessler C, van der Schyff M, Wu MX, Cheddie D, Slome C, McBride L, Day J, Mohamed Z, Fakie N, Mbatani N, Shultz C, Meintjes G, Tyekucheva S, Cohen EF, Tolstorukov MY, Verburgh E, Murakami MA.   +21 more
europepmc   +1 more source

Autonomous AI‐Driven Design for Skin Product Formulations

Advanced Intelligent Discovery, EarlyView.
This review presents a comprehensive closed‐loop framework for autonomous skin product formulation design. By integrating artificial intelligence‐driven experiment selection with automated multi‐tiered assays, the approach shifts development from trial‐and‐error to intelligent optimisation.
Yu Zhang, Yongrui Xiao, Chunlin Chen, Dimitrios Tsaoulidis, Kai Yang, Tao Chen   +5 more
wiley   +1 more source

[Liquid biopsy].

Medicina, 2016
openaire   +3 more sources

Method Evaluation of Liquid Biopsy Proteomics for Limited Plasma Volume. [PDF]

Mol Cell Proteomics
Takahashi R, Prodinger F, Matsui A.
europepmc   +1 more source