Results 181 to 190 of about 3,006,723 (410)
Reihs et al. present the development of a humanized, animal‐free synovial membrane model for osteoarthritis. Methods include 3D biochip cultures of human‐primary OA synoviocytes with matrix and serum surrogates. Results show replication of synovial architecture and increased Yap1 expression.
Eva I. Reihs+17 more
wiley +1 more source
AIMSPec‐LoC is a novel lab‐on‐a‐chip platform integrating size‐based extracellular vesicle (EVs) separation with label‐free Raman spectroscopy and AI‐powered classification via SKiNET. This high‐throughput, portable system enables real‐time, multiplexed molecular fingerprinting of EVs from biofluids, offering transformative potential for early, non ...
Emma Buchan+3 more
wiley +1 more source
The origin, hormonal nature, and action of hepatotrophic substances in portal venous blood [PDF]
The hepatotrophic factors previously reported to be in splanchnic venous blood are pancreatic hormones and specifically insulin and glucagon. Of these, insulin is anabolic and glucagon is mainly catabolic but not exclusively so, since glucagon also has ...
Brown, TH+6 more
core
Targeted proteomics identifies liquid-biopsy signatures for extracapsular prostate cancer [PDF]
Yunee Kim+12 more
openalex +1 more source
Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee+9 more
wiley +1 more source
MXene-based nanomaterials for antibacterial and wound healing
MXenes, as a new type of two-dimensional nanomaterial, have great potential for biomedical applications due to their unique structural features and excellent physicochemical properties.
Hui Li+5 more
doaj +1 more source
Applications of DNA-Based Liquid Biopsy for Central Nervous System Neoplasms [PDF]
Joanna Wang, Chetan Bettegowda
openalex +1 more source
Microphysiological Systems for Comorbidity Studies: Chronic Kidney Disease and Osteoarthritis
This review highlights the potential of organ‐on‐a‐chip systems for studying comorbidities, using chronic kidney disease (CKD) and osteoarthritis (OA) as examples. It summarizes recent advances in kidney‐on‐a‐chip and joint‐on‐a‐chip models and discusses their current and potential application in investigating CKD, OA, and CKD‐OA comorbidity, aiming to
Mingying Han+7 more
wiley +1 more source
Mapping breast cancer therapy with circulating tumor cells: The expert perspective
Circulating tumor cells (CTCs) have emerged as a key prognostic biomarker for breast cancer, with their role becoming more pronounced in metastatic cases.
Lorenzo Gerratana+6 more
doaj